8BBH
The crystal structure of a mouse Fab fragment TL1 in complex with a human Glucose-6-phosphate isomerase peptide 293-307
Summary for 8BBH
Entry DOI | 10.2210/pdb8bbh/pdb |
Descriptor | Glucose-6-phosphate isomerase, Heavy Chain of TL1 Fab fragment, Light Chain of TL1 Fab fragment, ... (4 entities in total) |
Functional Keywords | antibody fab fragment, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 3 |
Total formula weight | 48744.60 |
Authors | Ge, C.,Holmdahl, R.,Li, T. (deposition date: 2022-10-13, release date: 2022-12-21, Last modification date: 2023-07-05) |
Primary citation | Li, T.,Ge, C.,Kramer, A.,Sareila, O.,Leu Agelii, M.,Johansson, L.,Forslind, K.,Lonnblom, E.,Yang, M.,Xu, B.,Li, Q.,Cheng, L.,Bergstrom, G.,Fernandez, G.,Kastbom, A.,Rantapaa-Dahlqvist, S.,Gjertsson, I.,Holmdahl, R. Pathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage. Ann Rheum Dis, 82:799-808, 2023 Cited by PubMed: 36858822DOI: 10.1136/ard-2022-223633 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.619 Å) |
Structure validation
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