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2DQT
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High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog
分子名称: IMMUNOGLOBULIN 6D9, [1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL ESTER
著者Kristensen, O, Vassylyev, D.G, Tanaka, F, Ito, N, Morikawa, K, Fujii, I.
登録日2006-05-30
公開日2006-06-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis
J.Mol.Biol., 369, 2007
2DRU
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Crystal structure and binding properties of the CD2 and CD244 (2B4) binding protein, CD48
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, chimera of CD48 antigen and T-cell surface antigen CD2
著者Evans, E.J, Ikemizu, S, Davis, S.J.
登録日2006-06-15
公開日2006-07-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure and Binding Properties of the CD2 and CD244 (2B4)-binding Protein, CD48
J.Biol.Chem., 281, 2006
2DTM
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Thermodynamic and structural analyses of hydrolytic mechanism by catalytic antibodies
分子名称: IMMUNOGLOBULIN 6D9
著者Oda, M, Ito, N, Tsumuraya, T, Suzuki, K, Fujii, I.
登録日2006-07-13
公開日2007-05-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis
J.Mol.Biol., 369, 2007
2AGJ
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Crystal Structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Yvo Fab, Heavy Chain, ...
著者Ramsland, P.A, Terzyan, S.S, Cloud, G, Bourne, C.R, Farrugia, W, Tribbick, G, Geysen, H.M, Moomaw, C.R, Slaughter, C.A, Edmundson, A.B.
登録日2005-07-27
公開日2006-05-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody
Biochem.J., 395, 2006
2AJU
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Cyrstal structure of cocaine catalytic antibody 7A1 Fab'
分子名称: ANTIBODY 7A1 FAB'
著者Zhu, X, Wilson, I.A.
登録日2005-08-02
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2AQ1
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BU of 2aq1 by Molmil
Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant
分子名称: Enterotoxin type C-3, T-cell receptor beta chain V
著者Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
登録日2005-08-17
公開日2006-03-21
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2AJV
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Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with Cocaine
分子名称: Antibody 7A1 Fab', COCAINE
著者Zhu, X, Wilson, I.A.
登録日2005-08-02
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2AJS
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Crystal structure of cocaine catalytic antibody 7A1 Fab' in complex with heptaethylene glycol
分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Antibody 7A1 FAB', GLYCEROL, ...
著者Zhu, X, Wilson, I.A.
登録日2005-08-02
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2AJZ
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Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with ecgonine methyl ester
分子名称: 3-HYDROXY-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER, Antibody 7A1 Fab'
著者Zhu, X, Wilson, I.A.
登録日2005-08-02
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2A1W
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Anti-cocaine antibody 7.5.21, crystal form I
分子名称: SULFATE ION, immunoglobulin heavy chain, immunoglobulin light chain kappa
著者Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A.
登録日2005-06-21
公開日2005-06-28
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Flexibility Of Packing: Four Crystal Forms Of An Anti-Cocaine Antibody 7.5.21
To be Published
2A6K
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Crystal Structure Analysis of the germline antibody 36-65 Fab in complex with the dodecapeptide SLGDNLTNHNLR
分子名称: DODECAPEPTIDE: SLGDNLTNHNLR, Germline antibody 36-65 Fab heavy chain, Germline antibody 36-65 Fab light chain
著者Sethi, D.K, Agarwal, A, Manivel, V, Rao, K.V, Salunke, D.M.
登録日2005-07-03
公開日2006-06-13
最終更新日2018-03-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response.
Immunity, 24, 2006
2AI0
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Anti-Cocaine Antibody 7.5.21, Crystal Form III
分子名称: GLYCEROL, Immunoglobulin Heavy Chain, Immunoglobulin Light Chain kappa, ...
著者Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A.
登録日2005-07-28
公開日2005-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Flexibility of Packing: Four Crystal Forms of an Anti-Cocaine Antibody 7.5.21
To be Published
2CKB
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BU of 2ckb by Molmil
STRUCTURE OF THE 2C/KB/DEV8 COMPLEX
分子名称: ALPHA, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ...
著者Garcia, K.C, Degano, M, Wilson, I.A.
登録日1998-01-14
公開日1998-04-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen.
Science, 279, 1998
2E7L
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BU of 2e7l by Molmil
Structure of a high-affinity mutant of the 2C TCR in complex with Ld/QL9
分子名称: Beta-chain, Cytotoxic Tcell receptor, H-2 class I histocompatibility antigen, ...
著者Garcia, K.C, Colf, L.A.
登録日2007-01-11
公開日2007-04-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献How a single T cell receptor recognizes both self and foreign MHC.
Cell(Cambridge,Mass.), 129, 2007
4MNH
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BU of 4mnh by Molmil
Structure of the DP10.7 TCR
分子名称: Human nkt tcr alpha chain, T-cell receptor gamma chain V region PT-gamma-1/2, Human nkt tcr beta chain
著者Luoma, A.M, Adams, E.J.
登録日2013-09-10
公開日2013-12-18
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells.
Immunity, 39, 2013
4MYW
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Structure of HSV-2 gD bound to nectin-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ...
著者Lu, G, Zhang, N, Qi, J, Li, Y, Chen, Z, Zheng, C, Yan, J, Gao, G.F.
登録日2013-09-28
公開日2014-10-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.189 Å)
主引用文献Crystal structure of herpes simplex virus 2 gD bound to nectin-1 reveals a conserved mode of receptor recognition.
J.Virol., 88, 2014
4NHU
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The M33 TCR p3M33l/H-2 Ld Complex
分子名称: 2C m33 alpha VmCh chimera, 2C m33 beta VmCh chimera, H-2 class I histocompatibility antigen, ...
著者Birnbaum, M.E, Adams, J.J, Garcia, K.C.
登録日2013-11-05
公開日2015-05-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Interrogating TCR Signal Strength and Cross-Reactivity by Yeast Display of pMHC
To be Published
4NJA
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BU of 4nja by Molmil
Crystal structure of Fab 6C8 in complex with MPTS
分子名称: 6C8 heavy chain, 6C8 light chain, 8-methoxypyrene-1,3,6-trisulfonic acid, ...
著者Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
登録日2013-11-08
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
4NQC
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Crystal structure of TCR-MR1 ternary complex and covalently bound 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2013-11-25
公開日2014-04-16
最終更新日2014-11-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T-cell activation by transitory neo-antigens derived from distinct microbial pathways.
Nature, 509, 2014
4NUG
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BU of 4nug by Molmil
Crystal structure of HIV-1 broadly neutralizing antibody PGT151
分子名称: HEXAETHYLENE GLYCOL, PGT151 heavy chain, PGT151 light chain
著者Blattner, C, Wilson, I.A.
登録日2013-12-03
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8617 Å)
主引用文献Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.
Immunity, 40, 2014
4NM8
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Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8043, ...
著者Lee, P.S, Wilson, I.A.
登録日2013-11-14
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.0041 Å)
主引用文献A common solution to group 2 influenza virus neutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
5UGY
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Influenza hemagglutinin in complex with a neutralizing antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH65 heavy chain, ...
著者Whittle, J.R.R, Jenni, S, Harrison, S.C.
登録日2017-01-10
公開日2017-01-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin.
Proc. Natl. Acad. Sci. U.S.A., 108, 2011
4NQD
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Crystal structure of TCR-MR1 ternary complex and non-covalently bound 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2013-11-25
公開日2014-04-16
最終更新日2014-11-19
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献T-cell activation by transitory neo-antigens derived from distinct microbial pathways.
Nature, 509, 2014
4O5L
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Crystal structure of broadly neutralizing antibody F045-092
分子名称: Fab F045-092 heavy chain, Fab F045-092 light chain, PHOSPHATE ION
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5045 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4O5I
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Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab F045-092 heavy chain, ...
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (6.501 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014

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件を2024-08-07に公開中

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