PDB: 1154 件ウェブページステータス検索Chemie searchBIRD

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5TDE	TEV Cleaved Human ATP Citrate Lyase Bound to Citrate 分子名称: ATP-citrate synthase, CITRATE ANION, DIHYDROGENPHOSPHATE ION, ... 著者 Hu, J, Fraser, M.E. 登録日 2016-09-19 公開日 2017-08-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
8RJL	Structure of a first order Sierpinski triangle formed by the H369R mutant of the citrate synthase from Synechococcus elongatus 分子名称: Citrate synthase 著者 Lo, Y.K, Bohn, S, Sendker, F.L, Schuller, J.M, Hochberg, G. 登録日 2023-12-21 公開日 2024-02-28 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 Emergence of fractal geometries in the evolution of a metabolic enzyme. Nature, 628, 2024
8RJK	Pseudoatomic model of a second-order Sierpinski triangle formed by the citrate synthase from Synechococcus elongatus 分子名称: Citrate synthase 著者 Lo, Y.K, Bohn, S, Sendker, F.L, Schuller, J.M, Hochberg, G. 登録日 2023-12-21 公開日 2024-02-28 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (5.91 Å) 主引用文献 Emergence of fractal geometries in the evolution of a metabolic enzyme. Nature, 628, 2024
8GMF	R153M variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis 分子名称: citrate synthase 著者 Pathirage, R, Ronning, D. 登録日 2023-03-25 公開日 2023-06-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
8BP7	Citrate-bound hexamer of Synechococcus elongatus citrate synthase 分子名称: CITRIC ACID, Citrate synthase, MAGNESIUM ION, ... 著者 Mais, C.-N, Sendker, F, Bange, G. 登録日 2022-11-16 公開日 2024-04-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Emergence of fractal geometries in the evolution of a metabolic enzyme. Nature, 628, 2024
1AMZ	CHICKEN CITRATE SYNTHASE COMPLEX WITH NITROMETHYLDE-COA AND MALATE 分子名称: CITRATE SYNTHASE, D-MALATE, NITROMETHYLDETHIA COENZYME A 著者 Usher, K.C, Remington, S.J. 登録日 1997-06-19 公開日 1997-12-24 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mechanisms of Enzyme-Catalyzed Deprotonation of Acetyl-Coenzyme A To be Published
1AL6	CHICKEN CITRATE SYNTHASE COMPLEX WITH N-HYDROXYAMIDO-COA AND OXALOACETATE 分子名称: CITRATE SYNTHASE, N-HYDROXYAMIDOCARBOXYMETHYLDETHIA COENZYME *A, OXALOACETATE ION 著者 Usher, K.C, Remington, S.J. 登録日 1997-06-12 公開日 1997-12-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mechanisms of Enzyme-Catalyzed Deprotonation of Acetyl-Coenzyme A To be Published
8S97	C143W variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis 分子名称: 1,2-ETHANEDIOL, citrate synthase 著者 Pathirage, R, Ronning, D. 登録日 2023-03-27 公開日 2023-06-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
8GM9	Structure of Citrate Synthase(CitA) in Mycobacterium Tuberculosis 分子名称: 1,2-ETHANEDIOL, ACRYLIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Pathirage, R, Ronning, D, Favrot, L. 登録日 2023-03-24 公開日 2023-06-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
8GLL	R149E variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... 著者 Pathirage, R, Ronning, D, Petit, C. 登録日 2023-03-22 公開日 2023-06-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
8GLB	Selenomethionine Derivatized Citrate Synthase (CitA) in Mycobacterium tuberculosis with Pyruvate 分子名称: 1,2-ETHANEDIOL, PYRUVIC ACID, citrate synthase 著者 Pathirage, R, Ronning, D, Favrot, L. 登録日 2023-03-21 公開日 2023-06-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
8GMK	Pyruvate bound structure of Citrate Synthase (CitA) in Mycobacterium Tuberculosis 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PYRUVIC ACID, ... 著者 Pathirage, R, Ronning, D, Yamsek, M. 登録日 2023-03-26 公開日 2023-06-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
8GQZ	Crystal structure of mitochondrial citrate synthase (Cit1) from Saccharomyces cerevisiae 分子名称: ACETATE ION, CHLORIDE ION, Citrate synthase, ... 著者 Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. 登録日 2022-08-31 公開日 2023-04-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci Adv, 9, 2023
8GR8	Crystal structure of peroxisomal citrate synthase (Cit2) from Saccharomycescerevisiae 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Citrate synthase, ... 著者 Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. 登録日 2022-09-01 公開日 2023-04-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci Adv, 9, 2023
8GR9	Crystal structure of peroxisomal citrate synthase (Cit2) from Saccharomyces cerevisiae in complex with oxaloacetate and coenzyme-A 分子名称: CHLORIDE ION, COENZYME A, Citrate synthase, ... 著者 Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. 登録日 2022-09-01 公開日 2023-04-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci Adv, 9, 2023
5LQM	Structure of quinolinate synthase Y21F mutant in complex with citrate 分子名称: CITRATE ANION, IRON/SULFUR CLUSTER, Quinolinate synthase A 著者 Volbeda, A, Fontecilla-Camps, J.C. 登録日 2016-08-17 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Crystal Structures of Quinolinate Synthase in Complex with a Substrate Analogue, the Condensation Intermediate, and Substrate-Derived Product. J.Am.Chem.Soc., 138, 2016
6XOW	CryoEM structure of human presequence protease in partial close state 2, induced by presequence of citrate synthase 分子名称: Presequence protease, mitochondrial 著者 Liang, W.G, Tang, W. 登録日 2020-07-07 公開日 2021-07-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 CryoEM structure of human presequence protease in partial open state 2, induced by presequence of citrate synthase To Be Published
2IBP	Crystal Structure of Citrate Synthase from Pyrobaculum aerophilum 分子名称: ACETATE ION, Citrate synthase, MAGNESIUM ION 著者 Boutz, D.R, Yeates, T.O, Cascio, D. 登録日 2006-09-11 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Discovery of a thermophilic protein complex stabilized by topologically interlinked chains. J.Mol.Biol., 368, 2007
5TDZ	TEV Cleaved Human ATP Citrate Lyase Bound to Tartrate and ADP 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Hu, J, Fraser, M.E. 登録日 2016-09-20 公開日 2017-08-09 最終更新日 2017-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
5TDF	TEV Cleaved Human ATP Citrate Lyase Bound to 4S hydroxycitrate 分子名称: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ADENINE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Hu, J, Fraser, M.E. 登録日 2016-09-19 公開日 2017-08-09 最終更新日 2017-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
6POE	Structure of ACLY in complex with CoA 分子名称: ATP-citrate synthase, COENZYME A 著者 Wei, X, Marmorstein, R. 登録日 2019-07-03 公開日 2019-12-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
6HXP	Structure of citryl-CoA lyase from Hydrogenobacter thermophilus 分子名称: COENZYME A, Citryl-CoA lyase, SULFATE ION 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
3O8J	Crystal structure of 2-methylcitrate synthase (PrpC) from Salmonella typhimurium 分子名称: 2-methylcitrate synthase, GLYCEROL 著者 Chittori, S, Savithri, H.S, Murthy, M.R.N. 登録日 2010-08-03 公開日 2011-04-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Crystal structure of Salmonella typhimurium 2-methylcitrate synthase: Insights on domain movement and substrate specificity J.Struct.Biol., 174, 2011
4TVO	Structure of Malate Dehydrogenase from Mycobacterium tuberculosis 分子名称: Malate dehydrogenase, SODIUM ION, SULFATE ION 著者 Ferraris, D.M, Rizzi, M. 登録日 2014-06-27 公開日 2015-01-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of citrate synthase and malate dehydrogenase of Mycobacterium tuberculosis. Proteins, 83, 2015
6O0H	Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, methyl 3-chloro-5-[(4,6-difluoro[1,1'-biphenyl]-3-yl)sulfamoyl]-4-hydroxybenzoate 著者 Wei, J, Tong, L. 登録日 2019-02-16 公開日 2019-04-17 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 An allosteric mechanism for potent inhibition of human ATP-citrate lyase. Nature, 568, 2019

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