7RLD
| Cryo-EM structure of human p97-E470D mutant bound to ADP. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | 登録日 | 2021-07-23 | 公開日 | 2021-09-22 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
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7RLB
| Cryo-EM structure of human p97-A232E mutant bound to ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | 登録日 | 2021-07-23 | 公開日 | 2021-09-22 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
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7K59
| Structure of apo VCP hexamer generated from bacterially recombinant VCP/p97 | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | 登録日 | 2020-09-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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7K57
| Structure of apo VCP dodecamer generated from bacterially recombinant VCP/p97 | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | 登録日 | 2020-09-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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7K56
| Structure of VCP dodecamer purified from H1299 cells | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | 登録日 | 2020-09-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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7VCT
| Human p97 single hexamer conformer III with D1-ATPgammaS and D2-ADP bound | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | 登録日 | 2021-09-04 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-09 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
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7VCS
| Human p97 double hexamer conformer II with ATPgammaS bound | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | 登録日 | 2021-09-03 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-09 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
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7VCX
| Human p97 single hexamer conformer II with ATPgammaS bound | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | 登録日 | 2021-09-04 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-09 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
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7VCU
| Human p97 double hexamer conformer I with D1-ATPgammaS and D2-ADP bound | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | 登録日 | 2021-09-04 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-09 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
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7VCV
| Human p97 single hexamer conformer I with ATPgammaS bound | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | 登録日 | 2021-09-04 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-09 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
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7WUB
| Cryo-EM structure of dodecamer P97 | 分子名称: | 3-[3-cyclopentylsulfanyl-5-[[3-methyl-4-(4-methylsulfonylphenyl)phenoxy]methyl]-1,2,4-triazol-4-yl]pyridine, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Liu, S, Wang, T. | 登録日 | 2022-02-08 | 公開日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Cryo-EM structure of dodecamer P97 at 2.99 Angstroms resolution To Be Published
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7MHS
| Structure of p97 (subunits A to E) with substrate engaged | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Xu, Y, Han, H, Cooney, I, Hill, C.P, Shen, P.S. | 登録日 | 2021-04-15 | 公開日 | 2022-05-11 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Active conformation of the p97-p47 unfoldase complex. Nat Commun, 13, 2022
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7OAT
| Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Petrovic, S, Heinemann, U, Roske, Y. | 登録日 | 2021-04-20 | 公開日 | 2022-08-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.995 Å) | 主引用文献 | Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D. Proc.Natl.Acad.Sci.USA, 120, 2023
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8DAR
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8DAU
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8DAW
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8DAS
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8DAT
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8DAV
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7PUX
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8B5R
| p97-p37-SPI substrate complex | 分子名称: | I3 sequence being threaded through the p97 channel, Protein phosphatase 1 regulatory subunit 7, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, ... | 著者 | van den Boom, J, Marini, G, Meyer, H, Saibil, H. | 登録日 | 2022-09-24 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structural basis of ubiquitin-independent PP1 complex disassembly by p97. Embo J., 42, 2023
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8FCL
| Cryo-EM structure of p97:UBXD1 closed state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | 著者 | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | 登録日 | 2022-12-01 | 公開日 | 2023-06-21 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | 主引用文献 | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
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8FCQ
| Cryo-EM structure of p97:UBXD1 PUB-in state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | 著者 | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | 登録日 | 2022-12-01 | 公開日 | 2023-06-21 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
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8FCP
| Cryo-EM structure of p97:UBXD1 para state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | 著者 | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | 登録日 | 2022-12-01 | 公開日 | 2023-06-21 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
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8FCT
| Cryo-EM structure of p97:UBXD1 lariat mutant | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | 著者 | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | 登録日 | 2022-12-01 | 公開日 | 2023-06-21 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
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