PDB: 621 件ウェブページステータス検索Chemie searchBIRD

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5NWI	14-3-3c in complex with CPP 分子名称: 14-3-3 c-1 protein, ACETATE ION, Potassium channel KAT1 著者 Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. 登録日 2017-05-06 公開日 2017-11-22 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell, 29, 2017
5OM0	CH2 chimera of human 14-3-3 sigma with the Gli1 phosphopeptide around Ser640 分子名称: 14-3-3 protein sigma,Zinc finger protein GLI1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION 著者 Sluchanko, N.N, Tugaeva, K.V, Greive, S.J, Antson, A.A. 登録日 2017-07-28 公開日 2017-10-11 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners. Sci Rep, 7, 2017
5NWJ	14-3-3c in complex with CPP7 分子名称: 14-3-3-like protein C, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. 登録日 2017-05-06 公開日 2017-11-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell, 29, 2017
5NWK	14-3-3c in complex with CPP and fusicoccin 分子名称: 14-3-3 c-1 protein, FUSICOCCIN, PHOSPHOSERINE, ... 著者 Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. 登録日 2017-05-06 公開日 2017-11-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell, 29, 2017
5OEG	Molecular tweezers modulate 14-3-3 protein-protein interactions 分子名称: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein sigma, CHLORIDE ION 著者 Bier, D, Ottmann, C. 登録日 2017-07-07 公開日 2017-07-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Molecular tweezers modulate 14-3-3 protein-protein interactions. Nat Chem, 5, 2013
7D8H	CRTC1 pSer64 peptide in complex with 14-3-3 zeta 分子名称: 14-3-3 protein zeta/delta, CRTC1 pSer64 peptide 著者 Chen, H, Zhang, H, Xiang, S. 登録日 2020-10-08 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Structural Insights into the Interaction Between CRTCs and 14-3-3. J.Mol.Biol., 433, 2021
7D9V	CRTC1 pSer245 peptide in complex with 14-3-3 zeta 分子名称: 14-3-3 protein zeta/delta, CRTC1 pSer245 peptide, GLYCEROL 著者 Chen, H, Zhang, H, Xiang, S. 登録日 2020-10-14 公開日 2021-02-24 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structural Insights into the Interaction Between CRTCs and 14-3-3. J.Mol.Biol., 433, 2021
7D8P	CRTC1 pSer151 peptide in complex with 14-3-3 zeta 分子名称: 14-3-3 protein zeta/delta, CRTC1 pSer151 peptide, GLYCEROL 著者 Chen, H, Zhang, H, Xiang, S. 登録日 2020-10-08 公開日 2021-02-24 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Insights into the Interaction Between CRTCs and 14-3-3. J.Mol.Biol., 433, 2021
7EXE	Crystal structure of mouse 14-3-3zeta in complex with doubly phosphorylated ADAM22 peptide 分子名称: 14-3-3 protein zeta/delta, Disintegrin and metalloproteinase domain-containing protein 22 著者 Yan, L, Okatsu, K, Fukai, S. 登録日 2021-05-27 公開日 2021-11-24 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 LGI1-ADAM22 levels regulate seizure thresholds through 14-3-3 in mice Cell Rep, 2021
7BIW	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-187 分子名称: 14-3-3 protein sigma, 4-(3,4-dihydro-2~{H}-quinoxalin-1-ylsulfonyl)benzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-01-13 公開日 2021-09-15 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7BJB	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-044 分子名称: 14-3-3 protein sigma, 4-(4-methylphenyl)sulfonylmorpholine, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-01-14 公開日 2021-09-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
6TLG	Ligand-free state of human 14-3-3 sigma isoform 分子名称: 14-3-3 protein sigma, DI(HYDROXYETHYL)ETHER, SULFATE ION 著者 Tassone, G, Pozzi, C, Mangani, S. 登録日 2019-12-02 公開日 2020-03-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction. Acs Chem.Biol., 15, 2020
6T5F	Human 14-3-3 sigma fused to the StARD1 peptide including phosphoserine-195 分子名称: 14-3-3 protein sigma, StARD1 peptide 著者 Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A. 登録日 2019-10-16 公開日 2020-11-18 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Molecular basis for the recognition of steroidogenic acute regulatory protein by the 14-3-3 protein family. Febs J., 287, 2020
6T80	Human 14-3-3 sigma fused to the AANAT peptide including phosphoserine-205 分子名称: 14-3-3 protein sigma, AANAT peptide 著者 Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A. 登録日 2019-10-23 公開日 2020-11-18 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Human 14-3-3 sigma fused to the AANAT peptide including phosphoserine-205 To Be Published
6T5H	Human 14-3-3 sigma fused to the StARD1 peptide including phosphoserine-57 分子名称: 14-3-3 protein sigma,Steroidogenic acute regulatory protein, mitochondrial, IMIDAZOLE, ... 著者 Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A. 登録日 2019-10-16 公開日 2020-11-18 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Molecular basis for the recognition of steroidogenic acute regulatory protein by the 14-3-3 protein family. Febs J., 287, 2020
6A5Q	Structure of 14-3-3 beta in complex with TFEB 14-3-3 binding motif 分子名称: 14-3-3 protein beta/alpha, MALONIC ACID, TFEB pS211-peptide 著者 Xu, Y, Ren, J.Q, Feng, W. 登録日 2018-06-25 公開日 2019-02-13 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization. Autophagy, 15, 2019
6TJM	Crystal structure of an Estrogen Receptor alpha 8-mer phosphopeptide in complex with 14-3-3sigma stabilized by Pyrrolidone1 分子名称: 14-3-3 protein sigma, 5-[(2~{R})-2-(4-nitrophenyl)-4-oxidanyl-5-oxidanylidene-3-(phenylcarbonyl)-2~{H}-pyrrol-1-yl]-2-oxidanyl-benzoic acid, C-terminal phosphopeptide of human estrogen receptor alpha, ... 著者 Andrei, S.A, Bosica, F, Ottmann, C, O'Mahony, G. 登録日 2019-11-26 公開日 2020-04-29 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Design of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization. Chemistry, 26, 2020
6TLF	human 14-3-3 sigma isoform in complex with IMP 分子名称: 14-3-3 protein sigma, INOSINIC ACID, SULFATE ION 著者 Tassone, G, Pozzi, C, Mangani, S. 登録日 2019-12-02 公開日 2020-03-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction. Acs Chem.Biol., 15, 2020
6TM7	Human 14-3-3 sigma isoform in complex with PLP 分子名称: 14-3-3 protein sigma, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION 著者 Tassone, G, Pozzi, C, Mangani, S. 登録日 2019-12-03 公開日 2020-03-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction. Acs Chem.Biol., 15, 2020
6A5S	Structure of 14-3-3 gamma in complex with TFEB 14-3-3 binding motif 分子名称: 14-3-3 protein gamma, MAGNESIUM ION, SODIUM ION, ... 著者 Xu, Y, Ren, J.Q, Feng, W. 登録日 2018-06-25 公開日 2019-02-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization. Autophagy, 15, 2019
6BD2	Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and S366 分子名称: 1,2-ETHANEDIOL, 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, ... 著者 Kast, D.J, Dominguez, R. 登録日 2017-10-20 公開日 2018-10-24 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Mechanism of IRSp53 inhibition by 14-3-3. Nat Commun, 10, 2019
6BCY	Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T360 分子名称: 14-3-3 protein theta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, ... 著者 Kast, D.J, Dominguez, R. 登録日 2017-10-20 公開日 2018-10-24 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Mechanism of IRSp53 inhibition by 14-3-3. Nat Commun, 10, 2019
6BD1	Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at S366 分子名称: 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, Insulin receptor substrate protein of 53 kDa, ... 著者 Kast, D.J, Dominguez, R. 登録日 2017-10-20 公開日 2018-10-24 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Mechanism of IRSp53 inhibition by 14-3-3. Nat Commun, 10, 2019
6TWZ	14-3-3 sigma complexed with a phosphorylated 16E6 peptide 分子名称: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D(-)-TARTARIC ACID, ... 著者 Gogl, G, Cousido-Siah, A, Sluchanko, N.N, Trave, G. 登録日 2020-01-13 公開日 2020-05-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study. Structure, 28, 2020
6BYL	Structure of 14-3-3 gamma bound to O-GlcNAcylated thr peptide 分子名称: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, TSASTTVPVTTATTTTTSTW O-GlcNac peptide 著者 Schumacher, M.A. 登録日 2017-12-20 公開日 2018-05-09 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins. Proc.Natl.Acad.Sci.USA, 115, 2018

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