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5W5A
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Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c)
分子名称: CHLORIDE ION, HTH-type transcriptional regulator Cmr, SULFATE ION
著者Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A.
登録日2017-06-14
公開日2017-12-13
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria.
Nucleic Acids Res., 46, 2018
5W5B
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Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c), truncated construct
分子名称: CHLORIDE ION, HTH-type transcriptional regulator Cmr
著者Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A.
登録日2017-06-14
公開日2017-12-13
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria.
Nucleic Acids Res., 46, 2018
4RZ7
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BU of 4rz7 by Molmil
Crystal Structure of PVX_084705 with bound PCI32765
分子名称: 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, UNKNOWN ATOM OR ION, cGMP-dependent protein kinase, ...
著者Jiang, D.Q, Tempel, W, Loppnau, P, Graslund, S, He, H, Seitova, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Hutchinson, A, El Bakkouri, M, Amani, M, Structural Genomics Consortium (SGC)
登録日2014-12-18
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Crystal Structure of PVX_084705 with bound PCI32765
To be Published
1CGP
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CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX + ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*GP*CP*GP*AP*AP*AP*AP*GP*TP*GP*TP*GP*AP*CP*AP*TP*AP*T)-3'), DNA (5'-D(*GP*TP*CP*AP*CP*AP*CP*TP*TP*TP*TP*CP*G)-3'), ...
著者Schultz, S.C, Shields, G.C, Steitz, T.A.
登録日1991-08-12
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a CAP-DNA complex: the DNA is bent by 90 degrees.
Science, 253, 1991
4X6R
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An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Zhang, P, Ye, F, Bastidas, A.C, Kornev, A.P, Ginsberg, M.H, Wu, J, Taylor, S.S.
登録日2014-12-09
公開日2015-07-22
最終更新日2020-06-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.
Structure, 23, 2015
4X6Q
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BU of 4x6q by Molmil
An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes
分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Zhang, P, Ye, F, Bastidas, A.C, Kornev, A.P, Ginsberg, M.H, Taylor, S.S.
登録日2014-12-08
公開日2015-07-22
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.
Structure, 23, 2015
4WBB
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Single Turnover Autophosphorylation Cycle of the PKA RIIb Holoenzyme
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ...
著者Zhang, P, Knape, M.J, Ahuja, L.G, Keshwani, M.M, King, C.C, Sastri, M, Herberg, F.W, Taylor, S.S.
登録日2014-09-02
公開日2015-05-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Single Turnover Autophosphorylation Cycle of the PKA RII beta Holoenzyme.
Plos Biol., 13, 2015
1G6N
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BU of 1g6n by Molmil
2.1 ANGSTROM STRUCTURE OF CAP-CAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CATABOLITE GENE ACTIVATOR PROTEIN
著者Passner, J.M, Schultz, S.C, Steitz, T.A.
登録日2000-11-07
公開日2000-12-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Modeling the cAMP-induced allosteric transition using the crystal structure of CAP-cAMP at 2.1 A resolution.
J.Mol.Biol., 304, 2000
1HW5
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THE CAP/CRP VARIANT T127L/S128A
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CATABOLITE GENE ACTIVATOR
著者Chu, S.Y, Tordova, M, Gilliland, G.L, Gorshkova, I, Shi, Y.
登録日2001-01-09
公開日2001-01-17
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献The structure of the T127L/S128A mutant of cAMP receptor protein facilitates promoter site binding
J.Biol.Chem., 276, 2001
1I6X
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STRUCTURE OF A STAR MUTANT CRP-CAMP AT 2.2 A
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CATABOLITE GENE ACTIVATOR PROTEIN
著者White, M.A, Lee, J.C, Fox, R.O.
登録日2001-03-06
公開日2003-06-17
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The effect of the D53H point mutation on the macroscopic motions of E. coli Cyclic AMP Receptor Protein
To be Published
8BX7
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BU of 8bx7 by Molmil
Structure of the rod CNG channel bound to calmodulin
分子名称: Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1, calmodulin-1
著者Marino, J.
登録日2022-12-08
公開日2023-04-12
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel.
Proc.Natl.Acad.Sci.USA, 120, 2023
7CAL
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BU of 7cal by Molmil
Cryo-EM Structure of the Hyperpolarization-Activated Inwardly Rectifying Potassium Channel KAT1 from Arabidopsis
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Potassium channel KAT1
著者Li, S.Y, Yang, F, Sun, D.M, Zhang, Y, Zhang, M.G, Zhou, P, Liu, S.L, Zhang, Y.N, Zhang, L.H, Tian, C.L.
登録日2020-06-09
公開日2020-07-29
最終更新日2020-11-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis.
Cell Res., 30, 2020
2BYV
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BU of 2byv by Molmil
Structure of the cAMP responsive exchange factor Epac2 in its auto- inhibited state
分子名称: RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4
著者Rehmann, H, Wittinghofer, A, Bos, J.L.
登録日2005-08-08
公開日2006-02-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the Cyclic-AMP Responsive Exchange Factor Epac2 in its Auto-Inhibited State
Nature, 439, 2006
2CGP
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BU of 2cgp by Molmil
CATABOLITE GENE ACTIVATOR PROTEIN/DNA COMPLEX, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*AP*TP*TP*AP*AP*TP*GP*TP*GP*AP*CP*AP*TP*AP*T)-3'), DNA (5'-D(*GP*TP*CP*AP*CP*AP*TP*TP*AP*AP*T)-3'), ...
著者Passner, J.M, Steitz, T.A.
登録日1997-01-31
公開日1998-02-04
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of a CAP-DNA complex having two cAMP molecules bound to each monomer.
Proc.Natl.Acad.Sci.USA, 94, 1997
8EM8
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Co-crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium falciparum in complex with RY-1-165
分子名称: UNKNOWN ATOM OR ION, [(3R)-3-{[(4M)-4-(4-cyclopropyl-2-phenyl-1H-imidazol-1-yl)pyrimidin-2-yl]amino}pyrrolidin-1-yl](1,3-thiazol-2-yl)methanone, cGMP-dependent protein kinase, ...
著者Hutchinson, A, Dong, A, Seitova, A, Bhanot, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC)
登録日2022-09-27
公開日2022-11-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Co-crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium falciparum in complex with RY-1-165
To Be Published
8EP1
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Eag Kv channel with voltage sensor in the down conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EP0
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Eag Kv channel with voltage sensor in the intermediate conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EOW
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Eag Kv channel with voltage sensor in the up conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
7FF9
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Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ...
著者Chew, B.L.A, Luo, D.
登録日2021-07-23
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
To Be Published
7FF8
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Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ...
著者Chew, B.L.A, Luo, D.
登録日2021-07-22
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
To Be Published
7FEW
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BU of 7few by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cAMP-activated global transcriptional regulator Vfr
著者Chew, B.L.A, Luo, D.
登録日2021-07-22
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
7FF0
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Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GOLD ION, SULFATE ION, ...
著者Chew, B.L.A, Luo, D.
登録日2021-07-22
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
2FMY
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CO-dependent transcription factor CooA from Carboxydothermus hydrogenoformans (Imidazole-bound form)
分子名称: IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, carbon monoxide oxidation system transcription regulator CooA-1
著者Higuchi, Y, Komori, H.
登録日2006-01-10
公開日2007-01-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of CO-sensing Transcription Activator CooA Bound to Exogenous Ligand Imidazole
J.Mol.Biol., 367, 2007
2GAU
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BU of 2gau by Molmil
Crystal structure of transcriptional regulator, Crp/Fnr family from Porphyromonas gingivalis (APC80792), Structural genomics, MCSG
分子名称: transcriptional regulator, Crp/Fnr family
著者Rotella, F.J, Zhang, R.G, Mulligan, R, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-03-09
公開日2006-04-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The 1.9-A crystal structure of transcriptional regulator, Crp/Fnr family from Porphyromonas gingivalis
To be Published
6HQ5
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Structure of EAL Enzyme Bd1971 - cAMP and cyclic-di-GMP bound form
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CALCIUM ION, ...
著者Lovering, A.L, Cadby, I.T.
登録日2018-09-24
公開日2019-07-31
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Nucleotide signaling pathway convergence in a cAMP-sensing bacterial c-di-GMP phosphodiesterase.
Embo J., 38, 2019

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