PDB: 446 件ウェブページステータス検索Chemie searchBIRD

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3SUH	Crystal structure of THF riboswitch, bound with 5-formyl-THF 分子名称: N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, Riboswitch, SODIUM ION 著者 Huang, L, Serganov, A, Patel, D.J. 登録日 2011-07-11 公開日 2011-09-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch. Proc.Natl.Acad.Sci.USA, 108, 2011
4FEL	Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine 分子名称: ACETATE ION, COBALT HEXAMMINE(III), HYPOXANTHINE, ... 著者 Stoddard, C.D, Trausch, J.J, Widmann, J, Marcano, J, Knight, R, Batey, R.T. 登録日 2012-05-30 公開日 2013-02-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch. J.Mol.Biol., 425, 2013
4FEJ	Crystal structure of the A24U mutant xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine 分子名称: A24U mutant of the B. subtilis xpt-pbuX guanine riboswitch aptamer domain, ACETATE ION, COBALT HEXAMMINE(III), ... 著者 Stoddard, C.D, Trausch, J.J, Widmann, J, Marcano, J, Knight, R, Batey, R.T. 登録日 2012-05-30 公開日 2013-02-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch. J.Mol.Biol., 425, 2013
4FEP	Crystal structure of the A24U/U25A/A46G/C74U mutant xpt-pbuX guanine riboswitch aptamer domain in complex with 2,6-diaminopurine 分子名称: 9H-PURINE-2,6-DIAMINE, A24U/U25A/A46G/C74U mutant of the B. subtilis xpt-pbuX guanine riboswitch aptamer domain, COBALT HEXAMMINE(III) 著者 Stoddard, C.D, Trausch, J.J, Widmann, J, Marcano, J, Knight, R, Batey, R.T. 登録日 2012-05-30 公開日 2013-02-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch. J.Mol.Biol., 425, 2013
4FEO	Crystal structure of the AU25A/A46G/C74U mutant xpt-pbuX guanine riboswitch aptamer domain in complex with 2,6-diaminopurine 分子名称: 9H-PURINE-2,6-DIAMINE, COBALT HEXAMMINE(III), U25A/A46G/C74U mutant of the B. subtilis xpt-pbuX guanine riboswitch aptamer domain 著者 Stoddard, C.D, Trausch, J.J, Widmann, J, Marcano, J, Knight, R, Batey, R.T. 登録日 2012-05-30 公開日 2013-02-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch. J.Mol.Biol., 425, 2013
4FEN	Crystal structure of the A24U/U25A/A46G mutant xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine 分子名称: A24U/U25A/A46G mutant of the B. subtilis xpt-pbuX guanine riboswitch aptamer domain, ACETATE ION, COBALT HEXAMMINE(III), ... 著者 Stoddard, C.D, Trausch, J.J, Widmann, J, Marcano, J, Knight, R, Batey, R.T. 登録日 2012-05-30 公開日 2013-02-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch. J.Mol.Biol., 425, 2013
4NYC	Crystal structure of the E. coli thiM riboswitch in complex with thieno[2,3-b]pyrazin-7-amine 分子名称: MAGNESIUM ION, MANGANESE (II) ION, thiM TPP riboswitch, ... 著者 Warner, K.D, Homan, P, Weeks, K.M, Smith, A.G, Abell, C, Ferre-D'Amare, A.R. 登録日 2013-12-10 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Validating Fragment-Based Drug Discovery for Biological RNAs: Lead Fragments Bind and Remodel the TPP Riboswitch Specifically. Chem.Biol., 21, 2014
4NYB	Crystal structure of the E. coli thiM riboswitch in complex with (4-(1,2,3-thiadiazol-4-yl)phenyl)methanamine 分子名称: 1-[4-(1,2,3-thiadiazol-4-yl)phenyl]methanamine, MAGNESIUM ION, MANGANESE (II) ION, ... 著者 Warner, K.D, Homan, P, Weeks, K.M, Smith, A.G, Abell, C, Ferre-D'Amare, A.R. 登録日 2013-12-10 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Validating Fragment-Based Drug Discovery for Biological RNAs: Lead Fragments Bind and Remodel the TPP Riboswitch Specifically. Chem.Biol., 21, 2014
4NYG	Crystal structure of the E. coli thiM riboswitch in complex with thiamine 分子名称: 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, MAGNESIUM ION, thiM TPP riboswitch 著者 Warner, K.D, Homan, P, Weeks, K.M, Smith, A.G, Abell, C, Ferre-D'Amare, A.R. 登録日 2013-12-10 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Validating Fragment-Based Drug Discovery for Biological RNAs: Lead Fragments Bind and Remodel the TPP Riboswitch Specifically. Chem.Biol., 21, 2014
4ENC	Crystal structure of fluoride riboswitch 分子名称: FLUORIDE ION, Fluoride riboswitch, MAGNESIUM ION, ... 著者 Ren, A.M, Rajashankar, K.R, Patel, D.J. 登録日 2012-04-12 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.272 Å) 主引用文献 Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch. Nature, 486, 2012
4NYD	Crystal structure of the E. coli thiM riboswitch in complex with hypoxanthine 分子名称: HYPOXANTHINE, MAGNESIUM ION, MANGANESE (II) ION, ... 著者 Warner, K.D, Homan, P, Weeks, K.M, Smith, A.G, Abell, C, Ferre-D'Amare, A.R. 登録日 2013-12-10 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Validating Fragment-Based Drug Discovery for Biological RNAs: Lead Fragments Bind and Remodel the TPP Riboswitch Specifically. Chem.Biol., 21, 2014
4NYA	Crystal structure of the E. coli thiM riboswitch in complex with 5-(azidomethyl)-2-methylpyrimidin-4-amine 分子名称: 5-(azidomethyl)-2-methylpyrimidin-4-amine, MAGNESIUM ION, thiM TPP riboswitch 著者 Warner, K.D, Homan, P, Weeks, K.M, Smith, A.G, Abell, C, Ferre-D'Amare, A.R. 登録日 2013-12-10 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Validating Fragment-Based Drug Discovery for Biological RNAs: Lead Fragments Bind and Remodel the TPP Riboswitch Specifically. Chem.Biol., 21, 2014
4EN5	Crystal structure of fluoride riboswitch, Tl-Acetate soaked 分子名称: FLUORIDE ION, Fluoride riboswitch, MAGNESIUM ION, ... 著者 Ren, A.M, Rajashankar, K.R, Patel, D.J. 登録日 2012-04-12 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.957 Å) 主引用文献 Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch. Nature, 486, 2012
4ENA	Crystal structure of fluoride riboswitch, soaked in Cs+ 分子名称: CESIUM ION, FLUORIDE ION, Fluoride riboswitch, ... 著者 Ren, A.M, Rajashankar, K.R, Patel, D.J. 登録日 2012-04-12 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch. Nature, 486, 2012
4ENB	Crystal structure of fluoride riboswitch, bound to Iridium 分子名称: FLUORIDE ION, Fluoride riboswitch, IRIDIUM HEXAMMINE ION, ... 著者 Ren, A.M, Rajashankar, K.R, Patel, D.J. 登録日 2012-04-12 公開日 2012-05-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch. Nature, 486, 2012
4LVZ	Structure of the THF riboswitch bound to 2,6-diaminopurine 分子名称: 9H-PURINE-2,6-DIAMINE, THF riboswitch 著者 Trausch, J.J, Batey, R.T. 登録日 2013-07-26 公開日 2014-03-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch. Chem.Biol., 21, 2014
4LVY	Structure of the THF riboswitch bound to pemetrexed 分子名称: 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, THF riboswitch 著者 Trausch, J.J, Batey, R.T. 登録日 2013-07-26 公開日 2014-03-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch. Chem.Biol., 21, 2014
4LW0	Structure of the THF riboswitch bound to adenine 分子名称: ADENINE, THF riboswitch 著者 Trausch, J.J, Batey, R.T. 登録日 2013-07-26 公開日 2014-03-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.889 Å) 主引用文献 A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch. Chem.Biol., 21, 2014
4LVW	Structure of the THF riboswitch bound to 7-deazaguanine 分子名称: 7-DEAZAGUANINE, THF riboswitch 著者 Trausch, J.J, Batey, R.T. 登録日 2013-07-26 公開日 2014-03-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.768 Å) 主引用文献 A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch. Chem.Biol., 21, 2014
4LVX	Structure of the THF riboswitch bound to tetrahydrobiopterin 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, THF riboswitch 著者 Trausch, J.J, Batey, R.T. 登録日 2013-07-26 公開日 2014-03-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch. Chem.Biol., 21, 2014
4LVV	Structure of the THF riboswitch 分子名称: N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, THF riboswitch 著者 Trausch, J.J, Batey, R.T. 登録日 2013-07-26 公開日 2014-03-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch. Chem.Biol., 21, 2014
4RUM	Crystal structure of the NiCo transition-metal riboswitch bound to cobalt 分子名称: COBALT (II) ION, GLYCEROL, MAGNESIUM ION, ... 著者 Ramesh, A, Winkler, W.C. 登録日 2014-11-21 公開日 2015-04-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6426 Å) 主引用文献 Bacterial riboswitches cooperatively bind Ni(2+) or Co(2+) ions and control expression of heavy metal transporters. Mol.Cell, 57, 2015
6DLQ	PRPP Riboswitch bound to PRPP, manganese chloride soaked structure 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MANGANESE (II) ION, POTASSIUM ION, ... 著者 Peselis, A, Serganov, A. 登録日 2018-06-02 公開日 2018-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands. Nat. Chem. Biol., 14, 2018
6DLT	PRPP Riboswitch bound to PRPP, native structure 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, PRPP Riboswitch, ... 著者 Peselis, A, Serganov, A. 登録日 2018-06-02 公開日 2018-11-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands. Nat. Chem. Biol., 14, 2018
6DLS	PRPP Riboswitch bound to PRPP, thallium acetate soaked structure 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, PRPP Riboswitch, ... 著者 Peselis, A, Serganov, A. 登録日 2018-06-02 公開日 2018-11-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.885 Å) 主引用文献 ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands. Nat. Chem. Biol., 14, 2018

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