4LVX
Structure of the THF riboswitch bound to tetrahydrobiopterin
Summary for 4LVX
Entry DOI | 10.2210/pdb4lvx/pdb |
Related | 3SD3 4LVV 4LVW 4LVY 4LVZ 4LW0 |
Descriptor | THF riboswitch, 5,6,7,8-TETRAHYDROBIOPTERIN (3 entities in total) |
Functional Keywords | aptamers, nucleotide, bacillus subtilis, bacterial proteins, base sequence, binding sites, calorimetry, folic acid, gene expression regulation, bacterial, guanine, leucovorin, ligands, magnesium, molecular sequence data, nucleic acid conformation, point mutation, protein binding, protein structure, secondary, rna, riboswitch, s-adenosylmethionine, streptococcus mutans, terminator regions, genetic, tetrahydrofolates, thermodynamics, transcription, three-way junction, pseudoknot, regulation, ncrna, tetrahydrobiopterin binding, mrna |
Total number of polymer chains | 1 |
Total formula weight | 29331.64 |
Authors | Trausch, J.J.,Batey, R.T. (deposition date: 2013-07-26, release date: 2014-03-19, Last modification date: 2024-02-28) |
Primary citation | Trausch, J.J.,Batey, R.T. A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch. Chem.Biol., 21:205-216, 2014 Cited by PubMed: 24388757DOI: 10.1016/j.chembiol.2013.11.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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