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8R09
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BU of 8r09 by Molmil
Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-31
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QZS
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BU of 8qzs by Molmil
Cryo-EM structure of the cross-exon B-like complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Microfibrillar-associated protein 1, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-29
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8R0A
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BU of 8r0a by Molmil
Cryo-EM structure of the cross-exon pre-B+5'ss complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-31
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8R08
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BU of 8r08 by Molmil
Cryo-EM structure of the cross-exon pre-B+AMPPNP complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-31
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8R0B
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BU of 8r0b by Molmil
Cryo-EM structure of the cross-exon pre-B+ATP complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-31
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8RM5
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BU of 8rm5 by Molmil
Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'SS oligo, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2024-01-05
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QXD
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BU of 8qxd by Molmil
Cryo-EM structure of the cross-exon pre-B complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-24
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (9.6 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8Q7N
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BU of 8q7n by Molmil
cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R.
登録日2023-08-16
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献New insights into the functions of B complex proteins revealed by cryo-EM of dimerized spliceosomes
To Be Published
5ZWN
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BU of 5zwn by Molmil
Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom (Part II: U1 snRNP region)
分子名称: 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Pre-mRNA-splicing ATP-dependent RNA helicase PRP28, ...
著者Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y.
登録日2018-05-16
公開日2018-08-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
8QOZ
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BU of 8qoz by Molmil
Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss RNA oligo, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-09-29
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QPE
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BU of 8qpe by Molmil
Cryo-EM Structure of Pre-B-like Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Microfibrillar-associated protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-01
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QPA
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BU of 8qpa by Molmil
Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-01
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QPB
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BU of 8qpb by Molmil
Cryo-EM Structure of Pre-B+ATP Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-01
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QP9
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BU of 8qp9 by Molmil
Cryo-EM Structure of Pre-B+AMPPNP Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Pre-mRNA-processing factor 6, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-09-30
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QPK
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BU of 8qpk by Molmil
Cryo-EM Structure of Pre-B+5'ss Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-02
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
5GAM
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BU of 5gam by Molmil
Foot region of the yeast spliceosomal U4/U6.U5 tri-snRNP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, ...
著者Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K.
登録日2015-12-15
公開日2016-02-03
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Angstrom resolution
Nature, 530, 2016
8QP8
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BU of 8qp8 by Molmil
Cryo-EM Structure of Pre-B Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Pre-mRNA-processing factor 6, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-09-30
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
3ENB
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BU of 3enb by Molmil
Crystal Structure of PRP8 core domain IV
分子名称: Pre-mRNA-processing-splicing factor 8
著者Schellenberg, M.J, Ritchie, D.B, MacMillan, A.M.
登録日2008-09-25
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural elucidation of a PRP8 core domain from the heart of the spliceosome.
Nat.Struct.Mol.Biol., 15, 2008
5GAO
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BU of 5gao by Molmil
Head region of the yeast spliceosomal U4/U6.U5 tri-snRNP
分子名称: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2, Saccharomyces cerevisiae strain UOA_M2 chromosome 5 sequence, ...
著者Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K.
登録日2015-12-15
公開日2016-01-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
1LMV
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BU of 1lmv by Molmil
Solution structure of the unmodified U2 snRNA-intron branch site helix from S. cerevisiae
分子名称: 5'-R(*GP*GP*UP*GP*UP*AP*GP*UP*A)-3', 5'-R(*UP*AP*CP*UP*AP*AP*CP*AP*CP*C)-3'
著者Newby, M.I, Greenbaum, N.L.
登録日2002-05-02
公開日2002-11-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Sculpting of the Spliceosomal Branch Site Recognition Motif by a Conserved Pseudouridine
Nat.Struct.Biol., 9, 2002
3E9L
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BU of 3e9l by Molmil
Crystal Structure of Human Prp8, Residues 1755-2016
分子名称: CHLORIDE ION, Pre-mRNA-processing-splicing factor 8, SODIUM ION
著者Pena, V, Rozov, A, Wahl, M.C.
登録日2008-08-22
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and function of an RNase H domain at the heart of the spliceosome.
Embo J., 27, 2008
3E9O
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BU of 3e9o by Molmil
Crystal Structure of Yeast Prp8, Residues 1836-2092
分子名称: Pre-mRNA-splicing factor 8
著者Pena, V, Rozov, A, Wahl, M.C.
登録日2008-08-22
公開日2008-10-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and function of an RNase H domain at the heart of the spliceosome.
Embo J., 27, 2008
3E9P
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BU of 3e9p by Molmil
Crystal Structure of Yeast Prp8, Residues 1827-2092
分子名称: Pre-mRNA-splicing factor 8
著者Pena, V, Rozov, A, Wahl, M.C.
登録日2008-08-22
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and function of an RNase H domain at the heart of the spliceosome.
Embo J., 27, 2008
6NQI
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BU of 6nqi by Molmil
Prp8 RH domain from C. merolae
分子名称: BETA-MERCAPTOETHANOL, Pre-mRNA splicing factor PRP8
著者Garside, E.L, MacMillan, A.M.
登録日2019-01-21
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Prp8 in a Reduced Spliceosome Lacks a Conserved Toggle that Correlates with Splicing Complexity across Diverse Taxa.
J.Mol.Biol., 431, 2019
4BGD
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BU of 4bgd by Molmil
Crystal structure of Brr2 in complex with the Jab1/MPN domain of Prp8
分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Nguyen, T.H.D, Li, J, Nagai, K.
登録日2013-03-25
公開日2013-05-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis of Brr2-Prp8 Interactions and Implications for U5 Snrnp Biogenesis and the Spliceosome Active Site
Structure, 21, 2013

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件を2024-07-17に公開中

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