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8R08
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BU of 8r08 by Molmil
Cryo-EM structure of the cross-exon pre-B+AMPPNP complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-31
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QZS
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BU of 8qzs by Molmil
Cryo-EM structure of the cross-exon B-like complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Microfibrillar-associated protein 1, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-29
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
3SIU
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BU of 3siu by Molmil
Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, monomeric form
分子名称: NHP2-like protein 1, SULFATE ION, U4/U6 small nuclear ribonucleoprotein Prp31, ...
著者Liu, S, Ghalei, H, Luhrmann, R, Wahl, M.C.
登録日2011-06-20
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.626 Å)
主引用文献Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31.
Rna, 17, 2011
8QPE
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BU of 8qpe by Molmil
Cryo-EM Structure of Pre-B-like Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Microfibrillar-associated protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-01
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
5GAM
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BU of 5gam by Molmil
Foot region of the yeast spliceosomal U4/U6.U5 tri-snRNP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, ...
著者Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K.
登録日2015-12-15
公開日2016-02-03
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Angstrom resolution
Nature, 530, 2016
7Q4P
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BU of 7q4p by Molmil
U2 snRNP after ATP-dependent remodelling
分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, Splicing factor 3A subunit 3, ...
著者Tholen, J, Galej, W.P.
登録日2021-11-01
公開日2022-03-30
最終更新日2022-04-06
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Structural basis of branch site recognition by the human spliceosome.
Science, 375, 2022
8QXD
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BU of 8qxd by Molmil
Cryo-EM structure of the cross-exon pre-B complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-24
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (9.6 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
7Q3L
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BU of 7q3l by Molmil
Human 17S U2 snRNP 5' domain
分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ...
著者Tholen, J, Galej, W.P.
登録日2021-10-28
公開日2022-03-30
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structural basis of branch site recognition by the human spliceosome.
Science, 375, 2022
8QPK
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BU of 8qpk by Molmil
Cryo-EM Structure of Pre-B+5'ss Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-02
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QPA
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BU of 8qpa by Molmil
Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-01
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QOZ
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BU of 8qoz by Molmil
Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss RNA oligo, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-09-29
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QP8
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BU of 8qp8 by Molmil
Cryo-EM Structure of Pre-B Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Pre-mRNA-processing factor 6, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-09-30
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QPB
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BU of 8qpb by Molmil
Cryo-EM Structure of Pre-B+ATP Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-01
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QP9
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BU of 8qp9 by Molmil
Cryo-EM Structure of Pre-B+AMPPNP Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Pre-mRNA-processing factor 6, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-09-30
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
5ZWN
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BU of 5zwn by Molmil
Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom (Part II: U1 snRNP region)
分子名称: 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Pre-mRNA-splicing ATP-dependent RNA helicase PRP28, ...
著者Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y.
登録日2018-05-16
公開日2018-08-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
5GAO
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BU of 5gao by Molmil
Head region of the yeast spliceosomal U4/U6.U5 tri-snRNP
分子名称: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2, Saccharomyces cerevisiae strain UOA_M2 chromosome 5 sequence, ...
著者Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K.
登録日2015-12-15
公開日2016-01-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
6QW6
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BU of 6qw6 by Molmil
Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Charenton, C, Wilkinson, M.E, Nagai, K.
登録日2019-03-05
公開日2019-04-17
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
6NQI
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BU of 6nqi by Molmil
Prp8 RH domain from C. merolae
分子名称: BETA-MERCAPTOETHANOL, Pre-mRNA splicing factor PRP8
著者Garside, E.L, MacMillan, A.M.
登録日2019-01-21
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Prp8 in a Reduced Spliceosome Lacks a Conserved Toggle that Correlates with Splicing Complexity across Diverse Taxa.
J.Mol.Biol., 431, 2019
5M5P
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BU of 5m5p by Molmil
S. cerevisiae spliceosomal helicase Brr2 (271-end) in complex with the Jab/MPN domain of S. cerevisiae Prp8
分子名称: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2
著者Becke, C, Absmeier, E, Wollenhaupt, J, Santos, K.F, Wahl, M.C.
登録日2016-10-22
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2.
Cell Cycle, 16, 2017
4I43
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BU of 4i43 by Molmil
Crystal structure of Prp8:Aar2 complex
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Galej, W.P, Oubridge, C, Newman, A.J, Nagai, K.
登録日2012-11-27
公開日2013-01-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Prp8 reveals active site cavity of the spliceosome.
Nature, 493, 2013
4BWS
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BU of 4bws by Molmil
Crystal structure of the heterotrimer of PQBP1, U5-15kD and U5-52kD.
分子名称: CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2, POLYGLUTAMINE-BINDING PROTEIN 1, THIOREDOXIN-LIKE PROTEIN 4A
著者Mizuguchi, M, Obita, T, Serita, T, Kojima, R, Morimoto, T, Nabeshima, Y, Okazawa, H.
登録日2013-07-04
公開日2014-04-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd.
Nat.Commun., 5, 2014
4BWQ
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BU of 4bwq by Molmil
Crystal structure of U5-15kD in a complex with PQBP1
分子名称: POLYGLUTAMINE-BINDING PROTEIN 1, THIOREDOXIN-LIKE PROTEIN 4A
著者Mizuguchi, M, Obita, T, Serita, T, Kojima, R, Morimoto, T, Nabeshima, Y, Okazawa, H.
登録日2013-07-04
公開日2014-04-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd.
Nat.Commun., 5, 2014
1ZWZ
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BU of 1zwz by Molmil
Structural comparison of Yeast snoRNP and splicesomal protein snu13p with its homologs
分子名称: Snu13p
著者Oruganti, S, Zhang, Y, Li, H.
登録日2005-06-06
公開日2006-05-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural comparison of yeast snoRNP and spliceosomal protein Snu13p with its homologs
Biochem.Biophys.Res.Commun., 333, 2005
3ENB
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BU of 3enb by Molmil
Crystal Structure of PRP8 core domain IV
分子名称: Pre-mRNA-processing-splicing factor 8
著者Schellenberg, M.J, Ritchie, D.B, MacMillan, A.M.
登録日2008-09-25
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural elucidation of a PRP8 core domain from the heart of the spliceosome.
Nat.Struct.Mol.Biol., 15, 2008
4RVQ
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BU of 4rvq by Molmil
PWI-like domain of Chaetomium thermophilum Brr2
分子名称: 1,2-ETHANEDIOL, Pre-mRNA splicing helicase-like protein, SULFATE ION
著者Absmeier, E, Rosenberger, L, Santos, K.F, Becke, C, Wahl, M.C.
登録日2014-11-27
公開日2015-04-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.135 Å)
主引用文献A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein.
Acta Crystallogr.,Sect.D, 71, 2015

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