PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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3CJ4	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments 分子名称: 4-[(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)amino]-4-oxobutanoic acid, NICKEL (II) ION, RNA-directed RNA polymerase 著者 Antonysamy, s.s. 登録日 2008-03-12 公開日 2008-04-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
7NM1	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-126 分子名称: 14-3-3 protein sigma, 4-(4-pyrrolidin-1-ylpiperidin-1-yl)sulfonylbenzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-23 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NM9	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-110 分子名称: 14-3-3 protein sigma, 6-(2-bromanylimidazol-1-yl)pyridine-3-carbaldehyde, DI(HYDROXYETHYL)ETHER, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-23 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
8ILX	mCherry-LaM3 complex 分子名称: LAM3, MCherry fluorescent protein 著者 Liang, H, Liu, R, Ding, Y. 登録日 2023-03-05 公開日 2023-06-21 実験手法 X-RAY DIFFRACTION (3.29 Å) 主引用文献 Structural Insights into the Binding of Red Fluorescent Protein mCherry-Specific Nanobodies. Int J Mol Sci, 24, 2023
7S9Y	Helicobacter Hepaticus CcsBA Open Conformation 分子名称: Cytochrome c biogenesis protein, HEME B/C, PHOSPHATIDYLETHANOLAMINE 著者 Mendez, D.L, Lowder, E.P, Tillman, D.E, Sutherland, M.C, Collier, A.L, Rau, M.J, Fitzpatrick, J.A, Kranz, R.G. 登録日 2021-09-21 公開日 2021-12-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport. Nat.Chem.Biol., 18, 2022
3CKI	Crystal structure of the TACE-N-TIMP-3 complex 分子名称: ADAM 17, Metalloproteinase inhibitor 3, SODIUM ION, ... 著者 Wisniewska, M, Goettig, P, Maskos, K, Belouski, E, Winters, D, Hecht, R, Black, R, Bode, W. 登録日 2008-03-15 公開日 2008-08-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex. J.Mol.Biol., 381, 2008
7NK3	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-128 分子名称: 14-3-3 protein sigma, 2-(4-methylphenyl)sulfonyl-3,4-dihydro-1~{H}-isoquinoline, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-17 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
8IM1	mCherry-LaM1 complex 分子名称: LaM1, MCherry fluorescent protein, SULFATE ION 著者 Liang, H, Liu, R, Ding, Y. 登録日 2023-03-05 公開日 2023-06-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Insights into the Binding of Red Fluorescent Protein mCherry-Specific Nanobodies. Int J Mol Sci, 24, 2023
8C8U	Priestia megaterium mupirocin-resistant isoleucyl-tRNA synthetase 2 complexed with mupirocin 分子名称: Isoleucine--tRNA ligase, L(+)-TARTARIC ACID, MUPIROCIN, ... 著者 Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Gruic-Sovulj, I, Ban, N. 登録日 2023-01-21 公開日 2023-08-23 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14, 2023
7NLA	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-119 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-22 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
8C9G	Priestia megaterium mupirocin-sensitive isoleucyl-tRNA synthetase 1 complexed with mupirocin 分子名称: CHLORIDE ION, GLYCEROL, Isoleucine--tRNA ligase, ... 著者 Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I. 登録日 2023-01-22 公開日 2023-08-23 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14, 2023
8CEA	Cytochrome c maturation complex CcmABCD, E154Q 分子名称: Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ... 著者 Ilcu, L, Zhang, L, Einsle, O. 登録日 2023-02-01 公開日 2023-09-06 実験手法 ELECTRON MICROSCOPY (3.94 Å) 主引用文献 Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation. Nat Commun, 14, 2023
8CBQ	structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome 分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ... 著者 Koutna, E, Kouba, T, Novacek, J, Veverka, V. 登録日 2023-01-25 公開日 2023-09-06 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
7S86	Crystal structure of hydrophobin SC16, C2221 分子名称: 1,2-ETHANEDIOL, Hydrophobin, SODIUM ION 著者 Vergunst, K.L, Langelaan, D.N. 登録日 2021-09-17 公開日 2021-12-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The N-terminal tail of the hydrophobin SC16 is not required for rodlet formation Sci Rep, 12, 2022
5XSG	Ultrahigh resolution structure of FUS (37-42) SYSGYS determined by MicroED 分子名称: RNA-binding protein FUS 著者 Luo, F, Gui, X, Zhou, H, Li, D, Li, X, Liu, C. 登録日 2017-06-14 公開日 2018-04-04 最終更新日 2024-03-27 実験手法 ELECTRON CRYSTALLOGRAPHY (0.73 Å) 主引用文献 Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation. Nat. Struct. Mol. Biol., 25, 2018
8C8W	Priestia megaterium mupirocin hyper-resistant HIGH motif mutant of type 2 isoleucyl-tRNA synthetase complexed with an isoleucyl-adenylate analogue 分子名称: D(-)-TARTARIC ACID, Isoleucine--tRNA ligase, N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, ... 著者 Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I. 登録日 2023-01-21 公開日 2023-08-16 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14, 2023
7NJ9	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-133 分子名称: 14-3-3 protein sigma, 4-(3,4-dihydro-2~{H}-quinolin-1-ylsulfonyl)benzaldehyde, DI(HYDROXYETHYL)ETHER, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
8IF6	Conformational Dynamics of the D53-D3-D14 Complex in Strigolactone Signaling 分子名称: F-box/LRR-repeat MAX2 homolog, SKP1-like protein 20, Strigolactone esterase D14 著者 Liu, S.M, Wang, J. 登録日 2023-02-17 公開日 2023-07-12 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (7.09 Å) 主引用文献 Conformational Dynamics of the D53-D3-D14 Complex in Strigolactone Signaling. Plant Cell.Physiol., 64, 2023
7NJB	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-132 分子名称: 14-3-3 protein sigma, 4-piperidin-1-ylsulfonylbenzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
8CE1	Cytochrome c maturation complex CcmABCD 分子名称: Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ... 著者 Ilcu, L, Zhang, L, Einsle, O. 登録日 2023-02-01 公開日 2023-09-06 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation. Nat Commun, 14, 2023
4PN7	Crystal Structure of the TFIIH p34 N-terminal Domain 分子名称: Putative transcription factor 著者 Schmitt, D.R, Kuper, J, Elias, A, Kisker, C. 登録日 2014-05-23 公開日 2014-07-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.801 Å) 主引用文献 The Structure of the TFIIH p34 Subunit Reveals a Von Willebrand Factor A Like Fold. Plos One, 9, 2014
3LX1	Crystal Structure analysis of PCNA1 from Thermococcus kodakaraensis tk0535 分子名称: DNA polymerase sliding clamp 1, SULFATE ION 著者 Ladner, J.E, Kelman, Z, Pan, M. 登録日 2010-02-24 公開日 2011-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc.Natl.Acad.Sci.USA, 108, 2011
4PM5	Crystal structure of CTX-M-14 S70G beta-lactamase in complex with cefotaxime at 1.26 Angstroms resolution 分子名称: (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicy clo[4.2.0]oct-2-ene-2-carboxylic acid, Beta-lactamase CTX-M-14, SULFATE ION 著者 Adamski, C.J, Cardenas, A.M, Sankaran, B, Palzkill, T. 登録日 2014-05-20 公開日 2014-12-31 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.261 Å) 主引用文献 Molecular Basis for the Catalytic Specificity of the CTX-M Extended-Spectrum beta-Lactamases. Biochemistry, 54, 2015
7MY2	CryoEM structure of neutralizing nanobody Nb30 in complex with SARS-CoV2 spike 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb30, ... 著者 Xu, K, Kwong, P.D. 登録日 2021-05-20 公開日 2021-06-16 最終更新日 2021-07-28 実験手法 ELECTRON MICROSCOPY (2.65 Å) 主引用文献 Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants. Nature, 595, 2021
8C9D	Priestia megaterium W130Q mutant of type 2 isoleucyl-tRNA synthetase complexed with an isoleucyl-adenylate analogue 分子名称: D(-)-TARTARIC ACID, Isoleucine--tRNA ligase, N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, ... 著者 Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I. 登録日 2023-01-21 公開日 2023-08-16 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14, 2023

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