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6BCB
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BU of 6bcb by Molmil
A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog
分子名称: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ...
著者Sternweis, P.C, Chen, Z.
登録日2017-10-20
公開日2017-12-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
6CUP
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BU of 6cup by Molmil
Ras:SOS:Ras in complex with a small molecule activator
分子名称: FORMIC ACID, GLYCEROL, GTPase HRas, ...
著者Phan, J, Abbott, J, Fesik, S.W.
登録日2018-03-26
公開日2019-02-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.833 Å)
主引用文献Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS.
ACS Med Chem Lett, 9, 2018
5SZJ
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BU of 5szj by Molmil
Structure of human Rab10 in complex with the bMERB domain of Mical-cL
分子名称: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, MICAL C-terminal-like protein, ...
著者Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Mueller, M.P, Gazdag, E.M.
登録日2016-08-14
公開日2016-08-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
5TAR
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BU of 5tar by Molmil
Crystal structure of farnesylated and methylated kras4b in complex with PDE-delta (crystal form II - with ordered hypervariable region)
分子名称: 1,2-ETHANEDIOL, FARNESYL, GTPase KRas, ...
著者Dharmaiah, S, Tran, T.H, Simanshu, D.K.
登録日2016-09-10
公開日2016-11-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of recognition of farnesylated and methylated KRAS4b by PDE delta.
Proc.Natl.Acad.Sci.USA, 113, 2016
5SZI
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BU of 5szi by Molmil
Structure of human Rab8a in complex with the bMERB domain of Mical-cL
分子名称: MAGNESIUM ION, MICAL C-terminal-like protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Mueller, M.P, Gazdag, E.M.
登録日2016-08-14
公開日2016-08-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
5TB5
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BU of 5tb5 by Molmil
Crystal structure of full-length farnesylated and methylated KRAS4b in complex with PDE-delta (crystal form I - with partially disordered hypervariable region)
分子名称: 1,2-ETHANEDIOL, FARNESYL, GTPase KRas, ...
著者Dharmaiah, S, Tran, T.H, Simanshu, D.K.
登録日2016-09-11
公開日2016-11-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of recognition of farnesylated and methylated KRAS4b by PDE delta.
Proc.Natl.Acad.Sci.USA, 113, 2016
5UWU
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BU of 5uwu by Molmil
Crystal Structure of SMAD4 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: CHLORIDE ION, Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWQ
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BU of 5uwq by Molmil
Crystal Structure of CDC7 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Cell division cycle 7-related protein kinase, Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.278 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWJ
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BU of 5uwj by Molmil
Crystal Structure of FMRP NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.221 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWR
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BU of 5uwr by Molmil
Crystal Structure of CDC7 NES Peptide (extended) in complex with CRM1-Ran-RanBP1
分子名称: CHLORIDE ION, Cell division cycle 7-related protein kinase, Exportin-1, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5SZH
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BU of 5szh by Molmil
Structure of human Rab1b in complex with the bMERB domain of Mical-cL
分子名称: MAGNESIUM ION, MICAL C-terminal-like protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Goody, R.S, Mueller, M.P, Gazdag, E.M.
登録日2016-08-14
公開日2016-08-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
5SZK
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BU of 5szk by Molmil
Structure of human N-terminally engineered Rab1b in complex with the bMERB domain of Mical-cL
分子名称: MAGNESIUM ION, MICAL C-terminal-like protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Gazdag, E.M, Mueller, M.P.
登録日2016-08-14
公開日2016-08-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
5UWP
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BU of 5uwp by Molmil
Crystal Structure of mDia2 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.054 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWO
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BU of 5uwo by Molmil
Crystal Structure of Engineered FMRP-1b NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Engineered FMRP-1b peptide, Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.347 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWH
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BU of 5uwh by Molmil
Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWT
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BU of 5uwt by Molmil
Crystal Structure of Hxk2 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.342 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWS
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BU of 5uws by Molmil
Crystal Structure of X11L2 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Amyloid beta A4 precursor protein-binding family A member 3, Exportin-1,Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWW
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BU of 5uww by Molmil
Crystal Structure of DEAF1 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
分子名称: Deformed epidermal autoregulatory factor 1 homolog, Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.152 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWI
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BU of 5uwi by Molmil
Crystal Structure of HDAC5 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.143 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
2A9K
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BU of 2a9k by Molmil
Crystal structure of the C3bot-NAD-RalA complex reveals a novel type of action of a bacterial exoenzyme
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mono-ADP-ribosyltransferase C3, ...
著者Pautsch, A, Vogelsgesang, M, Trankle, J, Herrmann, C, Aktories, K.
登録日2005-07-12
公開日2005-10-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
Embo J., 24, 2005
2BCG
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BU of 2bcg by Molmil
Structure of doubly prenylated Ypt1:GDI complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GERAN-8-YL GERAN, GTP-binding protein YPT1, ...
著者Pylypenko, O, Rak, A, Alexandrov, K.
登録日2005-10-19
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling
Embo J., 25, 2006
1Z2C
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BU of 1z2c by Molmil
Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP
分子名称: Diaphanous protein homolog 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Rose, R, Weyand, M, Lammers, M, Ishizaki, T, Ahmadian, M.R, Wittinghofer, A.
登録日2005-03-08
公開日2005-05-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and mechanistic insights into the interaction between Rho and mammalian Dia.
Nature, 435, 2005
2A78
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BU of 2a78 by Molmil
Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mono-ADP-ribosyltransferase C3, ...
著者Pautsch, A, Vogelsgesang, M, Trankle, J, Herrmann, C, Aktories, K.
登録日2005-07-05
公開日2005-10-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
Embo J., 24, 2005
1Z0K
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BU of 1z0k by Molmil
Structure of GTP-Bound Rab4Q67L GTPase in complex with the central Rab binding domain of Rabenosyn-5
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FYVE-finger-containing Rab5 effector protein rabenosyn-5, GTP-binding protein, ...
著者Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G.
登録日2005-03-01
公開日2005-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
2BOV
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BU of 2bov by Molmil
Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MONO-ADP-RIBOSYLTRANSFERASE C3, ...
著者Holbourn, K.P, Sutton, J.M, Evans, H.R, Shone, C.C, Acharya, K.R.
登録日2005-04-14
公開日2005-04-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Molecular Recognition of an Adp-Ribosylating Clostridium Botulinum C3 Exoenzyme by Rala Gtpase
Proc.Natl.Acad.Sci.USA, 102, 2005

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