PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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3FHR	High resolution crystal structure of mitogen-activated protein kinase-activated protein kinase 3 (MK3)-inhibitor complex 分子名称: 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, MAP kinase-activated protein kinase 3 著者 Cheng, R.K.Y, Barker, J, Palan, S, Felicetti, B, Whittaker, M, Hesterkamp, T. 登録日 2008-12-10 公開日 2009-12-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 High-resolution crystal structure of human Mapkap kinase 3 in complex with a high affinity ligand Protein Sci., 19, 2010
1JFC	X-ray structure of nitric oxide reductase (cytochrome P450nor) in the ferrous CO state at atomic resolution 分子名称: CARBON MONOXIDE, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Shimizu, H, Adachi, S, Park, S.Y, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2001-06-20 公開日 2001-12-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 X-ray structure of nitric oxide reductase (cytochrome P450nor) at atomic resolution. Acta Crystallogr.,Sect.D, 58, 2002
1V0B	Crystal structure of the t198a mutant of pfpk5 分子名称: CELL DIVISION CONTROL PROTEIN 2 HOMOLOG 著者 Holton, S, Merckx, A, Burgess, D, Doerig, C, Noble, M, Endicott, J. 登録日 2004-03-26 公開日 2004-03-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of P. Falciparum Pfpk5 Test the Cdk Regulation Paradigm and Suggest Mechanisms of Small Molecule Inhibition Structure, 11, 2003
1JZN	crystal structure of a galactose-specific C-type lectin 分子名称: CALCIUM ION, CHLORIDE ION, Galactose-specific lectin, ... 著者 Walker, J.R, Nagar, B, Young, N.M, Hirama, T, Rini, J.M. 登録日 2001-09-16 公開日 2003-07-01 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 X-ray Crystal Structure of a Galactose-Specific C-Type Lectin Possessing a Novel Decameric Quaternary Structure. Biochemistry, 43, 2004
2DUV	Structure of CDK2 with a 3-hydroxychromones 分子名称: 2-(3,4-DIHYDROXYPHENYL)-8-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-3-HYDROXY-6-METHYL-4H-CHROMEN-4-ONE, Cell division protein kinase 2 著者 Kim, K.H, Lee, J, Park, T, Jeong, S, Hong, C. 登録日 2006-07-27 公開日 2007-01-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 3-Hydroxychromones as cyclin-dependent kinase inhibitors: synthesis and biological evaluation. Bioorg.Med.Chem.Lett., 17, 2007
3UYS	Crystal structure of apo human ck1d 分子名称: Casein kinase I isoform delta, SULFATE ION 著者 Huang, X. 登録日 2011-12-06 公開日 2012-01-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for the interaction between casein kinase 1 delta and a potent and selective inhibitor. J.Med.Chem., 55, 2012
1V4L	Crystal structure of a platelet agglutination factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus) 分子名称: mucrocetin alpha chain, mucrocetin beta chain 著者 Huang, K.-F, Ko, T.-P, Wang, A.H.-J. 登録日 2003-11-14 公開日 2003-12-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of a platelet-agglutinating factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus). Biochem.J., 378, 2004
3UO4	Aurora A in complex with RPM1680 分子名称: 1,2-ETHANEDIOL, 4-{[4-(biphenyl-2-ylamino)pyrimidin-2-yl]amino}benzoic acid, Aurora kinase A 著者 Martin, M.P, Zhu, J.-Y, Schonbrunn, E. 登録日 2011-11-16 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A. Acs Chem.Biol., 7, 2012
2ZB0	Crystal structure of P38 in complex with biphenyl amide inhibitor 分子名称: GLYCEROL, Mitogen-activated protein kinase 14, N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide 著者 Somers, D.O. 登録日 2007-10-13 公開日 2008-01-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode Bioorg.Med.Chem.Lett., 18, 2008
3UP7	Aurora A in complex with YL1-038-09 分子名称: 2-({2-[(4-carboxyphenyl)amino]pyrimidin-4-yl}amino)benzoic acid, Aurora kinase A 著者 Martin, M.P, Zhu, J.-Y, Schonbrunn, E. 登録日 2011-11-17 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Development of o-Chlorophenyl Substituted Pyrimidines as Exceptionally Potent Aurora Kinase Inhibitors. J.Med.Chem., 55, 2012
1JL6	Crystal Structure of CN-Ligated Component IV Glycera Dibranchiata Monomeric Hemoglobin 分子名称: CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, monomer hemoglobin component IV 著者 Park, H.J, Yang, C, Treff, N, Satterlee, J.D, Kang, C. 登録日 2001-07-16 公開日 2002-07-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal Structures of Unligated and CN-Ligated Glycera dibranchiata Monomer Ferric Hemoglobin Components III and IV Proteins, 49, 2002
3FLW	P38 kinase crystal structure in complex with pamapimod 分子名称: 6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxyethyl)propyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Ghate, M. 登録日 2008-12-19 公開日 2009-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Discovery of Pamapimod, R1503 and R1487 as Orally Bioavailable and Highly Selective Inhibitors of p38 Map Kinase To be Published
2DE8	Crystal structure of porcine pancreatic elastase with a unique conformation induced by Tris 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Elastase-1 著者 Kinoshita, T, Tada, T. 登録日 2006-02-09 公開日 2006-07-11 最終更新日 2020-09-09 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Tris(hydroxymethyl)aminomethane induces conformational change and crystal-packing contraction of porcine pancreatic elastase. Acta Crystallogr.,Sect.F, 62, 2006
1JLU	Crystal Structure of the Catalytic Subunit of cAMP-dependent Protein Kinase Complexed with a Phosphorylated Substrate Peptide and Detergent 分子名称: AMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR, ... 著者 Madhusudan, Trafny, E.A, Xuong, N.-H, Adams, J.A, Ten Eyck, L.F, Taylor, S.S, Sowadski, J.M. 登録日 2001-07-16 公開日 2001-08-01 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer. Protein Sci., 3, 1994
1VAU	Xenon derivative of hen egg-white lysozyme 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION, ... 著者 Takeda, K, Miyatake, H, Park, S.Y, Kawamoto, M, Kamiya, N, Miki, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-02-19 公開日 2005-03-08 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Multi-wavelength anomalous diffraction method for I and Xe atoms using ultra-high-energy X-rays from SPring-8 J.Appl.Crystallogr., 37, 2004
3FMJ	P38 kinase crystal structure in complex with 4-(5-Methyl-3-phenyl-isoxazol-4-yl)-pyrimidin-2-ylamine 分子名称: 4-(5-methyl-3-phenylisoxazol-4-yl)pyrimidin-2-amine, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Ghate, M. 登録日 2008-12-22 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Discovery of Pamapimod and R1487 as Orally Bioavailable and Highly Selective Inhibitors of p38 Map Kinase To be Published
1VBZ	Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Ba2+ solution 分子名称: BARIUM ION, Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A 著者 Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A. 登録日 2004-03-03 公開日 2004-05-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A Conformational Switch controls hepatitis delta virus ribozyme catalysis NATURE, 429, 2004
2ZJW	Crystal structure of human CK2 alpha complexed with Ellagic acid 分子名称: 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione, Casein kinase II subunit alpha 著者 Sekiguchi, Y, Kinoshita, T, Nakaniwa, T, Tada, T. 登録日 2008-03-11 公開日 2009-03-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural insight into human CK2alpha in complex with the potent inhibitor ellagic acid Bioorg.Med.Chem.Lett., 19, 2009
2DGP	Solution structure of the N-terminal RNA binding domain in Bruno-like 4 RNA-binding protein 分子名称: Bruno-like 4, RNA binding protein 著者 Abe, C, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-03-15 公開日 2006-09-15 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the N-terminal RNA binding domain in Bruno-like 4 RNA-binding protein To be Published
1UIE	ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 分子名称: LYSOZYME 著者 Motoshima, H, Ohmura, T, Ueda, T, Imoto, T. 登録日 1996-11-26 公開日 1997-11-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Analysis of the stability of mutant lysozymes at position 15 using X-ray crystallography. J.Biochem.(Tokyo), 122, 1997
2DJ2	The solution structure of the second thioredoxin domain of mouse Protein disulfide-isomerase A4 分子名称: Protein disulfide-isomerase A4 著者 Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-03-30 公開日 2006-09-30 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The solution structure of the second thioredoxin domain of mouse Protein disulfide-isomerase A4 To be Published
1JPB	Sperm Whale met-Myoglobin (low temperature; high pressure) 分子名称: PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, myoglobin 著者 Urayama, P, Gruner, S.M, Phillips Jr, G.N. 登録日 2001-08-01 公開日 2002-01-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Probing substates in sperm whale myoglobin using high-pressure crystallography. Structure, 10, 2002
2DHB	THREE DIMENSIONAL FOURIER SYNTHESIS OF HORSE DEOXYHAEMOGLOBIN AT 2.8 ANGSTROMS RESOLUTION 分子名称: HEMOGLOBIN (DEOXY) (ALPHA CHAIN), HEMOGLOBIN (DEOXY) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE 著者 Perutz, M.F. 登録日 1973-11-01 公開日 1977-06-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Three dimensional fourier synthesis of horse deoxyhaemoglobin at 2.8 Angstrom units resolution. Nature, 228, 1970
1UIC	ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 分子名称: LYSOZYME 著者 Motoshima, H, Ohmura, T, Ueda, T, Imoto, T. 登録日 1996-11-26 公開日 1997-11-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Analysis of the stability of mutant lysozymes at position 15 using X-ray crystallography. J.Biochem.(Tokyo), 122, 1997
1URE	NMR STRUCTURE OF INTESTINAL FATTY ACID-BINDING PROTEIN COMPLEXED WITH PALMITATE, 20 STRUCTURES 分子名称: INTESTINAL FATTY ACID-BINDING PROTEIN, PALMITIC ACID 著者 Hodsdon, M.E, Ponder, J.W, Cistola, D.P. 登録日 1996-06-17 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The NMR solution structure of intestinal fatty acid-binding protein complexed with palmitate: application of a novel distance geometry algorithm. J.Mol.Biol., 264, 1996

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