PDB: 97310 件ウェブページステータス検索Chemie searchBIRD

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6NML	Ternary structure of the T130K mutant of ANT-4'' with Neomycin and AMPCPP 分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, Kanamycin nucleotidyltransferase, MAGNESIUM ION, ... 著者 Cuneo, M.J, Selvaraj, B. 登録日 2019-01-11 公開日 2020-01-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 'Catch and Release": a Variation of the Archetypal Nucleotidyl Transfer Reaction Acs Catalysis, 2020
1SKS	Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template 分子名称: 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', DNA polymerase, ... 著者 Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. 登録日 2004-03-05 公開日 2004-07-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Nat.Struct.Mol.Biol., 11, 2004
1SL1	Binary 5' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template 分子名称: 5'-D(*CP*CP*C*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*TP*(2DA))-3', DNA polymerase, ... 著者 Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. 登録日 2004-03-05 公開日 2004-07-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Nat.Struct.Mol.Biol., 11, 2004
5EWG	Ternary complex of human DNA polymerase eta inserting rATP opposite an 8-Oxodeoxyguanosine Lesion 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Su, Y, Egli, M, Guengerich, F.P. 登録日 2015-11-20 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
5EWF	Ternary complex of human DNA polymerase eta inserting rCTP opposite an 8-Oxodeoxyguanosine Lesion 分子名称: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Su, Y, Egli, M, Guengerich, F.P. 登録日 2015-11-20 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.782 Å) 主引用文献 Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
5EWE	Ternary complex of human DNA polymerase eta inserting rCTP opposite template G 分子名称: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Su, Y, Egli, M, Guengerich, F.P. 登録日 2015-11-20 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
7CO8	Ternary complex of DNA polymerase Mu with 2-nt gapped DNA (T:dGMPNPP) 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... 著者 Guo, M, Zhao, Y. 登録日 2020-08-04 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.697 Å) 主引用文献 Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
7COC	Ternary complex of DNA polymerase Mu (K438A/Q441A) with 1-nt gapped DNA (T:dGMPNPP) 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... 著者 Guo, M, Zhao, Y. 登録日 2020-08-04 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
7COB	Ternary complex of DNA polymerase Mu (Q441A) with 1-nt gapped DNA (T:dGMPNPP) 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... 著者 Guo, M, Zhao, Y. 登録日 2020-08-04 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.797 Å) 主引用文献 Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
7CO6	Binary complex of DNA polymerase Mu with 1-nt gapped DNA (templating thymine) 分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... 著者 Guo, M, Zhao, Y. 登録日 2020-08-04 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
7CO9	Ternary complex of DNA polymerase Mu with 1-nt gapped DNA (T:dGMPNPP) and Mg 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... 著者 Guo, M, Zhao, Y. 登録日 2020-08-04 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.599 Å) 主引用文献 Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
7COA	Ternary complex of DNA polymerase Mu with 1-nt gapped DNA (T:dGMPNPP) and Mn 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... 著者 Guo, M, Zhao, Y. 登録日 2020-08-04 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
1SKW	Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template 分子名称: 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', DNA polymerase, ... 著者 Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. 登録日 2004-03-05 公開日 2004-07-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Nat.Struct.Mol.Biol., 11, 2004
2W5Y	Binary Complex of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine. 分子名称: HISTONE-LYSINE N-METHYLTRANSFERASE HRX, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Southall, S.M, Wong, P.S, Odho, Z, Roe, S.M, WIlson, J.R. 登録日 2008-12-15 公開日 2009-02-10 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for the Requirement of Additional Factors for Mll1 Set Domain Activity and Recognition of Epigenetic Marks. Mol.Cell, 33, 2009
5EDW	Ternary structure of Dpo4 bound to G in the template base paired with incoming dTTP 分子名称: CALCIUM ION, DNA (5'-D(*CP*TP*AP*AP*CP*GP*GP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2015-10-22 公開日 2016-11-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structure of Dpo4 DNA polymerase replicating across the genotoxic N7-methylguanine lesion To Be Published
4X7H	Co-crystal Structure of PERK bound to N-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3-dihydro-1H-pyrazole-4-carboxamide inhibitor 分子名称: Eukaryotic translation initiation factor 2-alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3, N-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3-dihydro-1H-pyrazole-4-carboxamide, SULFATE ION 著者 Shaffer, P.L, Bellon, S.F, Long, A.M, Chen, H. 登録日 2014-12-09 公開日 2015-02-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of 1H-Pyrazol-3(2H)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK). J.Med.Chem., 58, 2015
5HCC	Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Dermacentor andersoni RaCI3. 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Jore, M.M, Johnson, S, Lea, S.M. 登録日 2016-01-04 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Structural basis for therapeutic inhibition of complement C5. Nat.Struct.Mol.Biol., 23, 2016
5HCD	Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus microplus RaCI2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Complement C5, ... 著者 Jore, M.M, Johnson, S, Lea, S.M. 登録日 2016-01-04 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Structural basis for therapeutic inhibition of complement C5. Nat.Struct.Mol.Biol., 23, 2016
5HCE	Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus appendiculatus RaCI1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Complement C5, ... 著者 Jore, M.M, Johnson, S, Lea, S.M. 登録日 2016-01-04 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Structural basis for therapeutic inhibition of complement C5. Nat.Struct.Mol.Biol., 23, 2016
7OL3	Human ATL1 N417ins (catalytic core) 分子名称: Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Kelly, C.M, Sondermann, H. 登録日 2021-05-19 公開日 2021-07-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A novel insertion mutation in atlastin 1 is associated with spastic quadriplegia, increased membrane tethering, and aberrant conformational switching. J.Biol.Chem., 298, 2021
6V92	RSC-NCP 分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC14, ... 著者 Patel, A.B, Moore, C.M, Greber, B.J, Nogales, E. 登録日 2019-12-13 公開日 2020-01-15 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement. Elife, 8, 2019
7SUK	Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from R2TP-depleted Yeast Cells 分子名称: 18S pre-rRNA, 40S ribosomal protein S11-A, 40S ribosomal protein S13, ... 著者 Rai, J, Zhao, Y, Li, H. 登録日 2021-11-17 公開日 2022-07-06 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.99 Å) 主引用文献 Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome. Commun Biol, 5, 2022
1Q2R	Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate 分子名称: 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase, RNA (5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(N)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3'), ... 著者 Xie, W, Liu, X, Huang, R.H. 登録日 2003-07-25 公開日 2003-09-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate Nat.Struct.Biol., 10, 2003
1Q2S	Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate 分子名称: 5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(PQ1)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3', 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase, ... 著者 Xie, W, Liu, X, Huang, R.H. 登録日 2003-07-25 公開日 2003-09-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate Nat.Struct.Biol., 10, 2003
7N4D	Translation initiation factor eif-5a family protein from Naegleria fowleri ATCC 30863 分子名称: Eukaryotic translation initiation factor 5A 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-06-03 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Translation initiation factor eif-5a family protein from Naegleria fowleri ATCC 30863 to be published

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