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2GCF
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Solution structure of the N-terminal domain of the coppper(I) ATPase PacS in its apo form
分子名称: Cation-transporting ATPase pacS
著者Banci, L, Bertini, I, Ciofi-Baffoni, S, Kandias, N.G, Spyroulias, G.A, Robinson, N.J, Structural Proteomics in Europe (SPINE)
登録日2006-03-14
公開日2006-05-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The delivery of copper for thylakoid import observed by NMR.
Proc.Natl.Acad.Sci.Usa, 103, 2006
5IH5
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BU of 5ih5 by Molmil
Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A
分子名称: 6-(3-chlorophenyl)pteridine-2,4,7-triamine, Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, ...
著者Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H.
登録日2016-02-29
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1.
Cell Chem Biol, 23, 2016
2GD7
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BU of 2gd7 by Molmil
The Structure of the Cyclin T-binding domain of Hexim1 reveals the molecular basis for regulation of transcription elongation
分子名称: HEXIM1 protein
著者Dames, S.A.
登録日2006-03-15
公開日2007-06-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb.
Proc.Natl.Acad.Sci.Usa, 104, 2007
7RWE
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BU of 7rwe by Molmil
Crystal structure of CDK2 liganded with compound GPHR787
分子名称: 5-nitro-2-[(3-phenylpropyl)amino]benzoic acid, Cyclin-dependent kinase 2
著者Sun, L, Schonbrunn, E.
登録日2021-08-19
公開日2022-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice.
J.Med.Chem., 66, 2023
5IHC
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BU of 5ihc by Molmil
MELK in complex with NVS-MELK12B
分子名称: 4-[1-(2-fluorophenyl)-1H-pyrazol-4-yl]-3-[(piperidin-4-yl)methoxy]pyridine, Maternal embryonic leucine zipper kinase
著者Sprague, E.R, Brazell, T.
登録日2016-02-29
公開日2016-06-01
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight.
J.Med.Chem., 59, 2016
2ROK
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BU of 2rok by Molmil
Solution structure of the cap-binding domain of PARN complexed with the cap analog
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, poly(A)-specific ribonuclease
著者Nagata, T, Suzuki, S, Endo, R, Shirouzu, M, Terada, T, Inoue, M, Kigawa, T, Guntert, P, Hayashizaki, Y, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-03-28
公開日2009-02-10
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognition.
Nucleic Acids Res., 36, 2008
5IBN
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BU of 5ibn by Molmil
Ultra high resolution crystal structure of the apo- form of second bromodomain of BRD2.
分子名称: Bromodomain-containing protein 2, CHLORIDE ION, GLYCEROL, ...
著者Tripathi, S.K, Padmanabhan, B.
登録日2016-02-22
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (0.94 Å)
主引用文献A Novel Phenanthridionone Based Scaffold As a Potential Inhibitor of the BRD2 Bromodomain: Crystal Structure of the Complex
Plos One, 11, 2016
2RP3
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BU of 2rp3 by Molmil
Solution Structure of Cyanovirin-N Domain B Mutant
分子名称: Cyanovirin-N
著者Matei, E, Furey, W, Gronenborn, A.M.
登録日2008-04-30
公開日2008-08-19
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping
Structure, 16, 2008
7RVI
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BU of 7rvi by Molmil
Segment from naked mole rat (elk T174S) prion protein 168-176 QYNNQNSFV
分子名称: CACODYLATE ION, Major prion protein, SODIUM ION
著者Glynn, C, Rodriguez, J.A, Hernandez, E.
登録日2021-08-18
公開日2022-08-24
最終更新日2024-05-22
実験手法ELECTRON CRYSTALLOGRAPHY (1.05 Å)
主引用文献Structural and Biophysical Consequences of Sequence Variation in the B2a2 Loop of Mammalian Prions
To be published
2GGZ
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BU of 2ggz by Molmil
Crystal Structure of Human Guanylate Cyclase Activating Protein-3
分子名称: CALCIUM ION, Guanylyl cyclase-activating protein 3
著者Stephen, R.
登録日2006-03-24
公開日2006-05-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Crystal Structure of GCAP3 Suggests Molecular Mechanism of GCAP-linked Cone Dystrophies.
J.Mol.Biol., 359, 2006
7RV8
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BU of 7rv8 by Molmil
Crystal structure of the BCL6 BTB domain in complex with OICR-10268
分子名称: DIMETHYL SULFOXIDE, Isoform 2 of B-cell lymphoma 6 protein, N-[5-chloro-2-(morpholin-4-yl)pyridin-4-yl]-2-{5-(3-cyano-4-hydroxy-5-methylphenyl)-3-[3-(1-methyl-1H-pyrazol-4-yl)prop-2-yn-1-yl]-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl}acetamide
著者Kuntz, D.A, Prive, G.G.
登録日2021-08-18
公開日2022-08-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structure of the BCL6 BTB domain
To Be Published
2RPN
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BU of 2rpn by Molmil
A crucial role for high intrinsic specificity in the function of yeast SH3 domains
分子名称: Actin-binding protein, Actin-regulating kinase 1
著者Stollar, E.J, Garcia, B, Chong, A, Forman-Kay, J, Davidson, A.
登録日2008-06-12
公開日2009-06-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p
J.Biol.Chem., 284, 2009
2GHT
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BU of 2ght by Molmil
CTD-specific phosphatase Scp1 in complex with peptide from C-terminal domain of RNA polymerase II
分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
著者Zhang, Y, Noel, J.P.
登録日2006-03-27
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
2RO8
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BU of 2ro8 by Molmil
Solution structure of calcium bound soybean calmodulin isoform 1 N-terminal domain
分子名称: CALCIUM ION, Calmodulin
著者Ishida, H, Huang, H, Yamniuk, A.P, Takaya, Y, Vogel, H.J.
登録日2008-03-14
公開日2008-04-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structures of two soybean calmodulin isoforms provide a structural basis for their selective target activation properties
J.Biol.Chem., 283, 2008
2GIB
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BU of 2gib by Molmil
Crystal structure of the SARS coronavirus nucleocapsid protein dimerization domain
分子名称: Nucleocapsid protein, SULFATE ION
著者Yu, I.M, Oldham, M.L, Zhang, J, Chen, J.
登録日2006-03-28
公開日2006-04-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein dimerization domain reveals evolutionary linkage between corona- and arteriviridae.
J.Biol.Chem., 281, 2006
7RVL
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BU of 7rvl by Molmil
Segment from the Y169F mutant of the human prion protein 168-176 EFSNQNNFV
分子名称: Major prion protein
著者Glynn, C, Rodriguez, J.A, Hernandez, E.
登録日2021-08-18
公開日2022-08-24
最終更新日2024-05-22
実験手法ELECTRON CRYSTALLOGRAPHY (1 Å)
主引用文献Structural and Biophysical Consequences of Sequence Variation in the B2a2 Loop of Mammalian Prions
To be published
5ICH
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BU of 5ich by Molmil
Crystal structure of Enterococcus faecalis lipoate-protein ligase A (lplA-2) in complex with 8BO-AMP
分子名称: 5'-O-[(S)-[(8-bromooctanoyl)oxy](hydroxy)phosphoryl]adenosine, Lipoate--protein ligase
著者Hughes, S.J, Song, J.H, Antoshchenko, T, Park, H.W.
登録日2016-02-23
公開日2017-03-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of Enterococcus faecalis lipoate-protein ligase A (lplA-2) in complex with 8BO-AMP
to be published
2RQ4
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BU of 2rq4 by Molmil
Refinement of RNA binding domain 3 in CUG triplet repeat RNA-binding protein 1
分子名称: CUG-BP- and ETR-3-like factor 1
著者Tsuda, K, Kuwasako, K, Takahashi, M, Someya, T, Inoue, M, Terada, T, Kobayashi, N, Shirouzu, M, Kigawa, T, Guntert, P, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2009-01-19
公開日2009-08-04
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural basis for the sequence-specific RNA-recognition mechanism of human CUG-BP1 RRM3
Nucleic Acids Res., 2009
2FVX
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BU of 2fvx by Molmil
CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: G57T REDUCED (277K)
分子名称: FLAVIN MONONUCLEOTIDE, FLAVODOXIN
著者Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R.
登録日1996-12-19
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes.
Biochemistry, 36, 1997
2ROL
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BU of 2rol by Molmil
Structural Basis of PxxDY motif recognition in SH3 binding
分子名称: 12-meric peptide from T-cell surface glycoprotein CD3 epsilon chain, Epidermal growth factor receptor kinase substrate 8-like protein 1
著者Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Paakkonen, K, Saksela, K, Permi, P.
登録日2008-04-02
公開日2009-03-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis of PxxDY motif recognition in SH3 binding
J.Mol.Biol., 382, 2008
5IJ6
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BU of 5ij6 by Molmil
Crystal structure of Enterococcus faecalis lipoate-protein ligase A (lplA-1) in complex with lipoic acid
分子名称: CHLORIDE ION, LIPOIC ACID, Lipoate--protein ligase, ...
著者Hughes, S.J, Lyle, A.G, Song, J.H, Antoshchenko, T, Park, H.
登録日2016-03-01
公開日2017-03-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Enterococcus faecalis lipoate-protein ligase A (lplA-1) in complex with lipoic acid
to be published
2FMR
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BU of 2fmr by Molmil
KH1 FROM THE FRAGILE X PROTEIN FMR1, NMR, 18 STRUCTURES
分子名称: FMR1 PROTEIN
著者Musco, G, Kharrat, A, Stier, G, Fraternali, F, Gibson, T.J, Nilges, M, Pastore, A.
登録日1997-10-06
公開日1998-04-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome.
Nat.Struct.Biol., 4, 1997
2RQQ
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BU of 2rqq by Molmil
Structure of C-terminal region of Cdt1
分子名称: DNA replication factor Cdt1
著者Jee, J.G, Mizuno, T, Kamada, K, Tochio, H, Hiroaki, H, Hanaoka, F, Shirakawa, M.
登録日2009-10-14
公開日2010-03-23
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure and mutagenesis studies of the C-terminal region of licensing factor Cdt1 enable the identification of key residues for binding to replicative helicase Mcm proteins
J.Biol.Chem., 285, 2010
5IJG
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BU of 5ijg by Molmil
Crystal structure of O-acetylhomoserine sulfhydrolase from Brucella melitensis at 2.0 A resolution
分子名称: Cys/Met metabolism pyridoxal-phosphate-dependent enzyme, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE
著者Boyko, K.M, Nikolaeva, A.Y, Koolikova, V.V, Kotlov, M.I, Demidkina, T.V, Popov, V.O.
登録日2016-03-02
公開日2017-04-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of O-acetylhomoserine sulfhydrolase from Brucella melitensis at 2.0 A resolution
To Be Published
2FOW
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BU of 2fow by Molmil
THE RNA BINDING DOMAIN OF RIBOSOMAL PROTEIN L11: THREE-DIMENSIONAL STRUCTURE OF THE RNA-BOUND FORM OF THE PROTEIN, NMR, 26 STRUCTURES
分子名称: RIBOSOMAL PROTEIN L11
著者Hinck, A.P, Markus, M.A, Huang, S, Grzesiek, S, Kustanovich, I, Draper, D.E, Torchia, D.A.
登録日1997-05-26
公開日1997-11-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The RNA binding domain of ribosomal protein L11: three-dimensional structure of the RNA-bound form of the protein and its interaction with 23 S rRNA.
J.Mol.Biol., 274, 1997

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