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3M35
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Trypsin in complex with the inhibitor 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423)
分子名称: 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide, CALCIUM ION, Cationic trypsin
著者Alexander, R.S.
登録日2010-03-08
公開日2010-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-N-[3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-1H-pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor
J.Med.Chem., 46, 2003
3DEE
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BU of 3dee by Molmil
CRYSTAL STRUCTURE OF A PUTATIVE REGULATORY PROTEIN INVOLVED IN TRANSCRIPTION (NGO1945) FROM NEISSERIA GONORRHOEAE FA 1090 AT 2.25 A RESOLUTION
分子名称: CHLORIDE ION, IMIDAZOLE, Putative regulatory protein
著者Joint Center for Structural Genomics (JCSG)
登録日2008-06-09
公開日2008-08-05
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation.
Acta Crystallogr.,Sect.F, 66, 2010
3M8L
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BU of 3m8l by Molmil
Crystal Structure Analysis of the Feline Calicivirus Capsid Protein
分子名称: Capsid protein
著者Zhou, Y, Prasad, B.V.V.
登録日2010-03-18
公開日2010-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Conformational changes in the capsid of a calicivirus upon interaction with its functional receptor
J.Virol., 84, 2010
2ZG2
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BU of 2zg2 by Molmil
Crystal Structure of Two N-terminal Domains of Native Siglec-5
分子名称: Sialic acid-binding Ig-like lectin 5
著者Zhuravleva, M.A, Sun, P.D.
登録日2008-01-17
公開日2008-02-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural implications of Siglec-5-mediated sialoglycan recognition
J.Mol.Biol., 375, 2008
3J98
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BU of 3j98 by Molmil
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa)
分子名称: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
著者Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
登録日2014-12-05
公開日2015-01-28
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (8.4 Å)
主引用文献Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
2ZSR
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BU of 2zsr by Molmil
Carbonmonoxy Sperm Whale Myoglobin at 120 K: Laser on [450 min]
分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S.
登録日2008-09-17
公開日2009-02-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin
Proc.Natl.Acad.Sci.USA, 106, 2009
2ZT0
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BU of 2zt0 by Molmil
Carbonmonoxy Sperm Whale Myoglobin at 100 K: Laser on [750 min]
分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S.
登録日2008-09-18
公開日2009-02-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin
Proc.Natl.Acad.Sci.USA, 106, 2009
2ZWB
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Neutron crystal structure of wild type human lysozyme in D2O
分子名称: Lysozyme C
著者Chiba-Kamoshida, K, Matsui, T, Chatake, T, Ohhara, T, Ostermann, A, Tanaka, I, Yutani, K, Niimura, N.
登録日2008-12-02
公開日2009-12-08
最終更新日2023-11-01
実験手法NEUTRON DIFFRACTION (1.8 Å)
主引用文献Site-specific softening of peptide bonds by localized deuterium observed by neutron crystallography of human lysozyme
To be Published
3JC5
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BU of 3jc5 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
分子名称: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
著者Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
登録日2015-11-24
公開日2016-02-10
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
2ZSY
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BU of 2zsy by Molmil
Carbonmonoxy Sperm Whale Myoglobin at 140 K: Laser on [750 min]
分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S.
登録日2008-09-18
公開日2009-02-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin.
Proc.Natl.Acad.Sci.USA, 106, 2009
2ZUT
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BU of 2zut by Molmil
Crystal structure of Galacto-N-biose/Lacto-N-biose I phosphorylase in complex with GalNAc
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, GLYCEROL, Lacto-N-biose phosphorylase, ...
著者Hidaka, M, Nishimoto, M, Kitaoka, M, Wakagi, T, Shoun, H, Fushinobu, S.
登録日2008-10-28
公開日2008-12-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of galacto-N-biose/lacto-N-biose I phosphorylase: A large deformation of a tim barrel scaffold
J.Biol.Chem., 284, 2009
3JA8
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BU of 3ja8 by Molmil
Cryo-EM structure of the MCM2-7 double hexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ...
著者Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N.
登録日2015-05-09
公開日2015-08-05
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the eukaryotic MCM complex at 3.8 angstrom
Nature, 524, 2015
3JCJ
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Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T.
登録日2015-12-18
公開日2016-03-09
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
7XS0
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BU of 7xs0 by Molmil
Trimer structure of HtrA from Helicobacter pylori bound with a tripeptide
分子名称: Periplasmic serine endoprotease DegP-like, UNK-UNK-UNK
著者Cui, L, Liu, W.
登録日2022-05-12
公開日2023-05-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal structures and solution conformations of HtrA from Helicobacter pylori reveal pH-dependent oligomeric conversion and conformational rearrangements.
Int.J.Biol.Macromol., 243, 2023
3C90
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BU of 3c90 by Molmil
The 1.25 A Resolution Structure of Phosphoribosyl-ATP Pyrophosphohydrolase from Mycobacterium tuberculosis, crystal form II
分子名称: Phosphoribosyl-ATP pyrophosphatase
著者Javid-Majd, F, Yang, D, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2008-02-14
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 64, 2008
7XS2
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BU of 7xs2 by Molmil
Monomer structure of HtrA from Helicobacter pylori
分子名称: Periplasmic serine endoprotease DegP-like
著者Cui, L, Liu, W.
登録日2022-05-12
公開日2023-05-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structures and solution conformations of HtrA from Helicobacter pylori reveal pH-dependent oligomeric conversion and conformational rearrangements.
Int.J.Biol.Macromol., 243, 2023
3BT1
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BU of 3bt1 by Molmil
Structure of urokinase receptor, urokinase and vitronectin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, ...
著者Huang, M.
登録日2007-12-27
公開日2008-03-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
3J7Y
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BU of 3j7y by Molmil
Structure of the large ribosomal subunit from human mitochondria
分子名称: 16S rRNA, ADENOSINE MONOPHOSPHATE, CRIF1, ...
著者Brown, A, Amunts, A, Bai, X.C, Sugimoto, Y, Edwards, P.C, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V.
登録日2014-08-26
公開日2014-10-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of the large ribosomal subunit from human mitochondria.
Science, 346, 2014
7XYK
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BU of 7xyk by Molmil
Structure of WSSV thymidylate synthase in complex with dUMP and raltitrexed
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, SULFATE ION, TOMUDEX, ...
著者Ma, Q, Liu, C, Zang, K.
登録日2022-06-01
公開日2023-06-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.433 Å)
主引用文献Structure of WSSV thymidylate synthase in complex with dUMP and raltitrexed
To Be Published
7XYJ
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BU of 7xyj by Molmil
Structure of WSSV thymidylate synthase in complex with dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PENTAETHYLENE GLYCOL, ...
著者Ma, Q, Liu, C, Zang, K.
登録日2022-06-01
公開日2023-06-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.275 Å)
主引用文献Structure of WSSV thymidylate synthase in complex with dUMP
To Be Published
3BON
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BU of 3bon by Molmil
Structure of the C. botulinum neurotoxin serotype A with Zn2+ cofactor bound
分子名称: Neurotoxin A, ZINC ION
著者Silvaggi, N.R, Allen, K.N.
登録日2007-12-17
公開日2008-05-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Catalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex.
Biochemistry, 47, 2008
3BT2
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BU of 3bt2 by Molmil
Structure of urokinase receptor, urokinase and vitronectin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, ...
著者Huang, M.
登録日2007-12-27
公開日2008-03-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
3CW1
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Crystal Structure of Human Spliceosomal U1 snRNP
分子名称: Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, ...
著者Pomeranz Krummel, D.A, Oubridge, C, Leung, A.K, Li, J, Nagai, K.
登録日2008-04-21
公開日2009-03-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (5.493 Å)
主引用文献Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution.
Nature, 458, 2009
3J97
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BU of 3j97 by Molmil
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State II)
分子名称: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
著者Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
登録日2014-12-05
公開日2015-01-28
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3JCN
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BU of 3jcn by Molmil
Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association: Initiation Complex I
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T.
登録日2016-01-04
公開日2016-03-09
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016

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