2DX0
 
 | | Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2 | | 分子名称: | Phospholipase C, gamma 2, SULFATE ION | | 著者 | Handa, N, Takagi, T, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-08-22 | | 公開日 | 2007-09-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2
To be Published
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3HMO
 | | Crystal structure of human Mps1 catalytic domain in complex with the inhibitor staurosporine | | 分子名称: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Dual specificity protein kinase TTK, GLYCEROL, ... | | 著者 | Chu, M.L.H, Chavas, L.M.G, Williams, D.H, Tabernero, L, Eyers, P.A. | | 登録日 | 2009-05-29 | | 公開日 | 2010-02-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes.
Biochemistry, 49, 2010
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2DQI
 | | Crystal structure of hyhel-10 FV mutant (Ly50a) complexed with hen egg lysozyme | | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | | 著者 | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | | 登録日 | 2006-05-26 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
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1UOS
 | | The Crystal Structure of the Snake Venom Toxin Convulxin | | 分子名称: | CONVULXIN ALPHA, CONVULXIN BETA | | 著者 | Batuwangala, T, Leduc, M, Gibbins, J.M, Bon, C, Jones, E.Y. | | 登録日 | 2003-09-22 | | 公開日 | 2003-10-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of the Snake-Venom Toxin Convulxin
Acta Crystallogr.,Sect.D, 60, 2004
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2VNY
 | | Structure of PKA-PKB chimera complexed with (1-(9H-Purin-6-yl) piperidin-4-yl)amine | | 分子名称: | 1-(9H-purin-6-yl)piperidin-4-amine, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, CAMP-DEPENDENT PROTEIN KINASE, ... | | 著者 | Caldwell, J.J, Davies, T.G, Donald, A, McHardy, T, Rowlands, M.G, Aherne, G.W, Hunter, L.K, Taylor, K, Ruddle, R, Raynaud, F.I, Verdonk, M, Workman, P, Garrett, M.D, Collins, I. | | 登録日 | 2008-02-08 | | 公開日 | 2008-04-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Identification of 4-(4-Aminopiperidin-1-Yl)-7H-Pyrrolo[2,3-D]Pyrimidines as Selective Inhibitors of Protein Kinase B Through Fragment Elaboration.
J.Med.Chem., 51, 2008
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2XKD
 | | Structure of Nek2 bound to aminopyrazine compound 12 | | 分子名称: | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]benzoic acid, CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2 | | 著者 | Mas-Droux, C, Bayliss, R. | | 登録日 | 2010-07-07 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: Sar and Structural Characterization.
J.Med.Chem., 53, 2010
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2XM8
 | | Co-crystal structure of a small molecule inhibitor bound to the kinase domain of Chk2 | | 分子名称: | 2-{4-[(3S)-PYRROLIDIN-3-YLAMINO]QUINAZOLIN-2-YL}PHENOL, SERINE/THREONINE-PROTEIN KINASE CHK2 | | 著者 | Caldwell, J.J, Welsh, E.J, Matijssen, C, Anderson, V.E, Antoni, L, Boxall, K, Urban, F, Hayes, A, Raynaud, F.I, Rigoreau, L.J, Raynham, T, Aherne, G.W, Pearl, L.H, Oliver, A.W, Garrett, M.D, Collins, I. | | 登録日 | 2010-07-26 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2.
J.Med.Chem., 54, 2011
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3VBQ
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1SFI
 | | High resolution structure of a potent, cyclic protease inhibitor from sunflower seeds | | 分子名称: | CALCIUM ION, SULFATE ION, TRYPSIN, ... | | 著者 | Luckett, S, Garcia, R.S, Barker, J.J, Konarev, A.V, Shewry, P, Clarke, A.R, Brady, R.L. | | 登録日 | 1998-12-16 | | 公開日 | 1999-07-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds.
J.Mol.Biol., 290, 1999
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1JJJ
 | | SOLUTION STRUCTURE OF RECOMBINANT HUMAN EPIDERMAL-TYPE FATTY ACID BINDING PROTEIN | | 分子名称: | EPIDERMAL-TYPE FATTY ACID BINDING PROTEIN (E-FABP) | | 著者 | Gutierrez-Gonzalez, L.H, Ludwig, C, Hohoff, C, Rademacher, M, Hanhoff, T, Rueterjans, H, Spener, F, Luecke, C. | | 登録日 | 2001-07-06 | | 公開日 | 2002-06-19 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and backbone dynamics of human epidermal-type fatty
acid-binding protein (E-FABP)
BIOCHEM.J., 364, 2002
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2XMY
 | | Discovery and Characterisation of 2-Anilino-4-(thiazol-5-yl) pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents | | 分子名称: | 4-[4-(3,4-DIMETHYL-2-OXO-2,3-DIHYDRO-THIAZOL-5-YL)-PYRIMIDIN-2-YLAMINO]-N-(2-METHOXY-ETHYL)-BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 | | 著者 | Wang, S, Griffiths, G, Midgley, C.A, Barnett, A.L, Cooper, M, Grabarek, J, Ingram, L, Jackson, W, Kontopidis, G, McClue, S.J, McInnes, C, McLachlan, J, Meades, C, Mezna, M, Stuart, I, Thomas, M.P, Zheleva, D.I, Lane, D.P, Jackson, R.C, Glover, D.M, Blake, D.G, Fischer, P.M. | | 登録日 | 2010-07-29 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents
Chem.Biol., 17, 2010
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2DHG
 | | Solution structure of the C-terminal RNA recognition motif in tRNA selenocysteine associated protein | | 分子名称: | tRNA selenocysteine associated protein (SECP43) | | 著者 | Imai, T, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-03-23 | | 公開日 | 2006-09-23 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the C-terminal RNA recognition motif in tRNA selenocysteine associated protein
To be Published
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3HRC
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1UVZ
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2DJU
 | | Solution structures of the fn3 domain of human receptor-type tyrosine-protein phosphatase F | | 分子名称: | Receptor-type tyrosine-protein phosphatase F | | 著者 | Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-05 | | 公開日 | 2006-10-05 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the fn3 domain of human receptor-type tyrosine-protein phosphatase F
to be published
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2DLK
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2DM0
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1JZK
 | | Crystal Structure of Scapharca inaequivalvis HbI, I114F mutant (deoxy) | | 分子名称: | GLOBIN I - ARK SHELL, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Knapp, J.E, Gibson, Q.H, Cushing, L, Royer Jr, W.E. | | 登録日 | 2001-09-16 | | 公開日 | 2001-12-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Restricting the Ligand-Linked Heme Movement in Scapharca Dimeric Hemoglobin Reveals Tight Coupling between Distal and Proximal
Contributions to Cooperativity.
Biochemistry, 40, 2001
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2DML
 | | The solution structure of the first thioredoxin domain of mouse Protein disulfide-isomerase A6 | | 分子名称: | Protein disulfide-isomerase A6 | | 著者 | Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-22 | | 公開日 | 2006-10-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the first thioredoxin domain of mouse Protein disulfide-isomerase A6
To be Published
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1UZ2
 | | The Cys121Ser Mutant of Beta-Lactoglobulin | | 分子名称: | BETA-LACTOGLOBULIN | | 著者 | McNae, I, Jayat, D, Haertle, T, Holt, C, Sawyer, L. | | 登録日 | 2004-03-03 | | 公開日 | 2004-05-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A recombinant C121S mutant of bovine beta-lactoglobulin is more susceptible to peptic digestion and to denaturation by reducing agents and heating.
Biochemistry, 43, 2004
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2Y0A
 | | Structure of DAPK1 construct residues 1-304 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DEATH-ASSOCIATED PROTEIN KINASE 1 | | 著者 | Yumerefendi, H, Mas, P.J, Dordevic, N, McCarthy, A.A, Hart, D.J. | | 登録日 | 2010-12-01 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Library-Based Construct Screening of Death-Associated Protein Kinase 1 Identifies the Minimal Calmodulin Interaction Region and Autoinhibitory Conformation of the Catalytic Domain
To be Published
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1UYU
 | | Xenon COMPLEX OF wildtype P450CAM FROM PSEUDOMONAS PUTIDA | | 分子名称: | CAMPHOR, CYTOCHROME P450-CAM, POTASSIUM ION, ... | | 著者 | Wade, R.C, Winn, P.J, Schlichting, I, Sudarko, X. | | 登録日 | 2004-03-02 | | 公開日 | 2005-03-07 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Survey of Active Site Access Channels in Cytochromes P450
J.Inorg.Biochem., 98, 2004
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2DQG
 | | Crystal structure of hyhel-10 FV mutant (Hy53f) complexed with hen egg lysozyme | | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | | 著者 | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | | 登録日 | 2006-05-25 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
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2DGW
 | | Solution structure of the second RNA recognition motif in RNA-binding protein 19 | | 分子名称: | Probable RNA-binding protein 19 | | 著者 | Abe, C, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-03-16 | | 公開日 | 2006-09-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the second RNA recognition motif in RNA-binding protein 19
To be Published
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1UTJ
 | | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | | 分子名称: | BENZYLAMINE, CALCIUM ION, TRYPSIN I | | 著者 | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | | 登録日 | 2003-12-09 | | 公開日 | 2004-01-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements
Protein Sci., 13, 2004
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