PDB: 2524 件ウェブページステータス検索Chemie searchBIRD

---

5FLX	Mammalian 40S HCV-IRES complex 分子名称: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... 著者 Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T. 登録日 2015-10-28 公開日 2015-12-23 最終更新日 2017-08-30 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA. Embo J., 34, 2015
5HE0	Bovine GRK2 in complex with Gbetagamma subunits and CCG215022 分子名称: (4S)-4-{4-fluoro-3-[(pyridin-2-ylmethyl)carbamoyl]phenyl}-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Cato, M.C, Waninger-Saroni, J, Tesmer, J.J.G. 登録日 2016-01-05 公開日 2016-05-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors. J.Med.Chem., 59, 2016
5HE3	Bovine GRK2 in complex with Gbetagamma subunits and CCG224411 分子名称: (4~{S})-4-[3-[2-(2,6-dimethylphenyl)ethylcarbamoyl]-4-fluoranyl-phenyl]-~{N}-(1~{H}-indazol-5-yl)-6-methyl-2-oxidanylidene-3,4-dihydro-1~{H}-pyrimidine-5-carboxamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Cato, M.C, Tesmer, J.J.G. 登録日 2016-01-05 公開日 2016-05-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors. J.Med.Chem., 59, 2016
5HE2	Bovine GRK2 in complex with Gbetagamma subunits and CCG224406 分子名称: (4~{S})-4-[3-[(2,6-dimethoxyphenyl)methylcarbamoyl]-4-fluoranyl-phenyl]-~{N}-(1~{H}-indazol-5-yl)-6-methyl-2-oxidanylidene-3,4-dihydro-1~{H}-pyrimidine-5-carboxamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Cato, M.C, Waninger-Saroni, J, Tesmer, J.J.G. 登録日 2016-01-05 公開日 2016-05-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors. J.Med.Chem., 59, 2016
5HE1	Human GRK2 in complex with Gbetagamma subunits and CCG224062 分子名称: (4~{S})-4-[4-fluoranyl-3-(isoquinolin-1-ylmethylcarbamoyl)phenyl]-~{N}-(1~{H}-indazol-5-yl)-6-methyl-2-oxidanylidene-3,4-dihydro-1~{H}-pyrimidine-5-carboxamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Cato, M.C, Tesmer, J.J.G. 登録日 2016-01-05 公開日 2016-05-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors. J.Med.Chem., 59, 2016
5GAN	The overall structure of the yeast spliceosomal U4/U6.U5 tri-snRNP at 3.7 Angstrom 分子名称: 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, Pre-mRNA-processing factor 31, ... 著者 Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. 登録日 2015-12-15 公開日 2016-01-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution. Nature, 530, 2016
5GAP	Body region of the U4/U6.U5 tri-snRNP 分子名称: 13 kDa ribonucleoprotein-associated protein, Pre-mRNA-processing factor 31, Pre-mRNA-splicing factor 6, ... 著者 Nguyen, T.H.D, Galej, W.P, Oubridge, C, Bai, X.C, Newman, A, Scheres, S, Nagai, K. 登録日 2015-12-15 公開日 2016-01-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution. Nature, 530, 2016
7PZY	Structure of the vacant Candida albicans 80S ribosome 分子名称: 1,4-DIAMINOBUTANE, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Zgadzay, Y, Kolosova, O, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. 登録日 2021-10-13 公開日 2022-05-18 最終更新日 2022-06-08 実験手法 ELECTRON MICROSCOPY (2.32 Å) 主引用文献 E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
7Q0F	Structure of Candida albicans 80S ribosome in complex with phyllanthoside 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... 著者 Zgadzay, Y, Kolosova, O, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. 登録日 2021-10-14 公開日 2022-05-18 最終更新日 2022-06-08 実験手法 ELECTRON MICROSCOPY (2.64 Å) 主引用文献 E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
7Q0P	Structure of the Candida albicans 80S ribosome in complex with anisomycin 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... 著者 Kolosova, O, Zgadzay, Y, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. 登録日 2021-10-15 公開日 2022-05-18 最終更新日 2022-06-08 実験手法 ELECTRON MICROSCOPY (2.77 Å) 主引用文献 E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
7Q08	Structure of Candida albicans 80S ribosome in complex with cycloheximide 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Zgadzay, Y, Kolosova, O, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. 登録日 2021-10-14 公開日 2022-05-25 最終更新日 2022-06-08 実験手法 ELECTRON MICROSCOPY (2.56 Å) 主引用文献 E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
7Q0R	Structure of the Candida albicans 80S ribosome in complex with blasticidin s 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... 著者 Kolosova, O, Zgadzay, Y, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. 登録日 2021-10-16 公開日 2022-05-25 最終更新日 2022-06-08 実験手法 ELECTRON MICROSCOPY (2.67 Å) 主引用文献 E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
7QDZ	80S-bound human SKI complex in the closed state 分子名称: Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... 著者 Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. 登録日 2021-12-01 公開日 2022-02-09 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
7QDR	Apo human SKI complex in the closed state 分子名称: Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 著者 Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. 登録日 2021-11-29 公開日 2022-02-02 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
7QDS	Apo human SKI complex in the open state 分子名称: Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 著者 Koegel, A, Keidel, A, Bonneau, A, Schaefer, I.B, Conti, E. 登録日 2021-11-30 公開日 2022-02-02 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
7QDY	RNA-bound human SKI complex 分子名称: Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... 著者 Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. 登録日 2021-12-01 公開日 2022-02-09 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
7QEP	Cryo-EM structure of the ribosome from Encephalitozoon cuniculi 分子名称: 18S ribosomal RNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... 著者 Nicholson, D, Ranson, N.A, Melnikov, S.V. 登録日 2021-12-03 公開日 2022-02-09 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Adaptation to genome decay in the structure of the smallest eukaryotic ribosome Nat Commun, 13, 2022
7QP6	Structure of the human 48S initiation complex in open state (h48S AUG open) 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. 登録日 2022-01-03 公開日 2022-05-11 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7QP7	Structure of the human 48S initiation complex in closed state (h48S AUG closed) 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. 登録日 2022-01-03 公開日 2022-05-11 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7QIY	Specific features and methylation sites of a plant ribosome. 40S head ribosomal subunit. 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA head, 40S head ribosomal protein eS19, ... 著者 Cottilli, P, Itoh, Y, Amunts, A. 登録日 2021-12-16 公開日 2022-06-15 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Cryo-EM structure and rRNA modification sites of a plant ribosome. Plant Commun., 3, 2022
7QGG	Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Pulk, A, Kipper, K, Mansour, A. 登録日 2021-12-08 公開日 2022-10-26 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state. J.Mol.Biol., 434, 2022
7QVP	Human collided disome (di-ribosome) stalled on XBP1 mRNA 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Denk, T.G, Tesina, P, Beckmann, R. 登録日 2022-01-22 公開日 2022-10-12 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation. Nat Commun, 13, 2022
7QIZ	Specific features and methylation sites of a plant 80S ribosome 分子名称: 1,4-DIAMINOBUTANE, 18S, 25S rRNA, ... 著者 Cottilli, P, Itoh, Y, Amunts, A. 登録日 2021-12-16 公開日 2022-08-03 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.38 Å) 主引用文献 Cryo-EM structure and rRNA modification sites of a plant ribosome. Plant Commun., 3, 2022
7QVM	Human Oxytocin receptor (OTR) oxytocin Gq chimera (mGoqi) complex 分子名称: Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Waltenspuhl, Y, Ehrenmann, J, Vacca, S, Thom, C, Medalia, O, Pluckthun, A. 登録日 2022-01-21 公開日 2022-08-10 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 Structural basis for the activation and ligand recognition of the human oxytocin receptor. Nat Commun, 13, 2022
7QCA	Spraguea lophii ribosome 分子名称: 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S10, ... 著者 Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B. 登録日 2021-11-22 公開日 2022-11-30 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (2.79 Å) 主引用文献 CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state Nat Microbiol, 2023

<40414243444546474849505152535455>