7XXI
| Cryo-EM structure of the purinergic receptor P2Y12R in complex with 2MeSADP and Gi | 分子名称: | 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Tan, Q, Li, B, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-05-30 | 公開日 | 2023-06-07 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R. Protein Cell, 14, 2023
|
|
7VFX
| The structure of Formyl Peptide Receptor 1 in complex with Gi and peptide agonist fMIFL | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, X.K, Chen, G, Liao, Q.W, Du, Y, Hu, H.L, Ye, D.Q. | 登録日 | 2021-09-14 | 公開日 | 2022-09-21 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns. Nat Commun, 13, 2022
|
|
8WJX
| |
8X2K
| OEA bound GPR3-Gs complex structure | 分子名称: | (Z)-N-(2-hydroxyethyl)octadec-9-enamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Geng, C, Yang, D, Jun, X. | 登録日 | 2023-11-09 | 公開日 | 2024-04-03 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Structural and functional characterization of the endogenous agonist for orphan receptor GPR3. Cell Res., 34, 2024
|
|
8H4I
| DHA-bound FFAR4 in complex with Gs | 分子名称: | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | He, Y, Yin, H. | 登録日 | 2022-10-10 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
|
|
8H4L
| DHA-bound FFAR4 in complex with Gq | 分子名称: | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | He, Y, Yin, H. | 登録日 | 2022-10-10 | 公開日 | 2023-06-21 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
|
|
8H4K
| GW9508-bound FFAR4 in complex with Gq | 分子名称: | 3-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)propanoic acid, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | He, Y, Yin, H. | 登録日 | 2022-10-10 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
|
|
7WVU
| Cryo-EM structure of the human formyl peptide receptor 1 in complex with fMLF and Gi1 | 分子名称: | FME-LEU-PHE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-02-11 | 公開日 | 2022-04-13 | 最終更新日 | 2024-10-30 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13, 2022
|
|
8IYS
| TUG891-bound FFAR4 in complex with Gq | 分子名称: | 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | He, Y, Yin, H. | 登録日 | 2023-04-06 | 公開日 | 2023-06-21 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
|
|
2BC8
| [Sec2,3,8,12]-ImI | 分子名称: | Alpha-conotoxin ImI | 著者 | Armishaw, C.J. | 登録日 | 2005-10-18 | 公開日 | 2006-03-14 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | {alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists. J.Biol.Chem., 281, 2006
|
|
2BC7
| Solution structure of [Sec2,8]-ImI | 分子名称: | Alpha-conotoxin ImI | 著者 | Armishaw, C.J. | 登録日 | 2005-10-18 | 公開日 | 2006-03-14 | 最終更新日 | 2024-10-30 | 実験手法 | SOLUTION NMR | 主引用文献 | {alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists. J.Biol.Chem., 281, 2006
|
|
2H8S
| Solution structure of alpha-conotoxin Vc1.1 | 分子名称: | Alpha-conotoxin Vc1A | 著者 | Clark, R.J, Fischer, H, Nevin, S.T, Adams, D.J, Craik, D.J. | 登録日 | 2006-06-07 | 公開日 | 2006-06-27 | 最終更新日 | 2024-10-09 | 実験手法 | SOLUTION NMR | 主引用文献 | The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1. J.Biol.Chem., 281, 2006
|
|
2BYS
| CRYSTAL STRUCTURE OF ACHBP FROM APLYSIA CALIFORNICA IN complex with lobeline | 分子名称: | ACETYLCHOLINE-BINDING PROTEIN, LOBELINE | 著者 | Hansen, S.B, Sulzenbacher, G, Huxford, T, Marchot, P, Taylor, P, Bourne, Y. | 登録日 | 2005-08-04 | 公開日 | 2005-10-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations. Embo J., 24, 2005
|
|
1TXB
| SOLUTION NMR STRUCTURE OF TOXIN B, A LONG NEUROTOXIN FROM THE VENOM OF THE KING COBRA, 10 STRUCTURES | 分子名称: | TOXIN B | 著者 | Peng, S.-S, Kumar, T.K.S, Jayaraman, G, Chang, C.-C, Yu, C. | 登録日 | 1996-07-20 | 公開日 | 1997-10-15 | 最終更新日 | 2024-10-30 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of toxin b, a long neurotoxin from the venom of the king cobra (Ophiophagus hannah). J.Biol.Chem., 272, 1997
|
|
1TXA
| SOLUTION NMR STRUCTURE OF TOXIN B, A LONG NEUROTOXIN FROM THE VENOM OF THE KING COBRA, MINIMIZED AVERAGE STRUCTURE | 分子名称: | TOXIN B | 著者 | Peng, S.-S, Kumar, T.K.S, Jayaraman, G, Chang, C.-C, Yu, C. | 登録日 | 1996-07-20 | 公開日 | 1997-10-15 | 最終更新日 | 2024-11-06 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of toxin b, a long neurotoxin from the venom of the king cobra (Ophiophagus hannah). J.Biol.Chem., 272, 1997
|
|
1KBA
| |
3EBX
| REFINEMENT AT 1.4 ANGSTROMS RESOLUTION OF A MODEL OF ERABUTOXIN B. TREATMENT OF ORDERED SOLVENT AND DISCRETE DISORDER | 分子名称: | ERABUTOXIN B, SULFATE ION | 著者 | Smith, J.L, Corfield, P.W.R, Hendrickson, W.A, Low, B.W. | 登録日 | 1988-01-15 | 公開日 | 1988-04-16 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Refinement at 1.4 A resolution of a model of erabutoxin b: treatment of ordered solvent and discrete disorder. Acta Crystallogr.,Sect.A, 44, 1988
|
|
3RQU
| Crystal structure of a prokaryotic pentameric ligand-gated ion channel, ELIC | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ELIC Pentameric Ligand Gated Ion Channel from Erwinia Chrysanthemi, GLYCEROL | 著者 | Pan, J.J, Chen, Q, Yoshida, K, Cohen, A, Kong, X.P, Xu, Y, Tang, P. | 登録日 | 2011-04-28 | 公開日 | 2012-03-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.089 Å) | 主引用文献 | Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine. Nat Commun, 3, 2012
|
|
6LI3
| cryo-EM structure of GPR52-miniGs-NB35 | 分子名称: | G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Li, M, Wang, N, Xu, F, Wu, J, Lei, M. | 登録日 | 2019-12-10 | 公開日 | 2020-02-26 | 最終更新日 | 2020-03-18 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Structural basis of ligand recognition and self-activation of orphan GPR52. Nature, 579, 2020
|
|
1HAJ
| A beta-Hairpin Structure in a 13-mer Peptide that Binds a-Bungarotoxin with High Affinity and Neutralizes its Toxicity | 分子名称: | ALPHA-BUNGAROTOXIN, PEPTIDE | 著者 | Scherf, T, Kasher, R, Balass, M, Fridkin, M, Fuchs, S, Katchalski-Katzir, E. | 登録日 | 2001-04-05 | 公開日 | 2001-05-25 | 最終更新日 | 2024-10-23 | 実験手法 | SOLUTION NMR | 主引用文献 | A Beta-Hairpin Structure in a 13-mer Peptide that Binds Alpha-Bungarotoxin with High Affinity and Neutralizes its Toxicity Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
1HAA
| A beta-Hairpin Structure in a 13-mer Peptide that Binds a-Bungarotoxin with High Affinity and Neutralizes its Toxicity | 分子名称: | ALPHA-BUNGAROTOXIN, PEPTIDE | 著者 | Scherf, T, Kasher, R, Balass, M, Fridkin, M, Fuchs, S, Katchalski-Katzir, E. | 登録日 | 2001-04-05 | 公開日 | 2001-05-25 | 最終更新日 | 2024-10-23 | 実験手法 | SOLUTION NMR | 主引用文献 | A Beta-Hairpin Structure in a 13-mer Peptide that Binds Alpha-Bungarotoxin with High Affinity and Neutralizes its Toxicity Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
4LFT
| Structure of alpha-elapitoxin-Dpp2d isolated from Black Mamba (Dendroaspis polylepis) venom | 分子名称: | Alpha-elapitoxin-Dpp2a | 著者 | Wang, C.I.A, Reeks, T, Lewis, R.J, Alewood, P.F, Durek, T. | 登録日 | 2013-06-27 | 公開日 | 2014-06-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Isolation and Structural and Pharmacological Characterization of alpha-Elapitoxin-Dpp2d, an Amidated Three Finger Toxin from Black Mamba Venom. Biochemistry, 53, 2014
|
|
4ALX
| Crystal Structure of Ls-AChBP complexed with the potent nAChR antagonist DHbE | 分子名称: | (4bS,6S)-6-methoxy-1,4,6,7,9,10,12,13-octahydro-3H,5H-pyrano[4',3':3,4]pyrido[2,1-i]indol-3-one, ACETYLCHOLINE BINDING PROTEIN, MAGNESIUM ION, ... | 著者 | Shahsavar, A, Kastrup, J.S, Nielsen, E.O, Kristensen, J.L, Gajhede, M, Balle, T. | 登録日 | 2012-03-06 | 公開日 | 2012-08-29 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of Lymnaea Stagnalis Achbp Complexed with the Potent Nachr Antagonist Dh-Betab-E Suggests a Unique Mode of Antagonism Plos One, 7, 2012
|
|
5CO5
| |
3ERA
| RECOMBINANT ERABUTOXIN A (S8T MUTANT) | 分子名称: | ERABUTOXIN A, THIOCYANATE ION | 著者 | Gaucher, J.F, Menez, R, Arnoux, B, Menez, A, Ducruix, A. | 登録日 | 1997-06-25 | 公開日 | 1997-12-31 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | High resolution x-ray analysis of two mutants of a curaremimetic snake toxin Eur.J.Biochem., 267, 2000
|
|