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7XXI
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Cryo-EM structure of the purinergic receptor P2Y12R in complex with 2MeSADP and Gi
分子名称: 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Tan, Q, Li, B, Han, S, Zhao, Q, Wu, B.
登録日2022-05-30
公開日2023-06-07
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R.
Protein Cell, 14, 2023
7VFX
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The structure of Formyl Peptide Receptor 1 in complex with Gi and peptide agonist fMIFL
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wang, X.K, Chen, G, Liao, Q.W, Du, Y, Hu, H.L, Ye, D.Q.
登録日2021-09-14
公開日2022-09-21
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns.
Nat Commun, 13, 2022
8WJX
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ADP-bound purinergic receptor 1 in complex with miniGs/q
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHOLESTEROL, GNAS complex locus, ...
著者Gu, Q.C, Tang, W.Q.
登録日2023-09-26
公開日2024-10-02
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献ADP-bound purinergic receptor 1 in complex with miniGs/q
To Be Published
8X2K
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BU of 8x2k by Molmil
OEA bound GPR3-Gs complex structure
分子名称: (Z)-N-(2-hydroxyethyl)octadec-9-enamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Geng, C, Yang, D, Jun, X.
登録日2023-11-09
公開日2024-04-03
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural and functional characterization of the endogenous agonist for orphan receptor GPR3.
Cell Res., 34, 2024
8H4I
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DHA-bound FFAR4 in complex with Gs
分子名称: DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者He, Y, Yin, H.
登録日2022-10-10
公開日2023-06-21
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity.
Cell Res., 33, 2023
8H4L
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DHA-bound FFAR4 in complex with Gq
分子名称: DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者He, Y, Yin, H.
登録日2022-10-10
公開日2023-06-21
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity.
Cell Res., 33, 2023
8H4K
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GW9508-bound FFAR4 in complex with Gq
分子名称: 3-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)propanoic acid, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者He, Y, Yin, H.
登録日2022-10-10
公開日2023-06-21
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity.
Cell Res., 33, 2023
7WVU
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Cryo-EM structure of the human formyl peptide receptor 1 in complex with fMLF and Gi1
分子名称: FME-LEU-PHE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B.
登録日2022-02-11
公開日2022-04-13
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin.
Nat Commun, 13, 2022
8IYS
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BU of 8iys by Molmil
TUG891-bound FFAR4 in complex with Gq
分子名称: 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, GUANOSINE-5'-DIPHOSPHATE, ...
著者He, Y, Yin, H.
登録日2023-04-06
公開日2023-06-21
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity.
Cell Res., 33, 2023
2BC8
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[Sec2,3,8,12]-ImI
分子名称: Alpha-conotoxin ImI
著者Armishaw, C.J.
登録日2005-10-18
公開日2006-03-14
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献{alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists.
J.Biol.Chem., 281, 2006
2BC7
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Solution structure of [Sec2,8]-ImI
分子名称: Alpha-conotoxin ImI
著者Armishaw, C.J.
登録日2005-10-18
公開日2006-03-14
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献{alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists.
J.Biol.Chem., 281, 2006
2H8S
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Solution structure of alpha-conotoxin Vc1.1
分子名称: Alpha-conotoxin Vc1A
著者Clark, R.J, Fischer, H, Nevin, S.T, Adams, D.J, Craik, D.J.
登録日2006-06-07
公開日2006-06-27
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1.
J.Biol.Chem., 281, 2006
2BYS
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BU of 2bys by Molmil
CRYSTAL STRUCTURE OF ACHBP FROM APLYSIA CALIFORNICA IN complex with lobeline
分子名称: ACETYLCHOLINE-BINDING PROTEIN, LOBELINE
著者Hansen, S.B, Sulzenbacher, G, Huxford, T, Marchot, P, Taylor, P, Bourne, Y.
登録日2005-08-04
公開日2005-10-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
Embo J., 24, 2005
1TXB
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BU of 1txb by Molmil
SOLUTION NMR STRUCTURE OF TOXIN B, A LONG NEUROTOXIN FROM THE VENOM OF THE KING COBRA, 10 STRUCTURES
分子名称: TOXIN B
著者Peng, S.-S, Kumar, T.K.S, Jayaraman, G, Chang, C.-C, Yu, C.
登録日1996-07-20
公開日1997-10-15
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Solution structure of toxin b, a long neurotoxin from the venom of the king cobra (Ophiophagus hannah).
J.Biol.Chem., 272, 1997
1TXA
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BU of 1txa by Molmil
SOLUTION NMR STRUCTURE OF TOXIN B, A LONG NEUROTOXIN FROM THE VENOM OF THE KING COBRA, MINIMIZED AVERAGE STRUCTURE
分子名称: TOXIN B
著者Peng, S.-S, Kumar, T.K.S, Jayaraman, G, Chang, C.-C, Yu, C.
登録日1996-07-20
公開日1997-10-15
最終更新日2024-11-06
実験手法SOLUTION NMR
主引用文献Solution structure of toxin b, a long neurotoxin from the venom of the king cobra (Ophiophagus hannah).
J.Biol.Chem., 272, 1997
1KBA
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BU of 1kba by Molmil
CRYSTAL STRUCTURE OF KAPPA-BUNGAROTOXIN AT 2.3-ANGSTROM RESOLUTION
分子名称: KAPPA-BUNGAROTOXIN
著者Dewan, J.C, Grant, G.A, Sacchettini, J.C.
登録日1994-07-13
公開日1994-12-20
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of kappa-bungarotoxin at 2.3-A resolution.
Biochemistry, 33, 1994
3EBX
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BU of 3ebx by Molmil
REFINEMENT AT 1.4 ANGSTROMS RESOLUTION OF A MODEL OF ERABUTOXIN B. TREATMENT OF ORDERED SOLVENT AND DISCRETE DISORDER
分子名称: ERABUTOXIN B, SULFATE ION
著者Smith, J.L, Corfield, P.W.R, Hendrickson, W.A, Low, B.W.
登録日1988-01-15
公開日1988-04-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Refinement at 1.4 A resolution of a model of erabutoxin b: treatment of ordered solvent and discrete disorder.
Acta Crystallogr.,Sect.A, 44, 1988
3RQU
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BU of 3rqu by Molmil
Crystal structure of a prokaryotic pentameric ligand-gated ion channel, ELIC
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ELIC Pentameric Ligand Gated Ion Channel from Erwinia Chrysanthemi, GLYCEROL
著者Pan, J.J, Chen, Q, Yoshida, K, Cohen, A, Kong, X.P, Xu, Y, Tang, P.
登録日2011-04-28
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.089 Å)
主引用文献Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine.
Nat Commun, 3, 2012
6LI3
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cryo-EM structure of GPR52-miniGs-NB35
分子名称: G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Li, M, Wang, N, Xu, F, Wu, J, Lei, M.
登録日2019-12-10
公開日2020-02-26
最終更新日2020-03-18
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Structural basis of ligand recognition and self-activation of orphan GPR52.
Nature, 579, 2020
1HAJ
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A beta-Hairpin Structure in a 13-mer Peptide that Binds a-Bungarotoxin with High Affinity and Neutralizes its Toxicity
分子名称: ALPHA-BUNGAROTOXIN, PEPTIDE
著者Scherf, T, Kasher, R, Balass, M, Fridkin, M, Fuchs, S, Katchalski-Katzir, E.
登録日2001-04-05
公開日2001-05-25
最終更新日2024-10-23
実験手法SOLUTION NMR
主引用文献A Beta-Hairpin Structure in a 13-mer Peptide that Binds Alpha-Bungarotoxin with High Affinity and Neutralizes its Toxicity
Proc.Natl.Acad.Sci.USA, 98, 2001
1HAA
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A beta-Hairpin Structure in a 13-mer Peptide that Binds a-Bungarotoxin with High Affinity and Neutralizes its Toxicity
分子名称: ALPHA-BUNGAROTOXIN, PEPTIDE
著者Scherf, T, Kasher, R, Balass, M, Fridkin, M, Fuchs, S, Katchalski-Katzir, E.
登録日2001-04-05
公開日2001-05-25
最終更新日2024-10-23
実験手法SOLUTION NMR
主引用文献A Beta-Hairpin Structure in a 13-mer Peptide that Binds Alpha-Bungarotoxin with High Affinity and Neutralizes its Toxicity
Proc.Natl.Acad.Sci.USA, 98, 2001
4LFT
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BU of 4lft by Molmil
Structure of alpha-elapitoxin-Dpp2d isolated from Black Mamba (Dendroaspis polylepis) venom
分子名称: Alpha-elapitoxin-Dpp2a
著者Wang, C.I.A, Reeks, T, Lewis, R.J, Alewood, P.F, Durek, T.
登録日2013-06-27
公開日2014-06-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Isolation and Structural and Pharmacological Characterization of alpha-Elapitoxin-Dpp2d, an Amidated Three Finger Toxin from Black Mamba Venom.
Biochemistry, 53, 2014
4ALX
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Crystal Structure of Ls-AChBP complexed with the potent nAChR antagonist DHbE
分子名称: (4bS,6S)-6-methoxy-1,4,6,7,9,10,12,13-octahydro-3H,5H-pyrano[4',3':3,4]pyrido[2,1-i]indol-3-one, ACETYLCHOLINE BINDING PROTEIN, MAGNESIUM ION, ...
著者Shahsavar, A, Kastrup, J.S, Nielsen, E.O, Kristensen, J.L, Gajhede, M, Balle, T.
登録日2012-03-06
公開日2012-08-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Lymnaea Stagnalis Achbp Complexed with the Potent Nachr Antagonist Dh-Betab-E Suggests a Unique Mode of Antagonism
Plos One, 7, 2012
5CO5
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Crystal structure of Ac-AChBP in complex with conotoxin GIC
分子名称: Alpha-conotoxin GIC, Soluble acetylcholine receptor
著者Wang, X.Q, Xu, M.Y, Luo, S.L, Lin, B.
登録日2015-07-19
公開日2016-07-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Ac-AChBP in complex with conotoxin GIC
To Be Published
3ERA
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RECOMBINANT ERABUTOXIN A (S8T MUTANT)
分子名称: ERABUTOXIN A, THIOCYANATE ION
著者Gaucher, J.F, Menez, R, Arnoux, B, Menez, A, Ducruix, A.
登録日1997-06-25
公開日1997-12-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献High resolution x-ray analysis of two mutants of a curaremimetic snake toxin
Eur.J.Biochem., 267, 2000

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件を2024-11-06に公開中

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