PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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6D0Q	Structure of a DNA retention-prone PCNA variant 分子名称: Proliferating cell nuclear antigen 著者 Kelch, B.A, Gaubitz, C. 登録日 2018-04-10 公開日 2019-05-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.80051017 Å) 主引用文献 Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex. Nucleic Acids Res., 47, 2019
4FTG	The crystal structure of an AHNAK peptide in complex with the S100A10/AnxA2 heterotetramer 分子名称: Annexin A2, ISOPROPYL ALCOHOL, Neuroblast differentiation-associated protein AHNAK, ... 著者 Ozorowski, G, Luecke, H. 登録日 2012-06-27 公開日 2013-01-02 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.5054 Å) 主引用文献 Structure of a C-terminal AHNAK peptide in a 1:2:2 complex with S100A10 and an acetylated N-terminal peptide of annexin A2. Acta Crystallogr.,Sect.D, 69, 2013
6D0R	Structure of a DNA retention-prone PCNA variant 分子名称: Proliferating cell nuclear antigen 著者 Kelch, B.A, Gaubitz, C. 登録日 2018-04-10 公開日 2019-05-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.85856962 Å) 主引用文献 Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex. Nucleic Acids Res., 47, 2019
6CZQ	A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model 分子名称: CALCIUM ION, Calmodulin-1, SULFATE ION, ... 著者 Nam, Y.W, Zhang, M. 登録日 2018-04-09 公開日 2018-08-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A V-to-F substitution in SK2 channels causes Ca2+hypersensitivity and improves locomotion in a C. elegans ALS model. Sci Rep, 8, 2018
6CIX	Lactam cyclised mimetic of a fragment of p21 分子名称: p21 著者 Wegener, K.L. 登録日 2018-02-25 公開日 2018-07-04 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp. Chemistry, 24, 2018
6D6R	Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction 分子名称: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ... 著者 Weick, E.-M, Lima, C.D. 登録日 2018-04-22 公開日 2018-06-20 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex. Cell, 173, 2018
1O9G	rRNA methyltransferase aviRa from Streptomyces viridochromogenes at 1.5A 分子名称: RRNA METHYLTRANSFERASE 著者 Mosbacher, T.G, Schulz, G.E. 登録日 2002-12-13 公開日 2003-05-16 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of the Avilamycin Resistance-Conferring Methyltransferase Avira from Streptomyces Viridochromogenes J.Mol.Biol., 329, 2003
1PK2	SOLUTION STRUCTURE OF THE TISSUE-TYPE PLASMINOGEN ACTIVATOR KRINGLE 2 DOMAIN COMPLEXED TO 6-AMINOHEXANOIC ACID AN ANTIFIBRINOLYTIC DRUG 分子名称: 6-AMINOHEXANOIC ACID, TISSUE-TYPE PLASMINOGEN ACTIVATOR 著者 Llinas, M, Byeon, I.-J.L. 登録日 1991-09-16 公開日 1994-01-31 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of the tissue-type plasminogen activator kringle 2 domain complexed to 6-aminohexanoic acid an antifibrinolytic drug. J.Mol.Biol., 222, 1991
3RPG	Bmi1/Ring1b-UbcH5c complex structure 分子名称: E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1, Ubiquitin-conjugating enzyme E2 D3, ... 著者 Bentley, M.L, Dong, K.C, Cochran, A.G. 登録日 2011-04-26 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6485 Å) 主引用文献 Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex. Embo J., 30, 2011
6L53	Structure of SMG1 分子名称: Serine/threonine-protein kinase SMG1 著者 Xu, Y, Qi, Y. 登録日 2019-10-22 公開日 2020-04-15 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.63 Å) 主引用文献 Cryo-EM structure of SMG1-SMG8-SMG9 complex. Cell Res., 29, 2019
3HV4	Human p38 MAP Kinase in Complex with RL51 分子名称: 1-{3-[(6-aminoquinolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mitogen-activated protein kinase 14, ... 著者 Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. 登録日 2009-06-15 公開日 2009-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Displacement assay for the detection of stabilizers of inactive kinase conformations. J.Med.Chem., 53, 2010
3HL7	Crystal Structure of Human p38alpha complexed with SD-0006 分子名称: 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, 2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol, Mitogen-activated protein kinase 14 著者 Shieh, H.-S, Kurumbail, R.G, Stegeman, R.A, Williams, J.M. 登録日 2009-05-26 公開日 2009-07-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural bioinformatics-based prediction of exceptional selectivity of p38 MAP kinase inhibitor PH-797804. Biochemistry, 48, 2009
3HLL	Crystal Structure of Human p38alpha complexed with PH-797804 分子名称: 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide, HYPOPHOSPHITE, ... 著者 Shieh, H.-S, Williams, J.M, Stegeman, R.A, Kurumbail, R.G. 登録日 2009-05-27 公開日 2009-07-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural bioinformatics-based prediction of exceptional selectivity of p38 MAP kinase inhibitor PH-797804. Biochemistry, 48, 2009
3HL8	Crystal structure of exonuclease I in complex with inhibitor BCBP 分子名称: (5R)-3-tert-butyl-1-(6-chloro-1,3-benzothiazol-2-yl)-4,5-dihydro-1H-pyrazol-5-ol, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... 著者 Satyshur, K.A. 登録日 2009-05-27 公開日 2010-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Small-molecule tools for dissecting the roles of SSB/protein interactions in genome maintenance Proc.Natl.Acad.Sci.USA, 107, 2010
1WBT	Identification of novel p38 alpha MAP Kinase inhibitors using fragment-based lead generation. 分子名称: 3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE, MITOGEN-ACTIVATED PROTEIN KINASE 14 著者 Tickle, J, Cleasby, A, Devine, L.A, Jhoti, H. 登録日 2004-11-05 公開日 2005-11-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Identification of Novel P38Alpha Map Kinase Inhibitors Using Fragment-Based Lead Generation. J.Med.Chem., 48, 2005
1WC8	The crystal structure of mouse bet3p 分子名称: MYRISTIC ACID, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT3 著者 Kim, Y.-G, Sacher, M, Oh, B.-H. 登録日 2004-11-10 公開日 2004-12-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Bet3 Reveals a Novel Mechanism for Golgi Localization of Tethering Factor Trapp Nat.Struct.Mol.Biol., 12, 2005
3HP9	Crystal structure of SSB/Exonuclease I in complex with inhibitor CFAM 分子名称: 1,2-ETHANEDIOL, 2-{[2-chloro-5-(trifluoromethyl)phenyl]amino}-5-methoxybenzoic acid, DIMETHYL SULFOXIDE, ... 著者 Satyshur, K.A. 登録日 2009-06-03 公開日 2010-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Small-molecule tools for dissecting the roles of SSB/protein interactions in genome maintenance Proc.Natl.Acad.Sci.USA, 107, 2010
1WI4	Solution structure of the PDZ domain of syntaxin binding protein 4 分子名称: syntaxin binding protein 4 著者 Endo, H, Tomizawa, T, Kigawa, T, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-28 公開日 2005-06-07 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the PDZ domain of syntaxin binding protein 4 To be published
3HUB	Human p38 MAP Kinase in Complex with Scios-469 分子名称: 2-(6-chloro-5-{[(2R,5S)-4-(4-fluorobenzyl)-2,5-dimethylpiperazin-1-yl]carbonyl}-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Gruetter, C, Simard, J.R, Rauh, D. 登録日 2009-06-13 公開日 2010-03-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Fluorophore labeling of the glycine-rich loop as a method of identifying inhibitors that bind to active and inactive kinase conformations. J.Am.Chem.Soc., 132, 2010
6DLN	Oligomeric Structure of the HIV gp41 MPER-TMD in Phospholipid Bilayers 分子名称: Transmembrane protein gp41 著者 Kwon, B, Lee, M, Waring, A.J, Hong, M. 登録日 2018-06-01 公開日 2018-08-08 最終更新日 2024-05-01 実験手法 SOLID-STATE NMR 主引用文献 Oligomeric Structure and Three-Dimensional Fold of the HIV gp41 Membrane-Proximal External Region and Transmembrane Domain in Phospholipid Bilayers. J. Am. Chem. Soc., 140, 2018
3HUF	Structure of the S. pombe Nbs1-Ctp1 complex 分子名称: DNA repair and telomere maintenance protein nbs1, Double-strand break repair protein ctp1, THIOCYANATE ION 著者 Williams, R.S, Guenther, G, Tainer, J.A. 登録日 2009-06-13 公開日 2009-10-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair. Cell(Cambridge,Mass.), 139, 2009
3HSU	Functional roles of the 6-s-cysteinyl, 8 alpha-N1-histidyl FAD in Glucooligosaccharide Oxidase from Acremonium strictum 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Liaw, S.-H, Huang, C.-H. 登録日 2009-06-10 公開日 2009-06-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Functional roles of the 6-S-cysteinyl, 8alpha-N1-histidyl FAD in glucooligosaccharide oxidase from Acremonium strictum J.Biol.Chem., 283, 2008
3HTX	Crystal structure of small RNA methyltransferase HEN1 分子名称: 5'-R(*GP*AP*UP*UP*UP*CP*UP*CP*UP*CP*UP*GP*CP*AP*AP*GP*CP*GP*AP*AP*AP*G)-3', 5'-R(P*UP*UP*CP*GP*CP*UP*UP*GP*CP*AP*GP*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*C)-3', HEN1, ... 著者 Huang, Y, Ji, L.-J, Huang, Q.-C, Vassylyev, D.G, Chen, X.-M, Ma, J.-B. 登録日 2009-06-12 公開日 2009-09-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural insights into mechanisms of the small RNA methyltransferase HEN1. Nature, 461, 2009
1WKQ	Crystal Structure of Bacillus subtilis Guanine Deaminase. The first domain-swapped structure in the cytidine deaminase superfamily 分子名称: Guanine deaminase, IMIDAZOLE, ZINC ION 著者 Liaw, S.H, Chang, Y.J, Lai, C.T. 登録日 2004-06-01 公開日 2004-07-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Crystal Structure of Bacillus subtilis Guanine Deaminase: THE FIRST DOMAIN-SWAPPED STRUCTURE IN THE CYTIDINE DEAMINASE SUPERFAMILY J.Biol.Chem., 279, 2004
1WC9	The crystal structure of truncated mouse bet3p 分子名称: GLYCEROL, MYRISTIC ACID, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT3 著者 Kim, Y.-G, Lee, H.-S, Sacher, M, Oh, B.-H. 登録日 2004-11-10 公開日 2004-12-13 最終更新日 2015-04-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of Bet3 Reveals a Novel Mechanism for Golgi Localization of Tethering Factor Trapp Nat.Struct.Mol.Biol., 12, 2005

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