6XJD
 
 | | Two mouse cGAS catalytic domain binding to human assembled nucleosome | | 分子名称: | Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... | | 著者 | Xu, P, Li, P, Zhao, B. | | 登録日 | 2020-06-23 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | | 主引用文献 | The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020
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1MYP
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5WKY
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1N18
 | | Thermostable mutant of Human Superoxide Dismutase, C6A, C111S | | 分子名称: | COPPER (I) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ... | | 著者 | Cardoso, R.M.F, Thayer, M.M, DiDonato, M, Lo, T.P, Bruns, C.K, Getzoff, E.D, Tainer, J.A. | | 登録日 | 2002-10-16 | | 公開日 | 2002-11-27 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase.
J.Mol.Biol., 324, 2002
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1W37
 | | 2-keto-3-deoxygluconate(KDG) aldolase of Sulfolobus solfataricus | | 分子名称: | 2-KETO-3-DEOXY GLUCONATE ALDOLASE, GLYCEROL, SODIUM ION | | 著者 | Theodossis, A, Walden, H, Westwick, E.J, Connaris, H, Lamble, H.J, Hough, D.W, Danson, M.J, Taylor, G.L. | | 登録日 | 2004-07-13 | | 公開日 | 2004-09-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus.
J. Biol. Chem., 279, 2004
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3VQ6
 | | HIV-1 IN core domain in complex with (1-methyl-5-phenyl-1H-pyrazol-4-yl)methanol | | 分子名称: | (1-methyl-5-phenyl-1H-pyrazol-4-yl)methanol, CADMIUM ION, POL polyprotein, ... | | 著者 | Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. | | 登録日 | 2012-03-20 | | 公開日 | 2013-01-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
J Biomol Screen, 18, 2013
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5AC8
 | | S. enterica HisA with mutations D10G, dup13-15, G102A | | 分子名称: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, SULFATE ION | | 著者 | Newton, M, Guo, X, Soderholm, A, Nasvall, J, Andersson, D, Patrick, W, Selmer, M. | | 登録日 | 2015-08-12 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | | 主引用文献 | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6XKM
 | | Room Temperature Structure of SARS-CoV-2 NSP10/NSP16 Methyltransferase in a Complex with SAM Determined by Fixed-Target Serial Crystallography | | 分子名称: | 2'-O-methyltransferase, CHLORIDE ION, Non-structural protein 10, ... | | 著者 | Wilamowski, M, Sherrell, D.A, Minasov, G, Kim, Y, Shuvalova, L, Lavens, A, Chard, R, Rosas-Lemus, M, Maltseva, N, Jedrzejczak, R, Michalska, K, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-06-26 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | 2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography.
Proc.Natl.Acad.Sci.USA, 118, 2021
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5AB0
 | | Crystal structure of aminopeptidase ERAP2 with ligand | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Mpakali, A, Giastas, P, Saridakis, E, Stratikos, E. | | 登録日 | 2015-07-31 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (Er) Aminopeptidase 2.
J.Biol.Chem., 290, 2015
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1W61
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2BR6
 | | Crystal Structure of Quorum-Quenching N-Acyl Homoserine Lactone Lactonase | | 分子名称: | AIIA-LIKE PROTEIN, GLYCEROL, HOMOSERINE LACTONE, ... | | 著者 | Kim, M.H, Choi, W.C, Kang, H.O, Kang, B.S, Kim, K.J, Derewenda, Z.S, Lee, J.K, Oh, T.K, Lee, C.H. | | 登録日 | 2005-05-03 | | 公開日 | 2005-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Molecular Structure and Catalytic Mechanism of a Quorum-Quenching N-Acyl-L-Homoserine Lactone Hydrolase.
Proc.Natl.Acad.Sci.USA, 102, 2005
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3VLY
 | | Assimilatory nitrite reductase (Nii3) - N226K mutant - SO3 partial complex from tobacco leaf | | 分子名称: | CHLORIDE ION, IRON/SULFUR CLUSTER, Nitrite reductase, ... | | 著者 | Nakano, S, Takahashi, M, Sakamoto, A, Morikawa, H, Katayanagi, K. | | 登録日 | 2011-12-05 | | 公開日 | 2012-09-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | X-ray crystal structure of a mutant assimilatory nitrite reductase that shows sulfite reductase-like activity
Chem.Biodivers., 9, 2012
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1W3B
 | | The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha. | | 分子名称: | CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 | | 著者 | Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E. | | 登録日 | 2004-07-14 | | 公開日 | 2004-09-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
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1S60
 | | Aminoglycoside N-Acetyltransferase AAC(6')-Iy in Complex with CoA and N-terminal His(6)-tag (crystal form 2) | | 分子名称: | COENZYME A, SULFATE ION, aminoglycoside 6'-N-acetyltransferase | | 著者 | Vetting, M.W, Magnet, S, Nieves, E, Roderick, S.L, Blanchard, J.S. | | 登録日 | 2004-01-22 | | 公開日 | 2004-05-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones
Chem.Biol., 11, 2004
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6XMJ
 | | Human 20S proteasome bound to an engineered 11S (PA26) activator | | 分子名称: | Proteasome activator protein PA26, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | | 著者 | de la Pena, A.H, Opoku-Nsiah, K.A, Williams, S.K, Chopra, N, Sali, A, Gestwicki, J.E, Lander, G.C. | | 登録日 | 2020-06-30 | | 公開日 | 2020-07-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | The Y Phi motif defines the structure-activity relationships of human 20S proteasome activators.
Nat Commun, 13, 2022
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5WTL
 | | Crystal structure of the periplasmic portion of outer membrane protein A (OmpA) from Capnocytophaga gingivalis | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, OmpA family protein, ... | | 著者 | Dai, S, Tan, K, Ye, S, Zhang, R. | | 登録日 | 2016-12-13 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Structure of thrombospondin type 3 repeats in bacterial outer membrane protein A reveals its intra-repeat disulfide bond-dependent calcium-binding capability.
Cell Calcium, 66, 2017
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1N1D
 | | Glycerol-3-phosphate cytidylyltransferase complexed with CDP-glycerol | | 分子名称: | SULFATE ION, [CYTIDINE-5'-PHOSPHATE] GLYCERYLPHOSPHORIC ACID ESTER, glycerol-3-phosphate cytidylyltransferase | | 著者 | Pattridge, K.A, Weber, C.H, Friesen, J.A, Sankar, S, Kent, C, Ludwig, M.L. | | 登録日 | 2002-10-17 | | 公開日 | 2003-11-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Glycerol-3-phosphate cytidylyltransferase. Structural changes induced by binding of CDP-glycerol and the role of lysine residues in catalysis
J.Biol.Chem., 278, 2003
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1N4E
 | | Crystal Structure of a DNA Decamer Containing a Thymine-dimer | | 分子名称: | 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3' | | 著者 | Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.-S, Kang, C. | | 登録日 | 2002-10-30 | | 公開日 | 2003-02-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a DNA decamer containing a cis-syn thymine dimer.
Proc.Natl.Acad.Sci.USA, 99, 2002
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5AI7
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1MSJ
 | | TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T15V | | 分子名称: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | | 著者 | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | | 登録日 | 1999-01-24 | | 公開日 | 1999-04-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Quantitative and qualitative analysis of type III antifreeze protein structure and function.
J.Biol.Chem., 274, 1999
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1N3A
 | | Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase | | 分子名称: | CALCIUM ION, DNA complement strand, DNA inhibitor strand, ... | | 著者 | Norman, D.P, Chung, S.J, Verdine, G.L. | | 登録日 | 2002-10-25 | | 公開日 | 2003-03-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase
Biochemistry, 42, 2003
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3VOZ
 | | Crystal structure of human glutaminase in complex with BPTES | | 分子名称: | Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide), ... | | 著者 | Thangavelu, K, Sivaraman, J. | | 登録日 | 2012-02-23 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VUO
 | | Crystal structure of nontoxic nonhemagglutinin subcomponent (NTNHA) from clostridium botulinum serotype D strain 4947 | | 分子名称: | NTNHA | | 著者 | Sagane, Y, Miyashita, S.-I, Miyata, K, Matsumoto, T, Inui, K, Hayashi, S, Suzuki, T, Hasegawa, K, Yajima, S, Yamano, A, Niwa, K, Watanabe, T. | | 登録日 | 2012-07-03 | | 公開日 | 2012-09-19 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Small-angle X-ray scattering reveals structural dynamics of the botulinum neurotoxin associating protein, nontoxic nonhemagglutinin
Biochem.Biophys.Res.Commun., 425, 2012
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1W2X
 | | Crystal structure of the carboxyltransferase domain of acetyl- coenzyme A carboxylase in complex with CP-640186 | | 分子名称: | (3R)-1'-(9-ANTHRYLCARBONYL)-3-(MORPHOLIN-4-YLCARBONYL)-1,4'-BIPIPERIDINE, ACETYL-COA CARBOXYLASE | | 著者 | Zhang, H, Tweel, B, Li, J, Tong, L. | | 登録日 | 2004-07-09 | | 公開日 | 2004-09-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of the Carboxyltransferase Domain of Acetyl-Coenzyme a Carboxylase in Complex with Cp-640186
Structure, 12, 2004
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3VQC
 | | HIV-1 IN core domain in complex with (5-METHYL-3-PHENYL-1,2-OXAZOL-4-YL)METHANOL | | 分子名称: | (5-methyl-3-phenyl-1,2-oxazol-4-yl)methanol, CADMIUM ION, POL polyprotein, ... | | 著者 | Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. | | 登録日 | 2012-03-21 | | 公開日 | 2013-01-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
J Biomol Screen, 18, 2013
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