6YKD
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![BU of 6ykd by Molmil](/molmil-images/mine/6ykd) | Human Pim-1 kinase in complex with an inhibitor identified by virtual screening | 分子名称: | ACETATE ION, GLYCEROL, Serine/threonine-protein kinase pim-1, ... | 著者 | Schneider, P, Welin, M, Svensson, B, Walse, B, Schneider, G. | 登録日 | 2020-04-06 | 公開日 | 2020-07-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Virtual Screening and Design with Machine Intelligence Applied to Pim-1 Kinase Inhibitors. Mol Inform, 39, 2020
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8OZN
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8OZL
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8OZK
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7T7A
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![BU of 7t7a by Molmil](/molmil-images/mine/7t7a) | Crystal Structure of Human SHOC2: A Leucine-Rich Repeat Protein | 分子名称: | Leucine-rich repeat protein SHOC-2, MAGNESIUM ION, NITRATE ION | 著者 | Hajian, B, Lemke, C, Kwon, J, Bian, Y, Fuller, C, Aguirre, J. | 登録日 | 2021-12-14 | 公開日 | 2022-05-04 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex. Nature, 609, 2022
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8CWM
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7B17
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![BU of 7b17 by Molmil](/molmil-images/mine/7b17) | SARS-CoV-spike RBD bound to two neutralising nanobodies. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama,SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama, Spike protein S1 | 著者 | Hallberg, B.M, Das, H. | 登録日 | 2020-11-23 | 公開日 | 2021-02-10 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (4.01 Å) | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape Science, 371, 2021
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6OUO
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![BU of 6ouo by Molmil](/molmil-images/mine/6ouo) | RF2 accommodated state bound 70S complex at long incubation time | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | 登録日 | 2019-05-05 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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4X5P
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![BU of 4x5p by Molmil](/molmil-images/mine/4x5p) | Crystal structure of FimH in complex with a benzoyl-amidophenyl alpha-D-mannopyranoside | 分子名称: | 4-{[3-chloro-4-(alpha-D-mannopyranosyloxy)phenyl]carbamoyl}benzoic acid, Protein FimH | 著者 | Preston, R.C, Jakob, R.P, Fiege, B, Zihlmann, P, Rabbani, S, Schwardt, O, Jiang, X, Ernst, B, Maier, T. | 登録日 | 2014-12-05 | 公開日 | 2015-05-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (0.997 Å) | 主引用文献 | The Tyrosine Gate of the Bacterial Lectin FimH: A Conformational Analysis by NMR Spectroscopy and X-ray Crystallography. Chembiochem, 16, 2015
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6YR4
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![BU of 6yr4 by Molmil](/molmil-images/mine/6yr4) | Dye-type peroxidase DtpB in the ferryl state: Spectroscopically Validated composite structure | 分子名称: | MAGNESIUM ION, OXYGEN ATOM, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Lucic, M, Dworkowski, F.S.N, Worrall, J.A.R, Hough, M.A. | 登録日 | 2020-04-19 | 公開日 | 2021-01-13 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Serial Femtosecond Zero Dose Crystallography Captures a Water-Free Distal Heme Site in a Dye-Decolorising Peroxidase to Reveal a Catalytic Role for an Arginine in Fe IV =O Formation. Angew.Chem.Int.Ed.Engl., 59, 2020
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1BDW
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6M2I
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![BU of 6m2i by Molmil](/molmil-images/mine/6m2i) | Structure of the 2-Aminoisobutyric acid Monooxygenase Hydroxylase | 分子名称: | 1,2-ETHANEDIOL, Amidohydrolase, FE (III) ION, ... | 著者 | Hibi, M, Mikami, B, Ogawa, J. | 登録日 | 2020-02-27 | 公開日 | 2021-01-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | A three-component monooxygenase from Rhodococcus wratislaviensis may expand industrial applications of bacterial enzymes. Commun Biol, 4, 2021
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7TBM
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![BU of 7tbm by Molmil](/molmil-images/mine/7tbm) | Composite structure of the dilated human nuclear pore complex (NPC) generated with a 37A in situ cryo-ET map of CD4+ T cell NPC | 分子名称: | DDX19, NUP107 CTD, NUP107 NTD, ... | 著者 | Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. | 登録日 | 2021-12-22 | 公開日 | 2022-06-15 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (37 Å) | 主引用文献 | Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
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7TBK
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![BU of 7tbk by Molmil](/molmil-images/mine/7tbk) | Composite structure of the dilated human nuclear pore complex (NPC) symmetric core generated with a 37A in situ cryo-ET map of CD4+ T cell NPC | 分子名称: | NUP107 CTD, NUP107 NTD, NUP133, ... | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | 登録日 | 2021-12-22 | 公開日 | 2022-06-15 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (37 Å) | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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7TBI
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![BU of 7tbi by Molmil](/molmil-images/mine/7tbi) | Composite structure of the S. cerevisiae nuclear pore complex (NPC) | 分子名称: | Dyn2, Nic96 R1, Nic96 R2, ... | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | 登録日 | 2021-12-22 | 公開日 | 2022-06-15 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (25 Å) | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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6UYD
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![BU of 6uyd by Molmil](/molmil-images/mine/6uyd) | Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v1 redesigned core from genotype 1a bound to broadly neutralizing antibody AR3C | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | 著者 | Tzarum, N, Wilson, I.A, Zhu, J. | 登録日 | 2019-11-13 | 公開日 | 2020-04-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | 主引用文献 | Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines. Sci Adv, 6, 2020
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7SQ4
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![BU of 7sq4 by Molmil](/molmil-images/mine/7sq4) | Designed trefoil knot protein, variant 2 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Designed trefoil knot protein, variant 2, ... | 著者 | Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. | 登録日 | 2021-11-04 | 公開日 | 2022-06-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.493 Å) | 主引用文献 | De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
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8PN6
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![BU of 8pn6 by Molmil](/molmil-images/mine/8pn6) | Crystal Structure of co-expressed NS2B-NS3 Protease from Zika Virus | 分子名称: | Genome polyprotein, Serine protease subunit NS2B | 著者 | Ni, X, Fairhead, M, Balcomb, B.H, Aschenbrenner, J.C, Ferreira, L.M, Godoy, A.S, Lithgo, R.M, MacLean, E.M, Marples, P.G, Thompson, W, Tomlinson, C.W.E, Szommer, T, Wild, C, Wright, N.D, Koekemoer, L, Fearon, D, Walsh, M.A, von Delft, F. | 登録日 | 2023-06-29 | 公開日 | 2023-08-16 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Crystal Structure of co-expressed NS2B-NS3 Protease from Zika Virus To Be Published
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7SQ3
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![BU of 7sq3 by Molmil](/molmil-images/mine/7sq3) | Designed trefoil knot protein, variant 1 | 分子名称: | CHLORIDE ION, Designed trefoil knot protein, variant 1, ... | 著者 | Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. | 登録日 | 2021-11-04 | 公開日 | 2022-06-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.453 Å) | 主引用文献 | De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
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7AGY
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7AHT
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7AGW
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7TFA
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![BU of 7tfa by Molmil](/molmil-images/mine/7tfa) | P. polymyxa GS(12)-Q-GlnR peptide | 分子名称: | GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ... | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | 登録日 | 2022-01-06 | 公開日 | 2022-06-29 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.07 Å) | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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7TF6
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![BU of 7tf6 by Molmil](/molmil-images/mine/7tf6) | S. aureus GS(12)-Q-GlnR peptide | 分子名称: | GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | 登録日 | 2022-01-06 | 公開日 | 2022-06-29 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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7TFE
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![BU of 7tfe by Molmil](/molmil-images/mine/7tfe) | L. monocytogenes GS(12) - apo | 分子名称: | Glutamine synthetase, MAGNESIUM ION | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | 登録日 | 2022-01-06 | 公開日 | 2022-06-29 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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