2DK7
 
 | | Solution structure of WW domain in transcription elongation regulator 1 | | 分子名称: | Transcription elongation regulator 1 | | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-06 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of WW domain in transcription elongation regulator 1
To be Published
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2DMQ
 | | Solution structure of the homeobox domain of LIM/homeobox protein Lhx9 | | 分子名称: | LIM/homeobox protein Lhx9 | | 著者 | Ohnishi, S, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-24 | | 公開日 | 2006-10-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the homeobox domain of LIM/homeobox protein Lhx9
To be Published
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2DUV
 | | Structure of CDK2 with a 3-hydroxychromones | | 分子名称: | 2-(3,4-DIHYDROXYPHENYL)-8-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-3-HYDROXY-6-METHYL-4H-CHROMEN-4-ONE, Cell division protein kinase 2 | | 著者 | Kim, K.H, Lee, J, Park, T, Jeong, S, Hong, C. | | 登録日 | 2006-07-27 | | 公開日 | 2007-01-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | 3-Hydroxychromones as cyclin-dependent kinase inhibitors: synthesis and biological evaluation.
Bioorg.Med.Chem.Lett., 17, 2007
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2DOD
 | | Solution structure of the first FF domain of human transcription factor CA150 | | 分子名称: | Transcription elongation regulator 1 | | 著者 | Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-28 | | 公開日 | 2006-10-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the first FF domain of human transcription factor CA150
To be Published
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2DS1
 | | Human cyclin dependent kinase 2 complexed with the CDK4 inhibitor | | 分子名称: | (13R,15S)-13-METHYL-16-OXA-8,9,12,22,24-PENTAAZAHEXACYCLO[15.6.2.16,9.1,12,15.0,2,7.0,21,25]HEPTACOSA-1(24),2,4,6,17(25 ),18,20-HEPTAENE-23,26-DIONE, Cell division protein kinase 2 | | 著者 | Ikuta, M. | | 登録日 | 2006-06-17 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure
Bioorg.Med.Chem.Lett., 16, 2006
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2DMS
 | | Solution structure of the homeobox domain of Homeobox protein OTX2 | | 分子名称: | Homeobox protein OTX2 | | 著者 | Ohnishi, S, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-24 | | 公開日 | 2006-10-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the homeobox domain of Homeobox protein OTX2
To be Published
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2E5B
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4EWA
 | | Study on structure and function relationships in human Pirin with Fe ion | | 分子名称: | FE (III) ION, Pirin | | 著者 | Liu, F, Rehmani, I, Chen, L, Fu, R, Serrano, V, Wilson, D.W, Liu, A. | | 登録日 | 2012-04-26 | | 公開日 | 2013-05-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Pirin is an iron-dependent redox regulator of NF-kappa B.
Proc.Natl.Acad.Sci.USA, 110, 2013
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7C6S
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4ELJ
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1PCF
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4EZ3
 | | CDK2 in complex with NSC 134199 | | 分子名称: | 1,2-ETHANEDIOL, 4-[(E)-(6-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)diazenyl]benzenesulfonamide, Cyclin-dependent kinase 2 | | 著者 | Alam, R, Martin, M, Zhu, J.-Y, Schonbrunn, E. | | 登録日 | 2012-05-02 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2.
Chembiochem, 13, 2012
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4F3I
 | | Crystal structure of the first bromodomain of human BRD4 in complex with MS417 inhibitor | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, methyl [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate | | 著者 | Joshua, J, Zhou, M.-M, Plotnikov, A.N. | | 登録日 | 2012-05-09 | | 公開日 | 2012-09-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Down-regulation of NF-{kappa}B Transcriptional Activity in HIV-associated Kidney Disease by BRD4 Inhibition.
J.Biol.Chem., 287, 2012
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4EZ7
 | | CDK2 in complex with staurosporine and 2 molecules of 8-anilino-1-naphthalene sulfonic acid | | 分子名称: | 1,2-ETHANEDIOL, 8-ANILINO-1-NAPHTHALENE SULFONATE, Cyclin-dependent kinase 2, ... | | 著者 | Alam, R, Martin, M.P, Zhu, J.-Y, Schonbrunn, E. | | 登録日 | 2012-05-02 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2.
Chembiochem, 13, 2012
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4EZ5
 | | CDK6 (monomeric) in complex with inhibitor | | 分子名称: | Cyclin-dependent kinase 6, {5-[4-(dimethylamino)piperidin-1-yl]-1H-imidazo[4,5-b]pyridin-2-yl}[2-(isoquinolin-4-yl)pyridin-4-yl]methanone | | 著者 | Chopra, R, Xu, M. | | 登録日 | 2012-05-02 | | 公開日 | 2013-02-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors.
ACS Med Chem Lett, 3, 2012
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4F52
 | | Structure of a Glomulin-RBX1-CUL1 complex | | 分子名称: | Cullin-1, E3 ubiquitin-protein ligase RBX1, Glomulin, ... | | 著者 | Duda, D.M, Olszewski, J.L, Schulman, B.A. | | 登録日 | 2012-05-11 | | 公開日 | 2012-09-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface.
Mol.Cell, 47, 2012
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4G8W
 | | Rat Heme Oxygenase-1 in complex with Heme and O2 with 13 hr illumination: Laser on | | 分子名称: | FORMIC ACID, Heme oxygenase 1, OXYGEN MOLECULE, ... | | 著者 | Sugishima, M, Moffat, K, Noguchi, M. | | 登録日 | 2012-07-23 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis.
Biochemistry, 51, 2012
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7MKX
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4G98
 | | Rat Heme Oxygenase-1 in complex with Heme and CO at 100K | | 分子名称: | CARBON MONOXIDE, FORMIC ACID, Heme oxygenase 1, ... | | 著者 | Sugishima, M, Moffat, K, Noguchi, M. | | 登録日 | 2012-07-23 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis.
Biochemistry, 51, 2012
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7NFW
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3D87
 | | Crystal structure of Interleukin-23 | | 分子名称: | Interleukin-12 subunit p40, Interleukin-23 subunit p19, PHOSPHATE ION, ... | | 著者 | Beyer, B.M, Ingram, R, Ramanathan, L, Reichert, P, Le, H, Madison, V. | | 登録日 | 2008-05-22 | | 公開日 | 2008-09-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibody
J.Mol.Biol., 382, 2008
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4G7T
 | | Rat Heme Oxygenase-1 in complex with Heme and CO with 1 hr Illumination: Laser on | | 分子名称: | CARBON MONOXIDE, FORMIC ACID, Heme oxygenase 1, ... | | 著者 | Sugishima, M, Moffat, K, Noguchi, M. | | 登録日 | 2012-07-20 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis.
Biochemistry, 51, 2012
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4G8U
 | | Rat Heme Oxygenase-1 in complex with Heme and O2 with 13 hr illumination: Laser off | | 分子名称: | FORMIC ACID, Heme oxygenase 1, OXYGEN MOLECULE, ... | | 著者 | Sugishima, M, Moffat, K, Noguchi, M. | | 登録日 | 2012-07-23 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis.
Biochemistry, 51, 2012
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4G91
 | | CCAAT-binding complex from Aspergillus nidulans | | 分子名称: | HAPB protein, HapE, Transcription factor HapC (Eurofung) | | 著者 | Huber, E.M, Scharf, D.H, Hortschansky, P, Groll, M, Brakhage, A.A. | | 登録日 | 2012-07-23 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | DNA Minor Groove Sensing and Widening by the CCAAT-Binding Complex.
Structure, 20, 2012
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4B21
 | | Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2 | | 分子名称: | 5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*GP*AP*TP*CP*GP)-3', PHOSPHATE ION, ... | | 著者 | Dalhus, B, Nilsen, L, Korvald, H, Huffman, J, Forstrom, R.J, McMurray, C.T, Alseth, I, Tainer, J.A, Bjoras, M. | | 登録日 | 2012-07-12 | | 公開日 | 2013-01-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2.
Structure, 21, 2013
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