CDK2 in complex with NSC 134199

Summary for 4EZ3

Related4ERW 4EZ7
DescriptorCyclin-dependent kinase 2, 4-[(E)-(6-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)diazenyl]benzenesulfonamide, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsprotein kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton, centrosome P24941
Total number of polymer chains1
Total molecular weight35117.7
Alam, R.,Martin, M.,Zhu, J.-Y.,Schonbrunn, E. (deposition date: 2012-05-02, release date: 2012-08-22, Last modification date: 2012-10-03)
Primary citation
Martin, M.P.,Alam, R.,Betzi, S.,Ingles, D.J.,Zhu, J.Y.,Schonbrunn, E.
A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2.
Chembiochem, 13:2128-2136, 2012
PubMed: 22893598 (PDB entries with the same primary citation)
DOI: 10.1002/cbic.201200316
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24413 0.3% 0.8% 11.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28