2H1B
| ResA E80Q | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Thiol-disulfide oxidoreductase resA | 著者 | Lewin, A, Crow, A, Oubrie, A, Le Brun, N.E. | 登録日 | 2006-05-16 | 公開日 | 2006-09-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Molecular Basis for Specificity of the Extracytoplasmic Thioredoxin ResA. J.Biol.Chem., 281, 2006
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3DKL
| Crystal structure of phosphorylated mimic form of human NAMPT complexed with benzamide and phosphoribosyl pyrophosphate | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, BENZAMIDE, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Ho, M, Burgos, E.S, Almo, S.C, Schramm, V.L. | 登録日 | 2008-06-25 | 公開日 | 2009-08-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT. Proc.Natl.Acad.Sci.USA, 106, 2009
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4H4F
| Crystal structure of human chymotrypsin C (CTRC) bound to inhibitor eglin c from Hirudo medicinalis | 分子名称: | Chymotrypsin-C, Eglin C, PHOSPHATE ION | 著者 | Batra, J, Soares, A.S, Radisky, E.S. | 登録日 | 2012-09-17 | 公開日 | 2013-02-27 | 最終更新日 | 2013-04-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Long-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme Activation. J.Biol.Chem., 288, 2013
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4H4O
| Crystal Structure of HIV-1 Reverse Transcriptase (RT) in Complex with (E)-3-(3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)- 4-fluorophenoxy)-5-fluorophenyl)acrylonitrile (JLJ506), A Non-nucleoside inhibitor | 分子名称: | (2E)-3-(3-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]-4-fluorophenoxy}-5-fluorophenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, Exoribonuclease H, ... | 著者 | Frey, K.M, Anderson, K.S. | 登録日 | 2012-09-17 | 公開日 | 2012-12-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structures of HIV-1 Reverse Transcriptase with Picomolar Inhibitors Reveal Key Interactions for Drug Design. J.Am.Chem.Soc., 134, 2012
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2H2B
| Crystal Structure of ZO-1 PDZ1 Bound to a Phage-Derived Ligand (WRRTTYL) | 分子名称: | ACETIC ACID, Tight junction protein ZO-1 | 著者 | Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. | 登録日 | 2006-05-18 | 公開日 | 2006-06-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity. J.Biol.Chem., 281, 2006
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3M9Y
| Crystal structure of Triosephosphate isomerase from methicillin resistant Staphylococcus aureus at 1.9 Angstrom resolution | 分子名称: | CITRIC ACID, SODIUM ION, Triosephosphate isomerase | 著者 | Mukherjee, S, Dutta, D, Saha, B, Das, A.K. | 登録日 | 2010-03-23 | 公開日 | 2011-04-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of triosephosphate isomerase from methicillin resistant Staphylococcus aureus MRSA252 provide structural insights into novel modes of ligand binding and unique conformations of catalytic loop Biochimie, 94, 2012
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2PLW
| Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052). | 分子名称: | Ribosomal RNA methyltransferase, putative, S-ADENOSYLMETHIONINE, ... | 著者 | Wernimont, A.K, Hassanali, A, Lin, L, Lew, J, Zhao, Y, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Schapira, M, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Qiu, W, Structural Genomics Consortium (SGC) | 登録日 | 2007-04-20 | 公開日 | 2007-05-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052). To be Published
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3MP8
| Crystal structure of Sgf29 tudor domain | 分子名称: | 4-(HYDROXYMETHYL)BENZAMIDINE, ACETIC ACID, GLYCEROL, ... | 著者 | Li, J, Wu, M, Ruan, J, Zang, J. | 登録日 | 2010-04-26 | 公開日 | 2011-05-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation Embo J., 30, 2011
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3MAD
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4LXM
| Crystal Structure of Human Beta Secretase in Complex with compound 12a | 分子名称: | (1S,3S,4S,5R)-3-{4-amino-3-fluoro-5-[(1,1,1,3,3,3-hexafluoropropan-2-yl)oxy]benzyl}-5-[(3-tert-butylbenzyl)amino]tetrahydro-2H-thiopyran-4-ol 1-oxide, Beta-secretase 1 | 著者 | Rondeau, J.M, Bourgier, E. | 登録日 | 2013-07-30 | 公開日 | 2013-08-28 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective beta-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid beta-peptides. Bioorg.Med.Chem.Lett., 23, 2013
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2B9D
| Crystal Structure of HPV E7 CR3 domain | 分子名称: | E7 protein, ZINC ION | 著者 | Liu, X, Clements, A, Zhao, K, Marmorstein, R. | 登録日 | 2005-10-11 | 公開日 | 2005-10-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor. J.Biol.Chem., 281, 2006
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3GW3
| human UROD mutant K297N | 分子名称: | Uroporphyrinogen decarboxylase | 著者 | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | 登録日 | 2009-03-31 | 公開日 | 2009-07-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and kinetic characterization of mutant human uroporphyrinogen decarboxylases. Cell Mol Biol (Noisy-le-grand), 55, 2009
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2PWO
| Crystal Structure of HIV-1 CA146 A92E Psuedo Cell | 分子名称: | CHLORIDE ION, Gag-Pol polyprotein (Pr160Gag-Pol) | 著者 | Kelly, B.N. | 登録日 | 2007-05-11 | 公開日 | 2007-09-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein. J.Mol.Biol., 373, 2007
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3GWK
| Structure of the homodimeric WXG-100 family protein from Streptococcus agalactiae | 分子名称: | Putative uncharacterized protein SAG1039, SULFATE ION | 著者 | Poulsen, C, Gries, F, Wilmanns, M, Song, Y.H. | 登録日 | 2009-04-01 | 公開日 | 2010-09-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | WXG100 protein superfamily consists of three subfamilies and exhibits an alpha-helical C-terminal conserved residue pattern. Plos One, 9, 2014
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3MBB
| Crystal structure of StSPL - apo form, after treatment with semicarbazide | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ... | 著者 | Bourquin, F, Grutter, M.G, Capitani, G. | 登録日 | 2010-03-25 | 公開日 | 2010-08-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.051 Å) | 主引用文献 | Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. Structure, 18, 2010
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2PX7
| Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8 | 分子名称: | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase | 著者 | Chen, L, Tsukuda, M, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Chen, L.-Q, Liu, Z.-J, Lee, D, Chang, S.-H, Nguyen, D, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-14 | 公開日 | 2007-06-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8. To be Published
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3MCB
| Crystal structure of NAC domains of human nascent polypeptide-associated complex (NAC) | 分子名称: | IODIDE ION, Nascent polypeptide-associated complex subunit alpha, Transcription factor BTF3 | 著者 | Wang, L.F, Zhang, W.C, Wang, L, Zhang, X.J.C, Li, X.M, Rao, Z. | 登録日 | 2010-03-29 | 公開日 | 2010-07-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of NAC domains of human nascent polypeptide-associated complex (NAC) and its alphaNAC subunit Protein Cell, 1, 2010
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4HFO
| Biogenic amine-binding protein selenomethionine derivative | 分子名称: | Biogenic amine-binding protein | 著者 | Andersen, J.F, Xu, X, Chang, B, Mans, B.J, Ribeiro, J.M. | 登録日 | 2012-10-05 | 公開日 | 2013-01-02 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure and ligand-binding properties of the biogenic amine-binding protein from the saliva of a blood-feeding insect vector of Trypanosoma cruzi. Acta Crystallogr.,Sect.D, 69, 2013
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3MRK
| Crystal Structure of MHC class I HLA-A2 molecule complexed with AFP137 nonapeptide | 分子名称: | 9-meric peptide from Alpha-fetoprotein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal Structure of MHC class I HLA-A2 molecule complexed with AFP137 nonapeptide To be Published
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4LXB
| Crystal Structure Analysis of thrombin in complex with compound D58 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-difluoromethoxy-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-((S)-3-dimethylamino-pyrrolidin-1-yl)-3-oxo-propyl]-amide, Hirudin variant-1, ... | 著者 | Stehlin-Gaon, C, Bocskei, Z. | 登録日 | 2013-07-29 | 公開日 | 2014-06-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | 5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a selective and potent orally active dual thrombin and factor Xa inhibitor. J.Med.Chem., 56, 2013
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3GZ8
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2PXX
| Human putative methyltransferase MGC2408 | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN ATOM OR ION, Uncharacterized protein MGC2408 | 著者 | Tempel, W, Wu, H, Dombrovsky, L, Zeng, H, Zhu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | 登録日 | 2007-05-14 | 公開日 | 2007-05-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene. Proteins, 74, 2009
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4H89
| The Structure of a GCN5-Related N-Acetyltransferase from Kribbella flavida | 分子名称: | GCN5-related N-acetyltransferase | 著者 | Cuff, M.E, Mcknight, S.M, Mack, J.C, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2012-09-21 | 公開日 | 2012-10-10 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | The Structure of a GCN5-Related N-Acetyltransferase from Kribbella flavida. TO BE PUBLISHED
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3H0W
| Human AdoMetDC with 5'-Deoxy-5'-[(N-dimethyl)amino]-8-methyl-adenosine | 分子名称: | 1,4-DIAMINOBUTANE, 5'-deoxy-5'-(dimethylamino)-8-methyladenosine, PYRUVIC ACID, ... | 著者 | Bale, S, Brooks, W.H, Hanes, J.W, Mahesan, A.M, Guida, W.C, Ealick, S.E. | 登録日 | 2009-04-10 | 公開日 | 2009-06-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase. Biochemistry, 48, 2009
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3H3J
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