6MJP
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![BU of 6mjp by Molmil](/molmil-images/mine/6mjp) | LptB(E163Q)FGC from Vibrio cholerae | 分子名称: | 2-(2-ETHOXYETHOXY)ETHANOL, 6-cyclohexylhexyl beta-D-glucopyranoside, ABC transporter ATP-binding protein, ... | 著者 | Owens, T.W, Kahne, D, Kruse, A.C. | 登録日 | 2018-09-21 | 公開日 | 2019-03-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural basis of unidirectional export of lipopolysaccharide to the cell surface. Nature, 567, 2019
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4XPZ
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7ZVF
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![BU of 7zvf by Molmil](/molmil-images/mine/7zvf) | Crystal structure of human cathepsin L in complex with covalently bound CLIK148 | 分子名称: | (2S)-N-[(2S)-1-(dimethylamino)-1-oxidanylidene-3-phenyl-propan-2-yl]-2-oxidanyl-N'-(2-pyridin-2-ylethyl)butanediamide, 1,2-ETHANEDIOL, Cathepsin L, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Tsuge, H, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-05-15 | 公開日 | 2023-11-29 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
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5J4O
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5JAN
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5JAT
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7SNO
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![BU of 7sno by Molmil](/molmil-images/mine/7sno) | Structure of Bacple_01701(H214N), a 6-O-galactose porphyran sulfatase | 分子名称: | 1,2-ETHANEDIOL, 6-O-sulfo-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-6-O-sulfo-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose, Arylsulfatase, ... | 著者 | Ulaganathan, T, Cygler, M. | 登録日 | 2021-10-28 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations Biorxiv, 2023
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8IWW
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![BU of 8iww by Molmil](/molmil-images/mine/8iww) | hSPCA1 in the CaE1P-ADP state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ... | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | 登録日 | 2023-03-31 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8IWU
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![BU of 8iwu by Molmil](/molmil-images/mine/8iwu) | hSPCA1 in the E2~P state | 分子名称: | Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION, TETRAFLUOROALUMINATE ION | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | 登録日 | 2023-03-31 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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7SNJ
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![BU of 7snj by Molmil](/molmil-images/mine/7snj) | Structure of Bacple_01701, a 6-O-galactose porphyran sulfatase | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Arylsulfatase, ... | 著者 | Ulaganathan, T, Cygler, M. | 登録日 | 2021-10-28 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations Biorxiv, 2023
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5JE2
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![BU of 5je2 by Molmil](/molmil-images/mine/5je2) | Crystal structure of Burkholderia glumae ToxA Y7F mutant with bound S-adenosylhomocysteine (SAH) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, Methyl transferase, ... | 著者 | Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E. | 登録日 | 2016-04-17 | 公開日 | 2016-05-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.519 Å) | 主引用文献 | Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis. Biochemistry, 55, 2016
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4QJ5
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![BU of 4qj5 by Molmil](/molmil-images/mine/4qj5) | Structure of a fragment of human phospholipase C-beta3 delta472-581, bound to IP3 and in complex with Galphaq | 分子名称: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | 著者 | Lyon, A.M, Tesmer, J.J.G. | 登録日 | 2014-06-03 | 公開日 | 2014-10-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | 主引用文献 | Molecular mechanisms of phospholipase C beta 3 autoinhibition. Structure, 22, 2014
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4XYZ
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![BU of 4xyz by Molmil](/molmil-images/mine/4xyz) | Crystal structure of K33 linked di-Ubiquitin | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, IODIDE ION, ... | 著者 | Kristariyanto, Y.A, Abdul Rehman, S.A, Choi, S.Y, Ritorto, S, Campbell, D.G, Morrice, N.A, Toth, R, Kulathu, Y. | 登録日 | 2015-02-03 | 公開日 | 2015-03-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations. Biochem.J., 467, 2015
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6UXR
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![BU of 6uxr by Molmil](/molmil-images/mine/6uxr) | Crystal structure of BAK core domain BH3-groove-dimer in complex with LysoPC | 分子名称: | Bcl-2 homologous antagonist/killer, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | 著者 | Cowan, A.D, Colman, P.M, Czabotar, P.E. | 登録日 | 2019-11-07 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | BAK core dimers bind lipids and can be bridged by them. Nat.Struct.Mol.Biol., 27, 2020
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6YQG
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![BU of 6yqg by Molmil](/molmil-images/mine/6yqg) | Crystal structure of native Phycocyanin in spacegroup P63 at 1.45 Angstroms. | 分子名称: | C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN, ... | 著者 | Feiler, C.G, Falke, S, Sarrou, I. | 登録日 | 2020-04-17 | 公開日 | 2021-01-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | C-phycocyanin as a highly attractive model system in protein crystallography: unique crystallization properties and packing-diversity screening. Acta Crystallogr D Struct Biol, 77, 2021
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4QL0
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![BU of 4ql0 by Molmil](/molmil-images/mine/4ql0) | Crystal Structure Analysis of the Membrane Transporter FhaC (double mutant V169T, I176N) | 分子名称: | DI(HYDROXYETHYL)ETHER, Filamentous hemagglutinin transporter protein FhaC, HEXAETHYLENE GLYCOL, ... | 著者 | Maier, T, Clantin, B, Gruss, F, Dewitte, F, Delattre, A.S, Jacob-Dubuisson, F, Hiller, S, Villeret, V. | 登録日 | 2014-06-10 | 公開日 | 2015-06-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Conserved Omp85 lid-lock structure and substrate recognition in FhaC Nat Commun, 6, 2015
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5JMR
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6V1Y
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![BU of 6v1y by Molmil](/molmil-images/mine/6v1y) | Cryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Octamer | 分子名称: | (2S)-1-(nonanoyloxy)-3-(phosphonooxy)propan-2-yl tetradecanoate, (3beta,5beta,14beta,17alpha)-cholestan-3-ol, Potassium channel KAT1 | 著者 | Clark, M.D, Contreras, G.F, Shen, R, Perozo, E. | 登録日 | 2019-11-21 | 公開日 | 2020-06-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Electromechanical coupling in the hyperpolarization-activated K + channel KAT1. Nature, 583, 2020
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6YR4
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![BU of 6yr4 by Molmil](/molmil-images/mine/6yr4) | Dye-type peroxidase DtpB in the ferryl state: Spectroscopically Validated composite structure | 分子名称: | MAGNESIUM ION, OXYGEN ATOM, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Lucic, M, Dworkowski, F.S.N, Worrall, J.A.R, Hough, M.A. | 登録日 | 2020-04-19 | 公開日 | 2021-01-13 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Serial Femtosecond Zero Dose Crystallography Captures a Water-Free Distal Heme Site in a Dye-Decolorising Peroxidase to Reveal a Catalytic Role for an Arginine in Fe IV =O Formation. Angew.Chem.Int.Ed.Engl., 59, 2020
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5QCD
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![BU of 5qcd by Molmil](/molmil-images/mine/5qcd) | Crystal structure of human Cathepsin-S with bound ligand | 分子名称: | Cathepsin S, SULFATE ION, {(3S)-7-[(2-chloro-5-{5-(methylsulfonyl)-1-[3-(morpholin-4-yl)propyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}phenyl)ethynyl]-1,2,3,4-tetrahydroisoquinolin-3-yl}(piperidin-1-yl)methanone | 著者 | Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. | 登録日 | 2017-08-04 | 公開日 | 2017-12-20 | 最終更新日 | 2021-11-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of human Cathepsin-S with bound ligand To be published
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6VAJ
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![BU of 6vaj by Molmil](/molmil-images/mine/6vaj) | Crystal Structure Analysis of human PIN1 | 分子名称: | 2-chloro-N-(2,2-dimethylpropyl)-N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]acetamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, ... | 著者 | Seo, H.-S, Dhe-Paganon, S. | 登録日 | 2019-12-17 | 公開日 | 2020-12-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nat.Chem.Biol., 17, 2021
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5J8N
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6YE7
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![BU of 6ye7 by Molmil](/molmil-images/mine/6ye7) | E.coli's Putrescine receptor PotF complexed with Cadaverine | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, ... | 著者 | Shanmugaratnam, S, Kroeger, P, Hocker, B. | 登録日 | 2020-03-24 | 公開日 | 2021-01-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A comprehensive binding study illustrates ligand recognition in the periplasmic binding protein PotF. Structure, 29, 2021
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4QDF
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![BU of 4qdf by Molmil](/molmil-images/mine/4qdf) | Crystal structure of apo KshA5 and KshA1 in complex with 1,4-30Q-CoA from R. rhodochrous | 分子名称: | 3-ketosteroid 9alpha-hydroxylase oxygenase, FE (II) ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Penfield, J, Worrall, L.J, Strynadka, N.C, Eltis, L.D. | 登録日 | 2014-05-13 | 公開日 | 2014-07-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Substrate specificities and conformational flexibility of 3-ketosteroid 9 alpha-hydroxylases. J.Biol.Chem., 289, 2014
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5J56
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![BU of 5j56 by Molmil](/molmil-images/mine/5j56) | RTA-V1C7 | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | 著者 | Rudolph, M.J. | 登録日 | 2016-04-01 | 公開日 | 2016-12-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit. J. Biol. Chem., 292, 2017
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