5J3N
| C-terminal domain of EcoR124I HsdR subunit fused with the pH-sensitive GFP variant ratiometric pHluorin | 分子名称: | Green fluorescent protein,HsdR | 著者 | Grinkevich, P, Iermak, I, Luedtke, N, Mesters, J.R, Ettrich, R, Ludwig, J. | 登録日 | 2016-03-31 | 公開日 | 2017-04-12 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structure of a novel domain of the motor subunit of the Type I restriction enzyme EcoR124 involved in complex assembly and DNA binding. J. Biol. Chem., 293, 2018
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4Q9Q
| Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab | 分子名称: | (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | 著者 | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | 登録日 | 2014-05-01 | 公開日 | 2014-06-18 | 最終更新日 | 2017-07-26 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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8W2L
| TRPM7 structure in complex with anticancer agent CCT128930 in closed state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium, ... | 著者 | Nadezhdin, K.D, Sobolevsky, A.I. | 登録日 | 2024-02-20 | 公開日 | 2024-04-17 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930. Cell Rep, 43, 2024
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5XV6
| Crystal structure of ATG101-ATG13HORMA | 分子名称: | Autophagy-related protein 101, Autophagy-related protein 13 | 著者 | Kim, B.-W, Song, H.K. | 登録日 | 2017-06-26 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.455 Å) | 主引用文献 | The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation. Autophagy, 14, 2018
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4KW8
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8A98
| CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT | 分子名称: | 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... | 著者 | Rajan, K.S, Yonath, A, Bashan, A. | 登録日 | 2022-06-28 | 公開日 | 2023-10-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.46 Å) | 主引用文献 | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
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8CIV
| Translocation intermediate 5 (TI-5) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | 登録日 | 2023-02-10 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.47 Å) | 主引用文献 | mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
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8OVA
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6GEZ
| THE STRUCTURE OF TWITCH-2B N532F | 分子名称: | CALCIUM ION, FORMIC ACID, Green fluorescent protein,Optimized Ratiometric Calcium Sensor,Green fluorescent protein,Green fluorescent protein | 著者 | Trigo Mourino, P, Paulat, M, Thestrup, T, Griesbeck, O, Griesinger, C, Becker, S. | 登録日 | 2018-04-27 | 公開日 | 2019-08-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Dynamic tuning of FRET in a green fluorescent protein biosensor. Sci Adv, 5, 2019
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4D2C
| Structure of a di peptide bound POT family peptide transporter | 分子名称: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ... | 著者 | Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S. | 登録日 | 2014-05-09 | 公開日 | 2014-06-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters. Embo Rep., 15, 2014
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6S67
| Structure of the Fluorescent Protein AausFP1 from Aequorea cf. australis at pH 7.0 | 分子名称: | Aequorea cf. australis fluorescent protein 1 (AausFP1), GLYCEROL | 著者 | Depernet, H, Gotthard, G, Lambert, G.G, Shaner, N.C, Royant, A. | 登録日 | 2019-07-02 | 公開日 | 2020-07-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Aequorea's secrets revealed: New fluorescent proteins with unique properties for bioimaging and biosensing. Plos Biol., 18, 2020
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2RH5
| Structure of Apo Adenylate Kinase from Aquifex Aeolicus | 分子名称: | Adenylate kinase | 著者 | Thai, V, Wolf-Watz, M, Fenn, T, Pozharski, E, Wilson, M.A, Petsko, G.A, Kern, D. | 登録日 | 2007-10-05 | 公開日 | 2007-12-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Intrinsic motions along an enzymatic reaction trajectory. Nature, 450, 2007
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7WVI
| Crystal structure of SIA28 | 分子名称: | Heavy chain of SIA28, Light chain of SIA28 | 著者 | Chen, Y, Qi, J, Gao, G.F. | 登録日 | 2022-02-10 | 公開日 | 2023-01-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
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7JRN
| Crystal structure of the wild type SARS-CoV-2 papain-like protease (PLPro) with inhibitor GRL0617 | 分子名称: | 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, SULFATE ION, ... | 著者 | Sacco, M, Ma, C, Wang, J, Chen, Y. | 登録日 | 2020-08-12 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay. Acs Cent.Sci., 7, 2021
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6SVM
| Crystal structure of human GFAT-1 in complex with Glucose-6-Phosphate, L-Glu, and UDP-GalNAc | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1, ... | 著者 | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | 登録日 | 2019-09-18 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.481 Å) | 主引用文献 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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6WV7
| Human VKOR with Chlorophacinone | 分子名称: | Chlorophacinone, Vitamin K epoxide reductase, termini restrained by green fluorescent protein | 著者 | Liu, S, Sukumar, N, Li, W. | 登録日 | 2020-05-05 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.483 Å) | 主引用文献 | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
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8TEE
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5HZO
| GFP mutant S205G | 分子名称: | D-MALATE, Green fluorescent protein, UNDECYL-MALTOSIDE | 著者 | Remington, S.J, Trujillo, K. | 登録日 | 2016-02-02 | 公開日 | 2016-02-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Ultrafast Dynamics and Mechanisms of Proton Transfer in the GFP S205G Mutant To Be Published
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7S3F
| Structure of cofactor pyridoxal 5-phosphate bound human ornithine decarboxylase in complex with its inhibitor 1-amino-oxy-3-aminopropane | 分子名称: | 3-AMINOOXY-1-AMINOPROPANE, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Zhou, X.E, Suino-Powell, K, Schultz, C.R, Aleiwi, B, Brunzelle, J.S, Lamp, J, Vega, I.E, Ellsworth, E, Bachmann, A.S, Melcher, K. | 登録日 | 2021-09-06 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane. Biochem.J., 478, 2021
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3WLC
| Crystal structure of dimeric GCaMP6m | 分子名称: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | 著者 | Ding, J, Luo, A.F, Hu, L.Y, Wang, D.C, Shao, F. | 登録日 | 2013-11-08 | 公開日 | 2014-01-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structural basis of the ultrasensitive calcium indicator GCaMP6. Sci China Life Sci, 57, 2014
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4W6C
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6F64
| Crystal structure of the SYCP1 C-terminal back-to-back assembly | 分子名称: | ACETATE ION, Synaptonemal complex protein 1 | 著者 | Dunce, J.M, Millan, C, Uson, I, Davies, O.R. | 登録日 | 2017-12-04 | 公開日 | 2018-06-06 | 最終更新日 | 2020-04-22 | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | 主引用文献 | Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly. Nat. Struct. Mol. Biol., 25, 2018
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4BD6
| Bax domain swapped dimer in complex with BaxBH3 | 分子名称: | APOPTOSIS REGULATOR BAX | 著者 | Czabotar, P.E, Westphal, D, Adams, J.M, Colman, P.M. | 登録日 | 2012-10-05 | 公開日 | 2013-02-13 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | 主引用文献 | Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis. Cell(Cambridge,Mass.), 152, 2013
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6LEL
| Structure of E. coli beta-glucuronidase complex with C6-hexyl uronic isofagomine | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-2-hexyl-4,5-bis(oxidanyl)piperidine-3-carboxylic acid, Beta-D-glucuronidase | 著者 | Lin, H.-Y, Kuo, Y.-H, Lin, C.-H. | 登録日 | 2019-11-25 | 公開日 | 2021-01-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | 主引用文献 | Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity. Commun Biol, 4, 2021
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7BYL
| Cryo-EM structure of human KCNQ4 | 分子名称: | Calmodulin-3, Green fluorescent protein,Potassium voltage-gated channel subfamily KQT member 4, POTASSIUM ION, ... | 著者 | Shen, H, Li, T, Yue, Z. | 登録日 | 2020-04-23 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs. Mol.Cell, 81, 2021
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