6RQC
 
 | | Cryo-EM structure of an MCM loading intermediate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (88-MER), ... | | 著者 | Miller, T.C.R, Locke, J, Costa, A. | | 登録日 | 2019-05-15 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM.
Nature, 575, 2019
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5J6G
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6OJP
 | | Structure of glycolipid alpha-GSA[8,6P] in complex with mouse CD1d | | 分子名称: | (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(6-phenylhexyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Zajonc, D.M, Bitra, A. | | 登録日 | 2019-04-11 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
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6Z4M
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7LCY
 | | Crystal structure of the ligand-free ARM domain from Drosophila SARM1 | | 分子名称: | Isoform B of NAD(+) hydrolase sarm1 | | 著者 | Gu, W, Nanson, J.D, Luo, Z, McGuinness, H.Y, Manik, M.K, Jia, X, Ve, T, Kobe, B. | | 登録日 | 2021-01-12 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-04-21 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021
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7LCZ
 | | Crystal structure of the ARM domain from Drosophila SARM1 in complex with NMN | | 分子名称: | 1,2-ETHANEDIOL, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Isoform B of NAD(+) hydrolase sarm1, ... | | 著者 | Gu, W, Nanson, J.D, Luo, Z, Jia, X, Manik, M.K, Ve, T, Kobe, B. | | 登録日 | 2021-01-12 | | 公開日 | 2021-03-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021
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2WYT
 | | 1.0 A resolution structure of L38V SOD1 mutant | | 分子名称: | ACETATE ION, CHLORIDE ION, COPPER (II) ION, ... | | 著者 | Antonyuk, S.V, Strange, R.W, Hasnain, S.S. | | 登録日 | 2009-11-20 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Structural Discovery of Small Molecule Binding Sites in Cu-Zn Human Superoxide Dismutase Familial Amyotrophic Lateral Sclerosis Mutants Provides Insights for Lead Optimization.
J.Med.Chem., 53, 2010
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6OPD
 | | Crystal Structure of ILNAMIVKI peptide bound to HLA-A2 | | 分子名称: | ACETATE ION, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Davancaze, L.M, Arbuiso, A, Baker, B.M. | | 登録日 | 2019-04-24 | | 公開日 | 2019-09-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.791 Å) | | 主引用文献 | Structure Based Prediction of Neoantigen Immunogenicity.
Front Immunol, 10, 2019
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6OB0
 | | Compound 2 bound structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in HEK293-F cells | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Arora, R, Horton, P.A, Benson, T.E, Romanowski, M.J. | | 登録日 | 2019-03-19 | | 公開日 | 2019-05-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Structure of lipoprotein lipase in complex with GPIHBP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
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1CRP
 | | THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY | | 分子名称: | C-H-RAS P21 PROTEIN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Kraulis, P.J, Domaille, P.J, Campbell-Burk, S.L, Van Aken, T, Laue, E.D. | | 登録日 | 1993-11-24 | | 公開日 | 1994-07-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy.
Biochemistry, 33, 1994
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1D2B
 | | THE MMP-INHIBITORY, N-TERMINAL DOMAIN OF HUMAN TISSUE INHIBITOR OF METALLOPROTEINASES-1 (N-TIMP-1), SOLUTION NMR, 29 STRUCTURES | | 分子名称: | Metalloproteinase inhibitor 1 | | 著者 | Wu, B, Arumugam, S, Semenchenko, V, Brew, K, Van Doren, S.R. | | 登録日 | 1999-09-22 | | 公開日 | 1999-12-22 | | 最終更新日 | 2022-03-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of tissue inhibitor of metalloproteinases-1 implicates localized induced fit in recognition of matrix metalloproteinases.
J.Mol.Biol., 295, 2000
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1CRR
 | | THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY | | 分子名称: | C-H-RAS P21 PROTEIN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Kraulis, P.J, Domaille, P.J, Campbell-Burk, S.L, Van Aken, T, Laue, E.D. | | 登録日 | 1993-11-24 | | 公開日 | 1994-07-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy.
Biochemistry, 33, 1994
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6OAU
 | | Apo Structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in GnTI-deficient HEK293-F cells | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, ... | | 著者 | Arora, R, Horton, P.A, Benson, T.E, Romanowski, M.J. | | 登録日 | 2019-03-18 | | 公開日 | 2019-05-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structure of lipoprotein lipase in complex with GPIHBP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
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1D8B
 | | NMR STRUCTURE OF THE HRDC DOMAIN FROM SACCHAROMYCES CEREVISIAE RECQ HELICASE | | 分子名称: | SGS1 RECQ HELICASE | | 著者 | Liu, Z, Macias, M.J, Bottomley, M.J, Stier, G, Linge, J.P, Nilges, M, Bork, P, Sattler, M. | | 登録日 | 1999-10-21 | | 公開日 | 2000-01-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins.
Structure Fold.Des., 7, 1999
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5IWP
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of calcium | | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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1CRB
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1CTI
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1CTU
 | | TRANSITION-STATE SELECTIVITY FOR A SINGLE OH GROUP DURING CATALYSIS BY CYTIDINE DEAMINASE | | 分子名称: | 4-HYDROXY-3,4-DIHYDRO-ZEBULARINE, CYTIDINE DEAMINASE, ZINC ION | | 著者 | Xiang, S, Short, S.A, Wolfenden, R, Carter, C.W. | | 登録日 | 1995-02-11 | | 公開日 | 1995-05-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Transition-state selectivity for a single hydroxyl group during catalysis by cytidine deaminase.
Biochemistry, 34, 1995
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1CVA
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2VR6
 | | Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.3 A resolution | | 分子名称: | COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ... | | 著者 | Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J. | | 登録日 | 2008-03-28 | | 公開日 | 2008-04-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
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1CQH
 | | HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN REF-1 (RESIDUES 59-71 OF THE P50 SUBUNIT OF NFKB), NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | REF-1 PEPTIDE, THIOREDOXIN | | 著者 | Clore, G.M, Qin, J, Gronenborn, A.M. | | 登録日 | 1996-04-02 | | 公開日 | 1996-08-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Structure, 4, 1996
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7LII
 | | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant S7D | | 分子名称: | Maritimacin, RIBOFLAVIN | | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | | 登録日 | 2021-01-27 | | 公開日 | 2022-02-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages.
Sci Adv, 8, 2022
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1CN7
 | | Yeast ribosomal protein L30 | | 分子名称: | 60S RIBOSOMAL PROTEIN L30E | | 著者 | Mao, H, Willamson, J.R. | | 登録日 | 1999-05-26 | | 公開日 | 1999-10-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Local folding coupled to RNA binding in the yeast ribosomal protein L30.
J.Mol.Biol., 292, 1999
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1D8V
 | | THE RESTRAINED AND MINIMIZED AVERAGE NMR STRUCTURE OF MAP30. | | 分子名称: | ANTI-HIV AND ANTI-TUMOR PROTEIN MAP30 | | 著者 | Wang, Y.-X, Neamati, N, Jacob, J, Palmer, I, Stahl, S.J. | | 登録日 | 1999-10-26 | | 公開日 | 1999-11-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of anti-HIV-1 and anti-tumor protein MAP30: structural insights into its multiple functions.
Cell(Cambridge,Mass.), 99, 1999
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6Z4H
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