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6QMG
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Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 5-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid at 1.8A resolution.
分子名称: INDOLYLPROPIONIC ACID, Phosphopantetheine adenylyltransferase
著者Blaszczyk, M, Blundell, T.L.
登録日2019-02-07
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Fragment linking applied to the discovery of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase inhibitors
To Be Published
5E3Q
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BU of 5e3q by Molmil
Crystal structure of DapD in complex with succinyl-CoA from Corynebacterium glutamicum
分子名称: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, SUCCINYL-COENZYME A
著者Sagong, H.-Y, Kim, K.-J.
登録日2015-10-03
公開日2015-11-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure and Biochemical Characterization of Tetrahydrodipicolinate N-Succinyltransferase from Corynebacterium glutamicum.
J.Agric.Food Chem., 63, 2015
5GCN
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CATALYTIC DOMAIN OF TETRAHYMENA GCN5 HISTONE ACETYLTRANSFERASE IN COMPLEX WITH COENZYME A
分子名称: COENZYME A, HISTONE ACETYLTRANSFERASE GCN5
著者Lin, Y, Fletcher, C.M, Zhou, J, Allis, C.D, Wagner, G.
登録日1999-03-24
公開日1999-07-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the catalytic domain of GCN5 histone acetyltransferase bound to coenzyme A
Nature, 400, 1999
5E3R
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BU of 5e3r by Molmil
Crystal structure of DapD in complex with 2-aminopimelate from Corynebacterium glutamicum
分子名称: (2S)-2-aminoheptanedioic acid, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
著者Sagong, H.-Y, Kim, K.-J.
登録日2015-10-03
公開日2015-11-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure and Biochemical Characterization of Tetrahydrodipicolinate N-Succinyltransferase from Corynebacterium glutamicum.
J.Agric.Food Chem., 63, 2015
7XSN
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BU of 7xsn by Molmil
Native Tetrahymena ribozyme conformation
分子名称: RNA (387-MER)
著者Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R.
登録日2022-05-14
公開日2022-08-03
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
5TCX
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BU of 5tcx by Molmil
Crystal structure of human tetraspanin CD81
分子名称: CD81 antigen, CHOLESTEROL
著者Zimmerman, B, McMillan, B.J, Seegar, T.C.M, Kruse, A.C, Blacklow, S.C.
登録日2016-09-16
公開日2016-11-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.955 Å)
主引用文献Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket.
Cell, 167, 2016
4ERD
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BU of 4erd by Molmil
Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 in complex with stem IV of telomerase RNA
分子名称: 5'-R(P*GP*GP*UP*CP*GP*AP*CP*AP*UP*CP*UP*UP*CP*GP*GP*AP*UP*GP*GP*AP*CP*C)-3', POTASSIUM ION, Telomerase associated protein p65
著者Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J.
登録日2012-04-19
公開日2012-06-20
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.589 Å)
主引用文献Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
4NTN
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BU of 4ntn by Molmil
E.coli QueD, SeMet protein, 2A resolution
分子名称: 6-carboxy-5,6,7,8-tetrahydropterin synthase, FORMIC ACID, ZINC ION
著者Bandarian, V, Roberts, S.A, Miles, Z.D.
登録日2013-12-02
公開日2014-07-16
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.
J.Biol.Chem., 289, 2014
4NTK
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BU of 4ntk by Molmil
QueD from E. coli
分子名称: 2-amino-6-[(1Z)-1,2-dihydroxyprop-1-en-1-yl]-7,8-dihydropteridin-4(3H)-one, 6-carboxy-5,6,7,8-tetrahydropterin synthase, ACETATE ION, ...
著者Bandarian, V, Roberts, S.A, Miles, Z.D.
登録日2013-12-02
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.
J.Biol.Chem., 289, 2014
3MA5
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BU of 3ma5 by Molmil
Crystal structure of the tetratricopeptide repeat domain protein Q2S6C5_SALRD from Salinibacter ruber. Northeast Structural Genomics Consortium Target SrR115c.
分子名称: Tetratricopeptide repeat domain protein
著者Vorobiev, S, Neely, H, Seetharaman, J, Wang, H, Foote, E.L, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2010-03-23
公開日2010-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the tetratricopeptide repeat domain protein Q2S6C5_SALRD from Salinibacter ruber.
To be Published
3HVL
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BU of 3hvl by Molmil
Tethered PXR-LBD/SRC-1p complexed with SR-12813
分子名称: Pregnane X receptor, Linker, Steroid receptor coactivator 1, ...
著者Lesburg, C.A, Wang, W, Prosise, W.W, Chen, J, Taremi, S.S, Le, H.V, Madison, V, Cui, X, Thomas, A, Cheng, K.C.
登録日2009-06-16
公開日2009-08-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability
Protein Eng.Des.Sel., 21, 2008
3O5N
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BU of 3o5n by Molmil
Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders
分子名称: (3aS,4R,9bR)-9-nitro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4,6-dicarboxylic acid, SH3 and multiple ankyrin repeat domains protein 3
著者Saupe, J, Roske, Y, Schillinger, C, Kamdem, N, Radetzki, S, Diehl, A, Oschkinat, H, Krause, G, Heinemann, U, Rademann, J.
登録日2010-07-28
公開日2011-06-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the shank3 PDZ domain.
Chemmedchem, 6, 2011
7XSM
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BU of 7xsm by Molmil
Misfolded Tetrahymena ribozyme conformation 3
分子名称: RNA (388-MER)
著者Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R.
登録日2022-05-14
公開日2022-08-03
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.01 Å)
主引用文献Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
7XSL
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BU of 7xsl by Molmil
Misfolded Tetrahymena ribozyme conformation 2
分子名称: RNA (388-MER)
著者Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R.
登録日2022-05-14
公開日2022-08-03
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
7XSK
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BU of 7xsk by Molmil
Misfolded Tetrahymena ribozyme conformation 1
分子名称: RNA (388-MER)
著者Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R.
登録日2022-05-14
公開日2022-08-03
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
7A4G
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BU of 7a4g by Molmil
Aquifex aeolicus lumazine synthase-derived nucleocapsid variant NC-1 (180-mer)
分子名称: Antitermination protein N,6,7-dimethyl-8-ribityllumazine synthase,6,7-dimethyl-8-ribityllumazine synthase
著者Tetter, S, Hilvert, D.
登録日2020-08-19
公開日2021-06-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Evolution of a virus-like architecture and packaging mechanism in a repurposed bacterial protein.
Science, 372, 2021
4EYT
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BU of 4eyt by Molmil
Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65
分子名称: SULFATE ION, Telomerase associated protein p65
著者Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J.
登録日2012-05-01
公開日2012-06-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
6T14
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BU of 6t14 by Molmil
Native structure of mosquitocidal Cyt1A protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals at pH 7
分子名称: SODIUM ION, Type-1Aa cytolytic delta-endotoxin
著者Tetreau, G, Banneville, A.S, Andreeva, E, Brewster, A.S, Hunter, M.S, Sierra, R.G, Young, I.D, Boutet, S, Coquelle, N, Cascio, D, Sawaya, M.R, Sauter, N.K, Colletier, J.P.
登録日2019-10-03
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Nat Commun, 11, 2020
6T1C
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BU of 6t1c by Molmil
Structure of the C7S mutant of mosquitocidal Cyt1A protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals at pH 7
分子名称: SODIUM ION, Type-1Aa cytolytic delta-endotoxin
著者Tetreau, G, Banneville, A.S, Andreeva, E, Brewster, A.S, Hunter, M.S, Sierra, R.G, Young, I.D, Boutet, S, Coquelle, N, Cascio, D, Sawaya, M.R, Sauter, N.K, Colletier, J.P.
登録日2019-10-03
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Nat Commun, 11, 2020
4K2X
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OxyS anhydrotetracycline hydroxylase from Streptomyces rimosus
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Polyketide oxygenase/hydroxylase
著者Wang, P, Sawaya, M.R, Tang, Y.
登録日2013-04-09
公開日2013-05-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Uncovering the Enzymes that Catalyze the Final Steps in Oxytetracycline Biosynthesis.
J.Am.Chem.Soc., 135, 2013
6T1A
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BU of 6t1a by Molmil
Structure of mosquitocidal Cyt1Aa protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals at pH 10
分子名称: CALCIUM ION, Type-1Aa cytolytic delta-endotoxin
著者Tetreau, G, Banneville, A.S, Andreeva, E, Brewster, A.S, Hunter, M.S, Sierra, R.G, Young, I.D, Boutet, S, Coquelle, N, Cascio, D, Sawaya, M.R, Sauter, N.K, Colletier, J.P.
登録日2019-10-03
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Nat Commun, 11, 2020
6T19
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BU of 6t19 by Molmil
Structure of mosquitocidal Cyt1A protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals soaked with DTT at pH 7
分子名称: SODIUM ION, Type-1Aa cytolytic delta-endotoxin
著者Tetreau, G, Banneville, A.S, Andreeva, E, Brewster, A.S, Hunter, M.S, Sierra, R.G, Young, I.D, Boutet, S, Coquelle, N, Cascio, D, Sawaya, M.R, Sauter, N.K, Colletier, J.P.
登録日2019-10-03
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Nat Commun, 11, 2020
5CQW
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Tetragonal Complex Structure of Protein Kinase CK2 Catalytic Subunit with a Benzotriazole-Based Inhibitor Generated by click-chemistry
分子名称: 4-[4-[2-[4,5,6,7-tetrakis(bromanyl)benzotriazol-2-yl]ethyl]-1,2,3-triazol-1-yl]butan-1-amine, CHLORIDE ION, Casein kinase II subunit alpha, ...
著者Niefind, K, Schnitzler, A, Swider, R, Maslyk, M, Ramos, A.
登録日2015-07-22
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Synthesis, Biological Activity and Structural Study of New Benzotriazole-Based Protein Kinase CK2 Inhibitors
Rsc Adv, 5, 2015
8G2N
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BU of 8g2n by Molmil
Crystal structure of Tetrahymena thermophila G-rich DNA with novel ligand PyDH2
分子名称: 4,4'-{pyridine-2,6-diylbis[carbonyl-(1E)-hydrazin-2-yl-1-ylidene-(E)-methanylylidene]}bis(1-methylquinolin-1-ium), G-rich DNA, MAGNESIUM ION, ...
著者Martin, K.N, Yatsunyk, L.A.
登録日2023-02-06
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Crystal structure of Tetrahymena thermophila G-rich DNA with novel ligand PyDH2
To be published
5MGX
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The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP8, yeast HSP90 C-terminus
著者Roe, S.M, Blundell, K.L, Prodromou, C.
登録日2016-11-22
公開日2017-03-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90.
PLoS ONE, 12, 2017

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