5MGX

The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90

Summary for 5MGX

Entry DOI	10.2210/pdb5mgx/pdb
Descriptor	yeast HSP90 C-terminus, Peptidyl-prolyl cis-trans isomerase FKBP8 (3 entities in total)
Functional Keywords	hsp90, ppiase, teratricopeptide, immunophilin, isomerase
Biological source	Homo sapiens (Human) More
Cellular location	Mitochondrion . Isoform 1: Mitochondrion membrane ; Single-pass membrane protein; Cytoplasmic side . Isoform 3: Mitochondrion membrane ; Single-pass membrane protein; Cytoplasmic side : Q14318
Total number of polymer chains	8
Total formula weight	131086.60
Authors	Roe, S.M.,Blundell, K.L.,Prodromou, C. (deposition date: 2016-11-22, release date: 2017-03-22, Last modification date: 2024-01-17)
Primary citation	Blundell, K.L.,Pal, M.,Roe, S.M.,Pearl, L.H.,Prodromou, C. The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90. PLoS ONE, 12:e0173543-e0173543, 2017 Cited by PubMed: 28278223 DOI: 10.1371/journal.pone.0173543 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation