7NX7
| Crystal structure of the K417N mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CITRIC ACID, ... | 著者 | Zhou, D, Ren, J, Stuart, D. | 登録日 | 2021-03-17 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Antibody evasion by the P.1 strain of SARS-CoV-2. Cell, 184, 2021
|
|
7NXB
| Crystal structure of the receptor binding domain of SARS-CoV-2 P.1 variant Spike glycoprotein in complex with COVOX-222 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-222 Fab heavy chain, COVOX-222 Fab light chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D. | 登録日 | 2021-03-17 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Antibody evasion by the P.1 strain of SARS-CoV-2. Cell, 184, 2021
|
|
7NX8
| Crystal structure of the K417T mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CITRIC ACID, ... | 著者 | Zhou, D, Ren, J, Stuart, D. | 登録日 | 2021-03-17 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Antibody evasion by the P.1 strain of SARS-CoV-2. Cell, 184, 2021
|
|
7NX9
| Crystal structure of the N501Y mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, COVOX-222 Fab heavy chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D. | 登録日 | 2021-03-17 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Antibody evasion by the P.1 strain of SARS-CoV-2. Cell, 184, 2021
|
|
7NT9
| Trimeric SARS-CoV-2 spike ectodomain in complex with biliverdin (closed conformation) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | 著者 | Rosa, A, Pye, V.E, Nans, A, Cherepanov, P. | 登録日 | 2021-03-09 | 公開日 | 2021-04-28 | 最終更新日 | 2021-06-09 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity. Sci Adv, 7, 2021
|
|
7NTA
| Trimeric SARS-CoV-2 spike ectodomain in complex with biliverdin (one RBD erect) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | 著者 | Rosa, A, Pye, V.E, Nans, A, Cherepanov, P. | 登録日 | 2021-03-09 | 公開日 | 2021-04-28 | 最終更新日 | 2021-06-09 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity. Sci Adv, 7, 2021
|
|
7NTC
| Trimeric SARS-CoV-2 spike ectodomain bound to P008_056 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | 著者 | Rosa, A, Pye, V.E, Nans, A, Cherepanov, P. | 登録日 | 2021-03-09 | 公開日 | 2021-04-28 | 最終更新日 | 2021-06-09 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity. Sci Adv, 7, 2021
|
|
7MW2
| |
7MW3
| |
7MW5
| |
7BNO
| Open conformation of D614G SARS-CoV-2 spike with 2 Erect RBDs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Benton, D.J, Wrobel, A.G, Rosenthal, P.B, Gamblin, S.J. | 登録日 | 2021-01-22 | 公開日 | 2021-02-03 | 最終更新日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | The effect of the D614G substitution on the structure of the spike glycoprotein of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7BWJ
| crystal structure of SARS-CoV-2 antibody with RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... | 著者 | Wang, X, Ge, J. | 登録日 | 2020-04-14 | 公開日 | 2020-06-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Human neutralizing antibodies elicited by SARS-CoV-2 infection. Nature, 584, 2020
|
|
7BNM
| Closed conformation of D614G SARS-CoV-2 spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Benton, D.J, Wrobel, A.G, Rosenthal, P.B, Gamblin, S.J. | 登録日 | 2021-01-22 | 公開日 | 2021-02-03 | 最終更新日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The effect of the D614G substitution on the structure of the spike glycoprotein of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7BYR
| BD23-Fab in complex with the S ectodomain trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab23-Fab-Heavy Chain, ... | 著者 | Zhu, Q, Wang, G, Xiao, J. | 登録日 | 2020-04-24 | 公開日 | 2020-06-10 | 最終更新日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | 主引用文献 | Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells. Cell, 182, 2020
|
|
7CWO
| SARS-CoV-2 spike protein RBD and P17 fab complex | 分子名称: | Spike glycoprotein, heavy chain of P17 Fab, light chain of P17 Fab | 著者 | Wang, X, Wang, N. | 登録日 | 2020-08-29 | 公開日 | 2020-12-16 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection. Cell Res., 31, 2021
|
|
7CHF
| |
7CJF
| Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... | 著者 | Guo, Y, Li, X, Zhang, G, Fu, D, Schweizer, L, Zhang, H, Rao, Z. | 登録日 | 2020-07-10 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.108 Å) | 主引用文献 | A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. Nat Commun, 12, 2021
|
|
7C8V
| Structure of sybody SR4 in complex with the SARS-CoV-2 S Receptor Binding domain (RBD) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ... | 著者 | Li, T, Yao, H, Cai, H, Qin, W, Li, D. | 登録日 | 2020-06-03 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection. Nat Commun, 12, 2021
|
|
7CAI
| SARS-CoV-2 S trimer with two RBDs in the open state and complexed with two H014 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H014 Fab, ... | 著者 | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Wang, Y, Rao, Z, Qin, C, Wang, X. | 登録日 | 2020-06-08 | 公開日 | 2020-09-23 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. Science, 369, 2020
|
|
7CHH
| Cryo-EM structure of the SARS-CoV-2 S-6P in complex with BD-368-2 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BD-368-2 Fab heavy chain, ... | 著者 | Xiao, J, Zhu, Q, Wang, G. | 登録日 | 2020-07-05 | 公開日 | 2020-09-16 | 最終更新日 | 2020-11-25 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy. Cell, 183, 2020
|
|
7C8W
| Structure of sybody MR17 in complex with the SARS-CoV-2 S receptor-binding domain (RBD) | 分子名称: | GLYCEROL, Spike protein S1, Synthetic nanobody MR17, ... | 著者 | Li, T, Cai, H, Yao, H, Qin, W, Li, D. | 登録日 | 2020-06-03 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection. Nat Commun, 12, 2021
|
|
7CDI
| Crystal structure of SARS-CoV-2 antibody P2C-1F11 with RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P2C-1F11 heavy chain, ... | 著者 | Wang, X, Zhang, L, Ge, J, Wang, R. | 登録日 | 2020-06-19 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry. Nat Commun, 12, 2021
|
|
7CDJ
| Crystal structure of SARS-CoV-2 antibody P2C-1A3 with RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P2C-1A3 heavy chain, ... | 著者 | Wang, X, Zhang, L, Ge, J, Wang, R. | 登録日 | 2020-06-19 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.396 Å) | 主引用文献 | Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry. Nat Commun, 12, 2021
|
|
7CHE
| |
7CAH
| The interface of H014 Fab binds to SARS-CoV-2 S | 分子名称: | Heavy chain of H014 Fab, Light chain of H014 Fab, Spike protein S1 | 著者 | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Rao, Z, wang, Y, Qin, C, Wang, X. | 登録日 | 2020-06-08 | 公開日 | 2020-08-12 | 最終更新日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. Science, 369, 2020
|
|