PDB: 226262 件ウェブページステータス検索Chemie searchBIRD

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4UVB	LSD1(KDM1A)-CoREST in complex with 1-Methyl-Tranylcypromine (1S,2R) 分子名称: LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(1R,3S,3aS,7aS)-1-amino-1,10,11-trimethyl-4,6-dioxo-3-phenyl-2,3,5,6,7,7a-hexahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate 著者 Vianello, P, Botrugno, O, Cappa, A, Ciossani, G, Dessanti, P, Mai, A, Mattevi, A, Meroni, G, Minucci, S, Thaler, F, Tortorici, M, Trifiro, P, Valente, S, Villa, M, Varasi, M, Mercurio, C. 登録日 2014-08-05 公開日 2014-09-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Synthesis, Biological Activity and Mechanistic Insights of 1-Substituted Cyclopropylamine Derivatives: A Novel Class of Irreversible Inhibitors of Histone Demethylase Kdm1A. Eur.J.Med.Chem., 86C, 2014
2RP1	Refined solution structure of the PEMV-1 mRNA pseudoknot, regularized average structure 分子名称: PEMV-1 mRNA pseudoknot 著者 Cornish, P.V, Hennig, M, Giedroc, D.P. 登録日 2008-04-25 公開日 2009-03-31 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Frameshifting RNA pseudoknots: Structure and mechanism. Virus Res., 139, 2009
8HHI	Crystal structure of a triple-helix region of human collagen type III 分子名称: human collagen type III 著者 Yan, Z.C, Zhang, D, Qin, B. 登録日 2022-11-16 公開日 2023-01-18 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of a triple-helix region of human collagen type III To Be Published
5SR1	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z1272415642 - (R) isomer 分子名称: (3R)-3-[(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-1lambda~6~-thiane-1,1-dione, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
8H0S	Crystal structure of MnmM from B. subtilis complexed with Gln-TTG anti-codon stem loop and SAM (2.90 A) 分子名称: Putative rRNA methylase YtqB, RNA (5'-R(*AP*CP*GP*GP*AP*CP*UP*UP*UP*GP*AP*CP*UP*CP*CP*GP*U)-3'), S-ADENOSYLMETHIONINE 著者 Kim, J, Lee, J, Cho, G. 登録日 2022-09-30 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification. Nucleic Acids Res., 51, 2023
2RP5	Solution structure of the oligomerization domain in CEP-1 分子名称: Putative uncharacterized protein cep-1 著者 Ou, H.D, Doetsch, V. 登録日 2008-05-01 公開日 2008-05-27 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural evolution of C-terminal domains in the p53 family Embo J., 26, 2007
4UWD	HIF prolyl hydroxylase 2 (PHD2/ EGLN1) D315E VARIANT in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9) 分子名称: EGL NINE HOMOLOG 1, MANGANESE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE 著者 Chowdhury, R, Tarhonskaya, H, Schofield, C.J. 登録日 2014-08-11 公開日 2014-08-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.721 Å) 主引用文献 Investigating the Contribution of the Active Site Environment to the Slow Reaction of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain 2 with Oxygen. Biochem.J., 463, 2014
8H0T	Crystal structure of MnmM from B. subtilis complexed with SAH (1.17 A) 分子名称: Putative rRNA methylase YtqB, S-ADENOSYL-L-HOMOCYSTEINE 著者 Kim, J, Lee, J, Cho, G. 登録日 2022-09-30 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification. Nucleic Acids Res., 51, 2023
5SOO	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000897286891 - (R) isomer 分子名称: 4-{(3R)-3-[(1,3-thiazol-2-yl)methyl]pyrrolidin-1-yl}-7H-pyrrolo[2,3-d]pyrimidine, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
4URS	Crystal Structure of GGDEF domain from T.maritima 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DIGUANYLATE CYCLASE, ... 著者 Deepthi, A, Liew, C.W, Liang, Z.X, Swaminathan, K, Lescar, J. 登録日 2014-07-02 公開日 2014-10-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability Plos One, 9, 2014
2RQH	Structure of GSPT1/ERF3A-PABC 分子名称: G1 to S phase transition 1, Polyadenylate-binding protein 1 著者 Osawa, M, Nakanishi, T, Hosoda, N, Uchida, S, Hoshino, T, Katada, I, Shimada, I. 登録日 2009-05-08 公開日 2010-05-26 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Eukaryotic Translation Termination Factor Gspt/Erf3 Recognizes Pabp with Chemical Exchange Using Two Overlapping Motifs To be Published
8HFS	The structure of LcnA, LciA, and the man-PTS of Lactococcus lactis 分子名称: Bacteriocin lactococcin-A, Lactococcin-A immunity protein, Mannose-specific PTS system, ... 著者 Wang, J.W. 登録日 2022-11-12 公開日 2023-02-08 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Structural Basis of the Mechanisms of Action and Immunity of Lactococcin A, a Class IId Bacteriocin. Appl.Environ.Microbiol., 89, 2023
2RQV	Solution structure of SH3CI domain of Bem1p 分子名称: Bud emergence protein 1 著者 Takaku, T, Ogura, K, Inagaki, F. 登録日 2009-12-21 公開日 2010-04-21 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42 J.Biol.Chem., 285, 2010
5SOM	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000835985505 - (S) isomer 分子名称: Non-structural protein 3, [(3S)-2-oxopiperidin-3-yl]methyl [4-(1H-pyrazol-1-yl)phenyl]acetate 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
4USW	Crystal structure of human soluble Adenylyl Cyclase with ATP 分子名称: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ADENYLATE CYCLASE TYPE 10, ... 著者 Kleinboelting, S, Steegborn, C. 登録日 2014-07-13 公開日 2014-07-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Analysis of Human Soluble Adenylyl Cyclase and Crystal Structures of its Nucleotide Complexes -Implications for Cyclase Catalysis and Evolution. FEBS J., 281, 2014
5SQZ	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z1039058598 分子名称: N-[(pyridin-2-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
8HR7	Structure of RdrA-RdrB complex 分子名称: Adenosine deaminase, Archaeal ATPase 著者 Gao, Y. 登録日 2022-12-15 公開日 2023-02-01 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.96 Å) 主引用文献 Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
4V16	KlHsv2 with loop 6CD replaced by a Gly-Ser linker 分子名称: SVP1-LIKE PROTEIN 2 著者 Busse, R.A, Scacioc, A, Krick, R, Perez-Lara, A, Thumm, M, Kuhnel, K. 登録日 2014-09-25 公開日 2015-04-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Characterization of Proppin-Phosphoinositide Binding and Role of Loop 6Cd in Proppin-Membrane Binding. Biophys.J., 108, 2015
2RR7	Microtubule Binding Domain of DYNEIN-C 分子名称: Dynein heavy chain 9 著者 Kato, Y, Yagi, T, Ohki, S, Burgess, S, Honda, S, Kamiya, R, Tanokura, M. 登録日 2010-06-04 公開日 2011-06-08 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure of the microtubule-binding domain of flagellar dynein Structure, 22, 2014
5SR2	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with EN300-36602160 分子名称: (1R,2S)-1-[4-(cyclopropylcarbamamido)benzamido]-4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
2R8G	Selectivity of Nucleoside Triphosphate Incorporation Opposite 1,N2-Propanodeoxyguanosine (PdG) by the Sulfolobus solfataricus DNA Polymerase Dpo4 Polymerase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*DGP*DGP*DGP*DGP*DGP*DAP*DAP*DGP*DGP*DAP*DTP*DTP*DT)-3', 5'-D(*DTP*DCP*DAP*DCP*(P)P*DGP*DAP*DAP*DAP*DTP*DCP*DCP*DTP*DTP*DCP*DCP*DCP*DCP*DC)-3', ... 著者 Wang, Y, Saleh, S, Marnette, L.J, Egli, M, Stone, M.P. 登録日 2007-09-10 公開日 2008-07-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV Biochemistry, 47, 2008
8H98	Crystal structure of chemically modified E. coli ThrS catalytic domain 1 分子名称: N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION 著者 Qiao, H, Xia, M, Wang, J, Fang, P. 登録日 2022-10-25 公開日 2023-02-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
4UQS	Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 3-Bromo-7-Nitroindazole 分子名称: 3-BROMO-7-NITROINDAZOLE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Holden, J.K, Poulos, T.L. 登録日 2014-06-24 公開日 2014-09-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Identification of Redox Partners and Development of a Novel Chimeric Bacterial Nitric Oxide Synthase for Structure Activity Analyses. J.Biol.Chem., 289, 2014
8H1B	Crystal structure of MnmM from S. aureus complexed with SAM and tRNA anti-codon stem loop (ASL) (1.55 A) 分子名称: RNA (5'-R(*AP*CP*GP*GP*AP*CP*UP*UP*UP*GP*AP*CP*UP*CP*CP*GP*U)-3'), S-ADENOSYLMETHIONINE, SODIUM ION, ... 著者 Kim, J, Cho, G, Lee, J. 登録日 2022-10-01 公開日 2023-01-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification. Nucleic Acids Res., 51, 2023
5SR4	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z2479779298 - (R,S) and (S,R) isomers 分子名称: (1R,3S)-3-[(7-fluoro-9H-pyrimido[4,5-b]indol-4-yl)amino]cyclopentan-1-ol, (1S,3R)-3-[(7-fluoro-9H-pyrimido[4,5-b]indol-4-yl)amino]cyclopentan-1-ol, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023

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