PDB: 226262 件ウェブページステータス検索Chemie searchBIRD

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4WEI	Crystal structure of the F4 fimbrial adhesin FaeG in complex with lactose 分子名称: K88 fimbrial protein AD, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose 著者 Moonens, K, Van den Broeck, I, De Kerpel, M, Deboeck, F, Raymaekers, H, Remaut, H, De Greve, H. 登録日 2014-09-10 公開日 2015-02-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and Functional Insight into the Carbohydrate Receptor Binding of F4 Fimbriae-producing Enterotoxigenic Escherichia coli. J.Biol.Chem., 290, 2015
5SQR	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with REAL300016493575 - (R,S) isomer 分子名称: (2R,3S)-1-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-sulfonyl)-2-methylpiperidine-3-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
2RLN	THERMODYNAMIC AND STRUCTURAL CONSEQUENCES OF CHANGING A SULPHUR ATOM TO A METHYLENE GROUP IN THE M13NLE MUTATION IN RIBONUCLEASE S 分子名称: RIBONUCLEASE, RIBONUCLEASE S (S-PROTEIN), SULFATE ION 著者 Ratnaparkhi, G, Varadarajan, R. 登録日 1994-07-11 公開日 1994-11-01 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Thermodynamic and structural consequences of changing a sulfur atom to a methylene group in the M13Nle mutation in ribonuclease-S. Biochemistry, 33, 1994
4UTC	Crystal structure of dengue 2 virus envelope glycoprotein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN E, ... 著者 Kikuti, C, Rouvinski, A, Guardado-Calvo, P, Barba-Spaeth, G, Duquerroy, S, Vaney, M.C, Rey, F.A. 登録日 2014-07-18 公開日 2015-01-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses. Nature, 520, 2015
8HBR	The C-terminal domain of Spiral2 分子名称: TOG domain-containing protein 著者 Hayashi, I. 登録日 2022-10-30 公開日 2023-01-18 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the C-terminal domain of the plant-specific microtubule-associated protein Spiral2. Acta Crystallogr.,Sect.F, 79, 2023
5SQT	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000833624464 - (R,R) and (S,S) isomers 分子名称: (3R,4R)-4-methyl-1-(2-oxo-2,3-dihydro-1,3-benzoxazole-7-carbonyl)pyrrolidine-3-carboxylic acid, (3S,4S)-4-methyl-1-(2-oxo-2,3-dihydro-1,3-benzoxazole-7-carbonyl)pyrrolidine-3-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
2RLZ	Solid-State MAS NMR structure of the dimer Crh 分子名称: HPr-like protein crh 著者 Loquet, A, Bardiaux, B, Gardiennet, C, Blanchet, C, Baldus, M, Nilges, M, Malliavin, T, Bockmann, A. 登録日 2007-09-04 公開日 2008-06-17 最終更新日 2024-05-29 実験手法 SOLID-STATE NMR 主引用文献 3D structure determination of the Crh protein from highly ambiguous solid-state NMR restraints. J.Am.Chem.Soc., 130, 2008
8HDW	Cyanophage Pam3 Sheath-tube 分子名称: Pam3 sheath protein, pam3 tube 著者 Yang, F, Jiang, Y.L, Zhou, C.Z. 登録日 2022-11-06 公開日 2023-01-18 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Fine structure and assembly pattern of a minimal myophage Pam3. Proc.Natl.Acad.Sci.USA, 120, 2023
4UV7	The complex structure of extracellular domain of EGFR and GC1118A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIDERMAL GROWTH FACTOR RECEPTOR, ... 著者 Yoo, J.H, Cho, H.S. 登録日 2014-08-05 公開日 2015-10-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Gc1118, an Anti-Egfr Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity Against High-Affinity Egfr Ligands. Mol.Cancer Ther., 15, 2016
2RT9	Solution structure of a regulatory domain of meiosis inhibitor 分子名称: F-box only protein 43, ZINC ION 著者 Shoji, S, Muto, Y, Ikeda, M, He, F, Tsuda, K, Ohsawa, N, Akasaka, R, Terada, T, Wakiyama, M, Shirouzu, M, Yokoyama, S. 登録日 2013-07-05 公開日 2014-07-16 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation FEBS Open Bio, 4, 2014
5SQY	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5211314110 - (S,S) isomer 分子名称: (1S,2S)-1-{[4-(cyclopropylcarbamamido)-1,3-benzothiazole-7-carbonyl]amino}-4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
4USM	WcbL complex with glycerol bound to sugar site 分子名称: CHLORIDE ION, GLYCEROL, PUTATIVE SUGAR KINASE 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-10 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
8GXU	1 ATP-bound V1EG of V/A-ATPase from Thermus thermophilus 分子名称: ADENOSINE-5'-TRIPHOSPHATE, SULFATE ION, V-type ATP synthase alpha chain, ... 著者 Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. 登録日 2022-09-21 公開日 2023-01-25 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
2RV2	Solution structures of the DNA-binding domain (ZF14) of immune-related zinc-finger protein ZFAT 分子名称: ZINC ION, Zinc finger protein ZFAT 著者 Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. 登録日 2015-01-26 公開日 2015-04-08 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT J.Struct.Funct.Genom., 16, 2015
5SSO	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5198562519 - (R) and (S) isomers 分子名称: (8R)-6-(2-amino-7-fluoro-9H-pyrimido[4,5-b]indol-4-yl)-8-fluoro-6-azaspiro[3.4]octane-8-carboxylic acid, (8S)-6-(2-amino-7-fluoro-9H-pyrimido[4,5-b]indol-4-yl)-8-fluoro-6-azaspiro[3.4]octane-8-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
4V7I	Ribosome-SecY complex. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Gumbart, J.C, Trabuco, L.G, Schreiner, E, Villa, E, Schulten, K. 登録日 2009-10-21 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (9.6 Å) 主引用文献 Regulation of the protein-conducting channel by a bound ribosome. Structure, 17, 2009
8GXY	2 sulfate-bound V1EG of V/A-ATPase from Thermus thermophilus. 分子名称: SULFATE ION, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... 著者 Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. 登録日 2022-09-21 公開日 2023-01-25 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
2SEC	STRUCTURAL COMPARISON OF TWO SERINE PROTEINASE-PROTEIN INHIBITOR COMPLEXES. EGLIN-C-SUBTILISIN CARLSBERG AND CI-2-SUBTILISIN NOVO 分子名称: CALCIUM ION, EGLIN C, SUBTILISIN CARLSBERG 著者 Mcphalen, C.A, James, M.N.G. 登録日 1988-09-05 公開日 1988-09-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo. Biochemistry, 27, 1988
4UTM	XenA - Reduced - Y183F variant in complex with 8-hydroxycoumarin 分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 8-HYDROXYCOUMARIN, SULFATE ION, ... 著者 Werther, T, Dobbek, H. 登録日 2014-07-21 公開日 2015-08-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Redox-dependent substrate-cofactor interactions in the Michaelis-complex of a flavin-dependent oxidoreductase Nat Commun, 8, 2017
8HC4	SARS-CoV-2 wildtype spike trimer (6P) in complex with 3 YB9-258 Fabs and 3 R1-32 Fabs (3 RBD up) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, ... 著者 Liu, B, Gao, X, Chen, Q, Li, Z, Su, M, He, J, Xiong, X. 登録日 2022-11-01 公開日 2023-01-25 最終更新日 2023-05-03 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants. Nat Commun, 14, 2023
5SS8	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINCny000002NPIr 分子名称: (4-{[(thieno[3,2-b]pyridine-7-carbonyl)amino]methyl}phenyl)acetic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
5SSM	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5459166256 - (R,R) and (S,S) isomers 分子名称: (1R,2R)-1-[(1H-benzimidazole-5-carbonyl)amino]-4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid, (1S,2S)-1-[(1H-benzimidazole-5-carbonyl)amino]-4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
2RMF	Human Urocortin 1 分子名称: Urocortin 著者 Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. 登録日 2007-10-16 公開日 2008-01-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Common and divergent structural features of a series of corticotropin releasing factor-related peptides J.Am.Chem.Soc., 129, 2007
8H26	Crystal structure of MnmM from S. aureus complexed with SAH (1.50 A) 分子名称: 16S rRNA (Cytosine(1402)-N(4))-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Kim, J, Cho, G, Lee, J. 登録日 2022-10-05 公開日 2023-01-18 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of MnmM from S. aureus complexed with SAH (1.50 A) To Be Published
4UVY	Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-methoxy-1,2- dihydroisoquinolin-1-one 分子名称: 3-(4-chlorophenyl)-5-methoxyisoquinolin-1(2H)-one, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Narwal, M, Lehtio, L. 登録日 2014-08-08 公開日 2015-07-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro. Bioorg.Med.Chem., 23, 2015

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