PDB: 224931 件ウェブページステータス検索Chemie searchBIRD

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4DB5	Crystal structure of Rabbit GITRL 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tumor necrosis factor ligand superfamily member 18 著者 Kumar, P.R, Bhosle, R, Gizzi, A, Scott Glenn, A, Chowhury, S, Hillerich, B, Seidel, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) 登録日 2012-01-13 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.522 Å) 主引用文献 Crystal structure of GITRL from Oryctolagus cuniculus to be published
2IOY	Crystal structure of Thermoanaerobacter tengcongensis ribose binding protein 分子名称: Periplasmic sugar-binding protein, beta-D-ribopyranose 著者 Cuneo, M.J, Hellinga, H.W. 登録日 2006-10-11 公開日 2007-03-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The backbone structure of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein is essentially identical to its mesophilic E. coli homolog. Bmc Struct.Biol., 8, 2008
2IPK	Crystal Structure of the MHC Class II Molecule HLA-DR1 in Complex with the Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine) and the Superantigen, SEC3 Variant 3B2 分子名称: Enterotoxin type C-3, HA related Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine), ... 著者 Nguyen, T.T, Stern, L.J. 登録日 2006-10-12 公開日 2007-03-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells. Nat.Chem.Biol., 3, 2007
4DNT	Crystal structure of the CusBA heavy-metal efflux complex from Escherichia coli, mutant 分子名称: Cation efflux system protein CusA, Cation efflux system protein CusB 著者 Su, C.-C, Long, F, Yu, E. 登録日 2012-02-09 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System. J.Mol.Biol., 422, 2012
2IDU	Structure of M98Q mutant of amicyanin, Cu(I) 分子名称: Amicyanin, COPPER (I) ION 著者 Carrell, C.J, Ma, J.K, Antholine, W, Hosler, J.P, Mathews, F.S, Davidson, V.L. 登録日 2006-09-15 公開日 2007-03-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Generation of Novel Copper Sites by Mutation of the Axial Ligand of Amicyanin. Atomic Resolution Structures and Spectroscopic Properties Biochemistry, 46, 2007
4DQ7	Structural Investigation of Bacteriophage Phi6 Lysin (V207F mutant) 分子名称: Membrane protein Phi6 P5 著者 Dessau, M.A, Modis, Y. 登録日 2012-02-15 公開日 2013-01-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme. PLoS Genet, 8, 2012
2IHT	Carboxyethylarginine synthase from Streptomyces clavuligerus: SeMet structure 分子名称: Carboxyethylarginine synthase, GLYCEROL, MAGNESIUM ION, ... 著者 Caines, M.E, Schofield, C.J. 登録日 2006-09-27 公開日 2007-09-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and mechanistic studies on N(2)-(2-carboxyethyl)arginine synthase. Biochem.Biophys.Res.Commun., 385, 2009
4DR3	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with streptomycin bound 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-16 公開日 2012-11-14 最終更新日 2013-01-30 実験手法 X-RAY DIFFRACTION (3.348 Å) 主引用文献 A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
2IMC	Clostridium botulinum Neurotoxin Serotype A Light Chain, Residues 1-424 分子名称: Botulinum neurotoxin A light-chain, ZINC ION 著者 Silvaggi, N.R, Allen, K.N. 登録日 2006-10-04 公開日 2007-06-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain Complexed with Small-Molecule Inhibitors Highlight Active-Site Flexibility. Chem.Biol., 14, 2007
4DUS	Structure of Bace-1 (Beta-Secretase) in complex with N-((2S,3R)-1-(4-fluorophenyl)-3-hydroxy-4-((6'-neopentyl-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl)amino)butan-2-yl)acetamide 分子名称: Beta-secretase 1, GLYCEROL, IODIDE ION, ... 著者 Sickmier, E.A. 登録日 2012-02-22 公開日 2012-10-10 最終更新日 2014-07-02 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of beta-Secretase. ACS Med Chem Lett, 3, 2012
2IO0	Crystal structure of human Senp2 in complex with preSUMO-2 分子名称: SULFATE ION, Sentrin-specific protease 2, Small ubiquitin-related modifier 2 precursor 著者 Reverter, D, Lima, C.D. 登録日 2006-10-09 公開日 2006-11-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates. Nat.Struct.Mol.Biol., 13, 2006
4DLX	H-Ras Set 1 CaCl2/DTE, ordered off 分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ... 著者 Holzapfel, G, Mattos, C. 登録日 2012-02-06 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.731 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
4DMG	Thermus thermophilus m5C1942 methyltransferase RlmO 分子名称: Putative uncharacterized protein TTHA1493, S-ADENOSYLMETHIONINE 著者 Larsen, H.G, Rasmussen, A, Giessing, A.M.B, Jogl, G, Kirpekar, F. 登録日 2012-02-07 公開日 2012-06-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Identification and Characterization of the Thermus thermophilus 5-Methylcytidine (m5C) Methyltransferase Modifying 23 S Ribosomal RNA (rRNA) Base C1942. J.Biol.Chem., 287, 2012
4DV5	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A914G, bound with streptomycin 分子名称: 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-22 公開日 2013-02-27 実験手法 X-RAY DIFFRACTION (3.683 Å) 主引用文献 A structural basis for streptomycin resistance To be Published
2IPL	Crystal structure of a disulfide mutant glucose binding protein 分子名称: CALCIUM ION, D-galactose-binding periplasmic protein, beta-D-glucopyranose 著者 Cuneo, M.J, Hellinga, H.W. 登録日 2006-10-12 公開日 2007-03-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 The free energy cost of domain reorganization in E. coli glucose binding protein To be Published
4DX7	Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop 分子名称: Acriflavine resistance protein B, DARPIN, DECANE, ... 著者 Eicher, T, Cha, H, Seeger, M.A, Brandstaetter, L, El-Delik, J, Bohnert, J.A, Kern, W.V, Verrey, F, Gruetter, M.G, Diederichs, K, Pos, K.M. 登録日 2012-02-27 公開日 2012-05-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.253 Å) 主引用文献 Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. Proc.Natl.Acad.Sci.USA, 109, 2012
4DBB	The PTB domain of Mint1 is autoinhibited by a helix in the C-terminal linker region 分子名称: ACETIC ACID, Amyloid beta A4 precursor protein-binding family A member 1, CHLORIDE ION, ... 著者 Tomchick, D.R, Rizo, J, Ho, A, Xu, Y. 登録日 2012-01-13 公開日 2012-03-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing. Proc.Natl.Acad.Sci.USA, 109, 2012
4DB7	Crystal structure of B. anthracis DHPS with compound 25 分子名称: 3-(7-amino-4,5-dioxo-1,4,5,6-tetrahydropyrimido[4,5-c]pyridazin-3-yl)propanoic acid, Dihydropteroate Synthase, SULFATE ION 著者 Hammoudeh, D, Lee, R.E, White, S.W. 登録日 2012-01-13 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Based Design of Novel Pyrimido[4,5-c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity. Chemmedchem, 7, 2012
2IMA	Clostridium botulinum Neurotoxin Serotype A Light Chain Inhibited by 2,4-dichlorocinnamic hydroxamate 分子名称: (2E)-3-(2,4-DICHLOROPHENYL)-N-HYDROXYACRYLAMIDE, Botulinum neurotoxin A light-chain, ZINC ION 著者 Silvaggi, N.R, Allen, K.N. 登録日 2006-10-04 公開日 2007-06-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain Complexed with Small-Molecule Inhibitors Highlight Active-Site Flexibility. Chem.Biol., 14, 2007
2IMS	The X-ray Structure of a Bak Homodimer Reveals an Inhibitory Zinc Binding Site 分子名称: Apoptosis regulator BAK, ZINC ION 著者 Moldoveanu, T, Liu, Q, Tocilj, A, Watson, M, Shore, G.C, Gehring, K.B. 登録日 2006-10-04 公開日 2006-12-26 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 The X-Ray Structure of a BAK Homodimer Reveals an Inhibitory Zinc Binding Site Mol.Cell, 24, 2006
4DI3	Crystal structure of a 2:1 complex of Treponema pallidum TatP(T) (Tp0957) bound to TatT (Tp0956) 分子名称: TatP(T) (Tp0957), TatT (Tp0956) 著者 Brautigam, C.A, Deka, R.K, Norgard, M.V. 登録日 2012-01-30 公開日 2012-05-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structural and Thermodynamic Characterization of the Interaction between Two Periplasmic Treponema pallidum Lipoproteins that are Components of a TPR-Protein-Associated TRAP Transporter (TPAT). J.Mol.Biol., 420, 2012
4DJP	Crystal Structure of wild-type HIV-1 Protease in Complex with MKP73 分子名称: PHOSPHATE ION, Pol polyprotein, methyl (2S)-3-({[(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl][(2S)-2-methylbutyl]amino}-1-phenylbutan-2-yl]carbamoyl}oxy)-2-methylpropanoate 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2012-02-02 公開日 2012-08-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance. J.Med.Chem., 55, 2012
2IPQ	Crystal structure of C-terminal domain of Salmonella Enterica protein STY4665, PFAM DUF1528 分子名称: Hypothetical protein STY4665 著者 Ramagopal, U.A, Bonanno, J.B, Gilmore, J, Toro, R, Bain, K.T, Reyes, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2006-10-12 公開日 2006-11-07 最終更新日 2021-02-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of C-terminal domain of Hypothetical protein STY4665 To be Published
4DJR	Crystal Structure of wild-type HIV-1 Protease in Complex with MKP97 分子名称: PHOSPHATE ION, Pol polyprotein, [(2S)-5-oxopyrrolidin-2-yl]methyl [(2S,3R)-4-{(1,3-benzothiazol-6-ylsulfonyl)[(2S)-2-methylbutyl]amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2012-02-02 公開日 2012-08-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance. J.Med.Chem., 55, 2012
4DK5	Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine inhibitor 分子名称: 4-(2-[(6-methoxypyridin-3-yl)amino]-5-{[4-(methylsulfonyl)piperazin-1-yl]methyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION 著者 Whittington, D.A, Tang, J, Yakowec, P. 登録日 2012-02-03 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases. J.Med.Chem., 55, 2012

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