8XOV
| The Crystal Structure of N-terminal kinase domain of human RSK-1 from Biortus. | 分子名称: | 1,2-ETHANEDIOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-1 | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Zhang, B. | 登録日 | 2024-01-02 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The Crystal Structure of N-terminal kinase domain of human RSK-1 from Biortus. To Be Published
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8XOU
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8XOT
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8XOP
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8XOO
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8XON
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8XOM
| Cryo-EM structure of human ABCC4 in complex with ANP-bound in NBD1 and METHOTREXATE | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | 著者 | Zhang, P.F, Liu, Z. | 登録日 | 2024-01-01 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 2024
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8XOL
| Cryo-EM structure of human ABCC4 with ANP bound in NBD1 | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | 著者 | Zhang, P.F, Liu, Z. | 登録日 | 2024-01-01 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 2024
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8XOJ
| Cryo-EM structure of GPR30-Gq complex structure in the presence of G-1 | 分子名称: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, H, Xu, P, Xu, H.E. | 登録日 | 2024-01-01 | 公開日 | 2024-04-10 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOI
| Cryo-EM structure of GPR30-Gq complex structure in the presence of fulvestrant | 分子名称: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, H, Xu, P, Xu, H.E. | 登録日 | 2024-01-01 | 公開日 | 2024-04-10 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOH
| Cryo-EM structure of GPR30-Gq complex structure in the presence of E2 | 分子名称: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, H, Xu, P, Xu, H.E. | 登録日 | 2024-01-01 | 公開日 | 2024-04-10 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOG
| Cryo-EM structure of apo-GPR30-Gq complex structure | 分子名称: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, H, Xu, P, Xu, H.E. | 登録日 | 2024-01-01 | 公開日 | 2024-04-10 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOF
| Cryo-EM structure of Lys05 bound GPR30-Gq complex structure | 分子名称: | G protein subunit q, G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Liu, H, Xu, P, Xu, H.E. | 登録日 | 2024-01-01 | 公開日 | 2024-04-10 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOB
| VMAT2 protonated state | 分子名称: | Synaptic vesicular amine transporter,transporter B | 著者 | Jiang, D.H, Wu, D. | 登録日 | 2023-12-31 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | VMAT2 protonated state To Be Published
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8XOA
| VMAT2 complex with MPP+ | 分子名称: | 1-methyl-4-phenylpyridin-1-ium, Synaptic vesicular amine transporter,Synaptic vesicular amine transporter,transporterA | 著者 | Jiang, D.H, Wu, D. | 登録日 | 2023-12-31 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | VMAT2 complex with MPP+ To Be Published
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8XO9
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8XNK
| Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | 著者 | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | 登録日 | 2023-12-30 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | 主引用文献 | Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published
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8XNH
| Nipah virus fusion glycoprotein in complex with a broadly neutralizing antibody 5C8 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5C8-VH, 5C8-VL, ... | 著者 | Fan, P.F, Ren, Y, Yu, C.M, Chen, W. | 登録日 | 2023-12-30 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Nipah virus fusion glycoprotein in complex with a broadly neutralizing antibody 1D6 To Be Published
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8XNG
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8XNF
| Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P) in complex with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | 登録日 | 2023-12-29 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86.1, EG.5, EG.5.1 and HV.1 sub-variants To Be Published
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8XN9
| Nipah virus fusion glycoprotein in complex with a broadly neutralizing antibody 1D6 | 分子名称: | 1D6 VH, 1D6 VL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Fan, P.F, Ren, Y, Yu, C.M, Chen, W. | 登録日 | 2023-12-29 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (1.99 Å) | 主引用文献 | Nipah virus fusion glycoprotein in complex with a broadly neutralizing antibody 1D6 To Be Published
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8XN8
| The Crystal Structure of SRC from Biortus. | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C. | 登録日 | 2023-12-29 | 公開日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Crystal Structure of SRC from Biortus. To Be Published
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8XN7
| Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with compound 9f | 分子名称: | 5-amino-2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-8-(2-(trifluoromethyl)benzyl)pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase kinase kinase kinase 1 | 著者 | Huang, W.X, Liu, R, Ding, K. | 登録日 | 2023-12-29 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery of 5-aminopyrido[2,3-d]pyrimidin-7(8H)-one derivatives as new hematopoietic progenitor kinase 1 (HPK1) inhibitors. Eur.J.Med.Chem., 269, 2024
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8XN6
| The Crystal Structure of GSK3b from Biortus. | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glycogen synthase kinase-3 beta, ... | 著者 | Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B. | 登録日 | 2023-12-29 | 公開日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Crystal Structure of GSK3b from Biortus. To Be Published
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8XN5
| Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P) in complex with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | 著者 | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | 登録日 | 2023-12-29 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | 主引用文献 | Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published
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