PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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8H1W	Serine Palmitoyltransferase from Sphingobacterium multivorum 分子名称: 1,2-ETHANEDIOL, Serine palmitoyltransferase 著者 Takahashi, A, Murakami, T, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T. 登録日 2022-10-04 公開日 2023-08-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum. J.Biol.Chem., 299, 2023
8H1Q	Serine Palmitoyltransferase from Sphingobacterium multivorum complexed with L-serine 分子名称: 1,2-ETHANEDIOL, Serine palmitoyltransferase, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE 著者 Murakami, T, Takahashi, A, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T. 登録日 2022-10-03 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum. J.Biol.Chem., 299, 2023
7O58	Human phosphomannomutase 2 (PMM2) with mutation T237M in complex with the activator glucose 1,6-bisphosphate 分子名称: 1,6-di-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... 著者 Ramon-Maiques, S, Briso-Montiano, A, Del Cano-Ochoa, F, Vilas, A, Perez, B, Rubio, V. 登録日 2021-04-08 公開日 2022-02-02 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45, 2022
7O4G	Human phosphomannomutase 2 (PMM2) wild-type soaked with the activator glucose 1,6-bisphosphate 分子名称: 1,6-di-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... 著者 Ramon-Maiques, S, Briso-Montiano, A, Del Cano-Ochoa, F, Vilas, A, Perez, B, Rubio, V. 登録日 2021-04-06 公開日 2022-02-02 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45, 2022
8QV9	Hexameric HIV-1 CA in complex with DDD01829021 分子名称: 1,2-ETHANEDIOL, 7-bromanyl-3-(phenylmethyl)-1~{H}-benzimidazol-2-one, Spacer peptide 1 著者 Petit, A.P, Fyfe, P.K. 登録日 2023-10-17 公開日 2024-03-27 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Application of an NMR/Crystallography Fragment Screening Platform for the Assessment and Rapid Discovery of New HIV-CA Binding Fragments. Chemmedchem, 19, 2024
6VKE	Crystal Structure of Inhibitor JNJ-40012665 in Complex with Prefusion RSV F Glycoprotein 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 4-(5-chloro-2-{[1-(3,4-dimethoxyphenyl)-2-oxo-1,2-dihydro-3H-imidazo[4,5-c]pyridin-3-yl]methyl}-1H-indol-1-yl)butanenitrile, CHLORIDE ION, ... 著者 McLellan, J.S. 登録日 2020-01-20 公開日 2020-05-27 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of 3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (JNJ-53718678), a Potent and Orally Bioavailable Fusion Inhibitor of Respiratory Syncytial Virus. J.Med.Chem., 63, 2020
6VKV	Co-crystal structure of GS-6207 bound to HIV-1 capsid hexamer 分子名称: CHLORIDE ION, Capsid protein p24, IODIDE ION, ... 著者 Bester, S.M, Kvaratskhelia, M. 登録日 2020-01-22 公開日 2020-10-21 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Structural and mechanistic bases for a potent HIV-1 capsid inhibitor. Science, 370, 2020
8QD3	Ayg1p in complex with 1,3,6,8-Tetrahydroxynaphthalene 分子名称: 1,2-ETHANEDIOL, FLAVIOLIN, Pigment biosynthesis protein yellowish-green 1, ... 著者 Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. 登録日 2023-08-28 公開日 2024-03-13 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
7R73	Crystal structure of llama VHH antibody D7 in complex with HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, Llama antibody D7 著者 Zhou, T, Kwong, P.D. 登録日 2021-06-24 公開日 2022-03-30 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
6XQI	Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A 分子名称: ASN-PRO-LEU-GLU-PHE-LEU, Protein Vpr, UV excision repair protein RAD23 homolog A, ... 著者 Calero, G.C, Wu, Y, Weiss, S.C. 登録日 2020-07-09 公開日 2021-08-11 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A. Nat Commun, 12, 2021
7LOH	Structure of the HIV-1 gp41 transmembrane domain and cytoplasmic tail 分子名称: Transmembrane protein gp41 著者 Piai, A, Fu, Q, Sharp, A.K, Bighi, B, Brown, A.M, Chou, J.J. 登録日 2021-02-10 公開日 2021-04-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR Model of the Entire Membrane-Interacting Region of the HIV-1 Fusion Protein and Its Perturbation of Membrane Morphology. J.Am.Chem.Soc., 143, 2021
8E4H	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-18 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E3R	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-17 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EK3	Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAATGGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-19 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EKV	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGATGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*TP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*AP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8ENG	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) with Hemi-methylated CpG (forward strand) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*G*(5CM)P*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-29 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E3K	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-17 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
6Y23	DDR1 kinase autoinhibited by its juxtamembrane region 分子名称: Epithelial discoidin domain-containing receptor 1, SULFATE ION 著者 Sammon, D, Hohenester, E, Leitinger, B. 登録日 2020-02-14 公開日 2020-09-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Two-step release of kinase autoinhibition in discoidin domain receptor 1. Proc.Natl.Acad.Sci.USA, 117, 2020
8EKZ	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGGAGAAGTAGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*GP*AP*GP*AP*AP*GP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*TP*AP*CP*TP*TP*CP*TP*CP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EMD	Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-27 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E5Y	Human PU.1 ETS-Domain Bound to d(AATAAGCGGAAGTGGG) Acetate Free at pH 5.4 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EE9	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAATGGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-06 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
6GPJ	Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4F-Man 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, GDP-mannose 4,6 dehydratase, ... 著者 Pfeiffer, M, Krojer, T, Johansson, C, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Nidetzky, B, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2018-06-06 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase. Acs Catalysis, 9, 2019
8EK8	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAGAAGGG) 分子名称: DNA (5'-D(*AP*TP*AP*AP*AP*AP*GP*GP*AP*GP*AP*AP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*TP*TP*CP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-20 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
9C7L	Crystal structure of pentalenene synthase variant F76A complexed with 2-fluorofarnesyl diphosphate 分子名称: (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION, Pentalenene synthase 著者 Prem Kumar, R, Ellenburg, W.H, Oprian, D.D. 登録日 2024-06-10 公開日 2024-11-06 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Caryolan-1-ol Synthase, a Sesquiterpene Synthase Catalyzing an Initial Anti-Markovnikov Cyclization Reaction. Biochemistry, 63, 2024

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