PDB: 19255 件ウェブページステータス検索Chemie searchBIRD

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4QTI	Crystal structure of human uPAR in complex with anti-uPAR Fab 8B12 分子名称: Urokinase plasminogen activator surface receptor, anti-uPAR antibody, heavy chain, ... 著者 Zhao, B, Yuan, C, Luo, Z, Huang, M. 登録日 2014-07-08 公開日 2015-02-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation. J.Mol.Biol., 427, 2015
4R1M	Crystal structure of a Putative Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.48 A resolution 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-08-06 公開日 2014-08-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Crystal structure of a Hypothetical Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.48 A resolution To be published
4R95	BACE-1 in complex with 2-(((1R,3S)-3-(((R)-4-(2-cyclohexylethyl)-2-iminio-1-methyl-5-oxoimidazolidin-4-yl)methyl)cyclohexyl)amino)quinolin-1-ium 分子名称: (2E,5R)-5-(2-cyclohexylethyl)-2-imino-3-methyl-5-{[(1S,3R)-3-(quinolin-2-ylamino)cyclohexyl]methyl}imidazolidin-4-one, Beta-secretase 1, L(+)-TARTARIC ACID 著者 Orth, P, Strickland, C, Caldwell, J.P. 登録日 2014-09-03 公開日 2014-11-05 最終更新日 2014-12-17 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Discovery of potent iminoheterocycle BACE1 inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
4QSA	Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, Carbonic anhydrase 2, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-07-03 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.501 Å) 主引用文献 Intrinsic Thermodynamics and Structure Correlation of Benzenesulfonamides with a Pyrimidine Moiety Binding to Carbonic Anhydrases I, II, VII, XII, and XIII Plos One, 9, 2014
3SUP	RB69 DNA Polymerase (Y567A) Ternary Complex with dCTP Opposite 2AP (GC rich sequence) 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*GP*CP*GP*CP*GP*GP*CP*GP*GP*CP*GP*(2DA))-3', 5'-D(P*CP*(2PR)P*TP*CP*GP*CP*CP*GP*CP*CP*GP*CP*GP*CP*GP*G)-3', ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-07-11 公開日 2011-11-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structure of the 2-Aminopurine-Cytosine Base Pair Formed in the Polymerase Active Site of the RB69 Y567A-DNA Polymerase. Biochemistry, 50, 2011
4RGB	Crystal structure of a putative carveol dehydrogenase from Mycobacterium avium bound to NAD 分子名称: Carveol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-09-29 公開日 2014-10-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Sci Rep, 7, 2017
4QSJ	Crystal structure of human carbonic anhydrase isozyme XIII with 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide 分子名称: 1,2-ETHANEDIOL, 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, CITRIC ACID, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-07-04 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Intrinsic Thermodynamics and Structure Correlation of Benzenesulfonamides with a Pyrimidine Moiety Binding to Carbonic Anhydrases I, II, VII, XII, and XIII Plos One, 9, 2014
4R8Y	BACE-1 in complex with (R)-4-(2-cyclohexylethyl)-4-(((R)-1-(2-cyclopentylacetyl)pyrrolidin-3-yl)methyl)-1-methyl-5-oxoimidazolidin-2-iminium 分子名称: (2E,5R)-5-(2-cyclohexylethyl)-5-{[(3R)-1-(cyclopentylacetyl)pyrrolidin-3-yl]methyl}-2-imino-3-methylimidazolidin-4-one, Beta-secretase 1, L(+)-TARTARIC ACID 著者 Orth, P, Caldwell, J.P, Strickland, C. 登録日 2014-09-03 公開日 2014-11-05 最終更新日 2014-12-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of potent iminoheterocycle BACE1 inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
4S34	ERK2 (I84A) in complex with AMP-PNP 分子名称: MAGNESIUM ION, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Livnah, O, Karamansha, Y, Tzarum, N. 登録日 2015-01-26 公開日 2016-01-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Multiple mechanisms render Erk proteins MEK-independent To be Published
4RN3	Crystal structure of a HAD-superfamily hydrolase, subfamily IA, variant 1 (GSU2069) from Geobacter sulfurreducens PCA at 2.15 A resolution 分子名称: 1,2-ETHANEDIOL, HAD superfamily hydrolase, MAGNESIUM ION 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-10-22 公開日 2014-11-26 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of a HAD-superfamily hydrolase, subfamily IA, variant 1 (GSU2069) from Geobacter sulfurreducens PCA at 2.15 A resolution To be published
4RVO	Crystal structure of a Putative Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.41 A resolution 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-11-26 公開日 2014-12-31 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Crystal structure of a Putative Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.41 A resolution To be published
4RM8	Crystal structure of human ezrin in space group P21 分子名称: Ezrin 著者 Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G. 登録日 2014-10-20 公開日 2015-12-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
4S32	Crystal structure of ERK2 AMP-PNP complex 分子名称: MAGNESIUM ION, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Livnah, O, Karamansha, Y, Tzarum, N. 登録日 2015-01-26 公開日 2016-01-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Crystal structure of ERK2 AMP-PNP complex To be Published
4S30	ERK2 intrinsically active mutant (I84A) 分子名称: Mitogen-activated protein kinase 1 著者 Livnah, O, Karamansha, Y. 登録日 2015-01-26 公開日 2016-01-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Multiple mechanisms render Erk proteins MEK-independent To be Published
4QHZ	Crystal structure of a putative glycosyl hydrolase (BDI_3914) from Parabacteroides distasonis ATCC 8503 at 2.13 A resolution 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, putative glycosyl hydrolase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-05-30 公開日 2014-07-30 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Crystal structure of a putative glycosyl hydrolase (BDI_3914) from Parabacteroides distasonis ATCC 8503 at 2.13 A resolution To be published
4Q4Y	Crystal structure of Coxsackievirus A24v soaked with Disialyllacto-N-tetraose (DSLNT) 分子名称: CALCIUM ION, CHLORIDE ION, Coxsackievirus capsid protein VP1, ... 著者 Zocher, G, Stehle, T. 登録日 2014-04-15 公開日 2014-11-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 A sialic Acid binding site in a human picornavirus. Plos Pathog., 10, 2014
4QK4	Crystal structure of human nuclear receptor sf-1 (nr5a1) bound to pip2 at 2.8 a resolution 分子名称: (2S)-3-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, 1,2-ETHANEDIOL, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ... 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2014-06-05 公開日 2014-07-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1. Proc.Natl.Acad.Sci.USA, 111, 2014
4Q9L	P-glycoprotein cocrystallised with QZ-Phe 分子名称: (30F)F(30F)F(30F)F Peptide, Multidrug resistance protein 1A 著者 McGrath, A.P, Szewczyk, P, Chang, G. 登録日 2014-05-01 公開日 2015-03-04 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein. Acta Crystallogr.,Sect.D, 71, 2015
4QP7	Crystal Structure of ERK2 in complex with 2-(1H-pyrazol-4-yl)-5H-pyrrolo[2,3-b]pyrazine 分子名称: 2-(1H-pyrazol-4-yl)-5H-pyrrolo[2,3-b]pyrazine, Mitogen-activated protein kinase 1 著者 Yin, J, Wang, W. 登録日 2014-06-22 公開日 2015-09-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.249 Å) 主引用文献 Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
4Q1Z	Crystal structure of a DUF4876 family protein (BT_1938) from Bacteroides thetaiotaomicron VPI-5482 at 2.50 A resolution 分子名称: DI(HYDROXYETHYL)ETHER, Putative lipoprotein, TRIETHYLENE GLYCOL, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-04-04 公開日 2014-04-23 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of a hypothetical protein (BT1938) from Bacteroides thetaiotaomicron VPI-5482 at 2.50 A resolution To be published
4QP4	Crystal Structure of ERK2 in complex with N-cyclohexyl-9H-purin-6-amine 分子名称: Mitogen-activated protein kinase 1, N-cyclohexyl-9H-purin-6-amine 著者 Yin, J, Wang, W. 登録日 2014-06-22 公開日 2015-09-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
4QPA	Crystal Structure of ERK2 in complex with 7-(1-benzyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine 分子名称: 7-(1-benzyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine, Mitogen-activated protein kinase 1 著者 Yin, J, Wang, W. 登録日 2014-06-22 公開日 2015-09-23 最終更新日 2015-12-16 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
4QP3	Crystal Structure of ERK2 in complex with (S)-2-((9H-purin-6-yl)amino)-3-phenylpropan-1-ol 分子名称: (2S)-3-phenyl-2-(9H-purin-6-ylamino)propan-1-ol, Mitogen-activated protein kinase 1 著者 Yin, J, Wang, W. 登録日 2014-06-22 公開日 2015-09-23 最終更新日 2015-12-16 実験手法 X-RAY DIFFRACTION (2.599 Å) 主引用文献 Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
4QAN	Crystal structure of a cystatin-like protein (RUMGNA_02398) from Ruminococcus gnavus ATCC 29149 at 2.10 A resolution 分子名称: MAGNESIUM ION, hypothetical protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-05-05 公開日 2014-07-23 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of a hypothetical protein (RUMGNA_02398) from Ruminococcus gnavus ATCC 29149 at 2.10 A resolution To be published
4QP2	Crystal Structure of ERKs in complex with 5-chlorobenzo[d]oxazol-2-amine 分子名称: 5-chloro-1,3-benzoxazol-2-amine, IMIDAZOLE, Mitogen-activated protein kinase 1 著者 Yin, J, Wang, W. 登録日 2014-06-22 公開日 2015-09-23 最終更新日 2015-12-16 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors. Bioorg.Med.Chem.Lett., 25, 2015

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