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4UI5
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Crystal structure of human tankyrase 2 in complex with TA-41
分子名称: 8-methoxy-2-(4-methylphenyl)-3,4-dihydroquinazolin-4-one, GLYCEROL, SULFATE ION, ...
著者Haikarainen, T, Lehtio, L.
登録日2015-03-27
公開日2016-04-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure-Activity Relationships of 2-Arylquinazolin-4-Ones as Highly Selective and Potent Inhibitors of the Tankyrases.
Eur.J.Med.Chem., 118, 2016
4HK6
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BU of 4hk6 by Molmil
Crystal structure of Cordyceps militaris IDCase in complex with 5-nitro-uracil
分子名称: 5-nitrouracil, Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S, Zhu, J, Ding, J.
登録日2012-10-15
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4V7F
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BU of 4v7f by Molmil
Arx1 pre-60S particle.
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Leidig, C, Thoms, M, Holdermann, I, Bradatsch, B, Berninghausen, O, Bange, G, Sinning, I, Hurt, E, Beckmann, R.
登録日2013-12-10
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (8.7 Å)
主引用文献60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle.
Nat Commun, 5, 2014
4V2B
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BU of 4v2b by Molmil
rat Unc5D Ig domain 1
分子名称: PROTEIN UNC5D
著者Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
登録日2014-10-08
公開日2014-11-05
最終更新日2015-07-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
8JFK
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BU of 8jfk by Molmil
PhK holoenzyme in inactive state, muscle isoform
分子名称: Calmodulin-1, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ...
著者Yang, X.K, Xiao, J.Y.
登録日2023-05-18
公開日2024-04-03
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Architecture and activation of human muscle phosphorylase kinase.
Nat Commun, 15, 2024
4V0M
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BU of 4v0m by Molmil
Crystal structure of BBS1N in complex with ARL6DN
分子名称: ARF-LIKE SMALL GTPASE, BARDET-BIEDL SYNDROME 1 PROTEIN, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Mourao, A, Lorentzen, E.
登録日2014-09-17
公開日2014-11-19
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structural Basis for Membrane Targeting of the Bbsome by Arl6
Nat.Struct.Mol.Biol., 21, 2014
4V6C
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BU of 4v6c by Molmil
Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, W, Dunkle, J.A, Cate, J.H.D.
登録日2009-06-27
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
4E7P
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BU of 4e7p by Molmil
Crystal structure of receiver domain of putative NarL family response regulator spr1814 from Streptococcus pneumoniae in the presence of the phosphoryl analog beryllofluoride
分子名称: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Response regulator
著者Park, A.K, Moon, J.H, Lee, K.S, Chi, Y.M.
登録日2012-03-18
公開日2012-05-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.892 Å)
主引用文献Crystal structure of receiver domain of putative NarL family response regulator spr1814 from Streptococcus pneumoniae in the absence and presence of the phosphoryl analog beryllofluoride.
Biochem.Biophys.Res.Commun., 421, 2012
4HMZ
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BU of 4hmz by Molmil
Crystal Structure of ChmJ, a 3'-monoepimerase from Streptomyces bikiniensis in complex with dTDP-quinovose
分子名称: 1,2-ETHANEDIOL, Putative 3-epimerase in D-allose pathway, [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate
著者Holden, H.M, Kubiak, R.L.
登録日2012-10-18
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose.
Biochemistry, 51, 2012
4W2H
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BU of 4w2h by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (co-crystallized), mRNA and deacylated tRNA in the P site
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4HK7
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BU of 4hk7 by Molmil
Crystal structure of Cordyceps militaris IDCase in complex with uracil
分子名称: URACIL, Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S, Zhu, J, Ding, J.
登録日2012-10-15
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.189 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4UR6
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BU of 4ur6 by Molmil
Structure of the type III fish antifreeze protein from Zoarces viviparus ZvAFP6
分子名称: SULFATE ION, TYPE III ANTIFREEZE PROTEIN 6
著者Wilkens, C, Poulsen, J.-C.N, Ramloev, H, Lo Leggio, L.
登録日2014-06-26
公開日2014-07-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Purification, Crystal Structure Determination and Functional Characterization of Type III Antifreeze Proteins from the European Eelpout Zoarces Viviparus.
Cryobiology, 69, 2014
4UUR
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BU of 4uur by Molmil
Cold-adapted truncated hemoglobin from the Antarctic marine bacterium Pseudoalteromonas haloplanktis TAC125
分子名称: PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE HEMOGLOBIN-LIKE OXYGEN-BINDING PROTEIN
著者Pesce, A, Giordano, D, Riccio, A, Nardini, M, Caldelli, E, Howes, B, Bustamante, J.P, Boechi, L, Estrin, D, di Prisco, G, Smulevich, G, Verde, C, Bolognesi, M.
登録日2014-07-31
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural Flexibility of the Heme Cavity in the Cold-Adapted Truncated Hemoglobin from the Antarctic Marine Bacterium Pseudoalteromonas Haloplanktis Tac125.
FEBS J., 282, 2015
4HK5
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BU of 4hk5 by Molmil
Crystal structure of Cordyceps militaris IDCase in apo form
分子名称: Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S, Zhu, J, Ding, J.
登録日2012-10-15
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4V0T
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BU of 4v0t by Molmil
Monomeric pseudorabies virus protease pUL26N at 2.1 A resolution
分子名称: UL26
著者Zuehlsdorf, M, Werten, S, Palm, G.J, Hinrichs, W.
登録日2014-09-18
公開日2015-07-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin Pul26N, a Herpesvirus Serine Protease
Plos Pathog., 11, 2015
4V4A
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BU of 4v4a by Molmil
Crystal Structure of the Wild Type Ribosome from E. Coli 70S Ribosome.
分子名称: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S ribosomal protein S10, ...
著者Vila-Sanjurjo, A, Ridgeway, W.K, Seymaner, V, Zhang, W, Santoso, S, Yu, K, Cate, J.H.D.
登録日2003-06-13
公開日2014-07-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (9.5 Å)
主引用文献X-ray crystal structures of the WT and a hyper-accurate ribosome from Escherichia coli
Proc.Natl.Acad.Sci.USA, 100, 2003
4V4T
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BU of 4v4t by Molmil
Crystal structure of the whole ribosomal complex with a stop codon in the A-site.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
登録日2005-10-12
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (6.46 Å)
主引用文献Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
4V55
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BU of 4v55 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin and ribosome recycling factor (RRF).
分子名称: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-17
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
4WAK
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BU of 4wak by Molmil
H. influenzae beta-carbonic anhydrase variant W39V/G41A
分子名称: BICARBONATE ION, Carbonic anhydrase 2, POTASSIUM ION, ...
著者Hoffmann, K.M, Rowlett, R.S.
登録日2014-08-29
公開日2014-12-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Allosteric Reversion of Haemophilus influenzae beta-Carbonic Anhydrase via a Proline Shift.
Biochemistry, 54, 2015
4HN0
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BU of 4hn0 by Molmil
Crystal Structure of ChmJ, a 3'-monoepimerase apoenzyme from Streptomyces bikiniensis
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Putative 3-epimerase in D-allose pathway
著者Holden, H.M, Kubiak, R.L.
登録日2012-10-18
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose.
Biochemistry, 51, 2012
5MGD
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BU of 5mgd by Molmil
STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 6-Galactosyl-lactose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Rico-Diaz, A, Ramirez-Escudero, M, Vizoso Vazquez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J.
登録日2016-11-21
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural features of Aspergillus niger beta-galactosidase define its activity against glycoside linkages.
FEBS J., 284, 2017
2YK5
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BU of 2yk5 by Molmil
Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP.
分子名称: 1,2-ETHANEDIOL, CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE, CYTIDINE-5'-MONOPHOSPHATE, ...
著者Lin, L.Y.C, Rakic, B, Chiu, C.P.C, Lameignere, E, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J.
登録日2011-05-25
公開日2011-08-31
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria Meningitidis
J.Biol.Chem., 286, 2011
4WAM
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BU of 4wam by Molmil
H. influenzae beta-carbonic anhydrase variant W39V/G41A/P48S/A49P
分子名称: PHOSPHATE ION, ZINC ION, beta-carbonic anhydrase
著者Rowlett, R.S, Hoffman, K.M.
登録日2014-08-29
公開日2014-12-31
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Allosteric Reversion of Haemophilus influenzae beta-Carbonic Anhydrase via a Proline Shift.
Biochemistry, 54, 2015
4WB9
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BU of 4wb9 by Molmil
Human ALDH1A1 complexed with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CHLORIDE ION, Retinal dehydrogenase 1, ...
著者Morgan, C.A, Hurley, T.D.
登録日2014-09-02
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.
Chem.Biol.Interact., 234, 2015
4WCW
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BU of 4wcw by Molmil
Ribosomal silencing factor during starvation or stationary phase (RsfS) from Mycobacterium tuberculosis
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, Ribosomal silencing factor RsfS
著者Li, X, Sun, Q, Jiang, C, Yang, K, Hung, L, Zhang, J, Sacchettini, J, TB Structural Genomics Consortium (TBSGC)
登録日2014-09-05
公開日2014-09-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of Ribosomal Silencing Factor Bound to Mycobacterium tuberculosis Ribosome.
Structure, 23, 2015

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