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2L7Z
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NMR Structure of A13 homedomain
分子名称: Homeobox protein Hox-A13
著者Ames, J.
登録日2010-12-27
公開日2011-11-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for sequence specific DNA binding and protein dimerization of HOXA13.
Plos One, 6, 2011
5EWK
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BU of 5ewk by Molmil
Scabin toxin from Streptomyces Scabies in complex with inhibitor PJ34
分子名称: N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, Putative ADP-Ribosyltransferase Scabin
著者Ravulapalli, R, Lyons, B, Merrill, A.R.
登録日2015-11-20
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Scabin, a Novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies.
J.Biol.Chem., 291, 2016
5EWY
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Scabin toxin from Streptomyces Scabies in complex with inhibitor P6E
分子名称: 4-(8-fluoranyl-6-oxidanylidene-1,3,4,5-tetrahydrobenzo[c][1,6]naphthyridin-2-yl)butanoic acid, Putative ADP-Ribosyltransferase Scabin
著者Ravulapalli, R, Lyons, B, Merrill, A.R.
登録日2015-11-22
公開日2016-03-23
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Scabin, a Novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies.
J.Biol.Chem., 291, 2016
7TAW
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BU of 7taw by Molmil
Cryo-EM structure of the Csy-AcrIF24-promoter DNA dimer
分子名称: AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR type I-F/YPEST-associated protein Csy3, ...
著者Mukherjee, I.A, Chang, L.
登録日2021-12-21
公開日2022-09-21
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of AcrIF24 as an anti-CRISPR protein and transcriptional suppressor.
Nat.Chem.Biol., 18, 2022
7TAX
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BU of 7tax by Molmil
Cryo-EM structure of the Csy-AcrIF24-promoter DNA complex
分子名称: AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR type I-F/YPEST-associated protein Csy3, ...
著者Mukherjee, I.A, Chang, L.
登録日2021-12-21
公開日2022-09-21
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of AcrIF24 as an anti-CRISPR protein and transcriptional suppressor.
Nat.Chem.Biol., 18, 2022
5GKC
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The crystal structure of the CPS-6 H148A/F122A
分子名称: Endonuclease G, mitochondrial
著者Lin, J.L, Yuan, H.S.
登録日2016-07-04
公開日2016-11-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.892 Å)
主引用文献Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res., 44, 2016
7QXS
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BU of 7qxs by Molmil
Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-27
公開日2022-03-02
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
7QXB
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Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-26
公開日2022-03-02
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
4R8U
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S-SAD structure of DINB-DNA Complex
分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA, DNA polymerase IV, ...
著者Kottur, J, Nair, D.T, Weinert, T, Oligeric, V, Wang, M.
登録日2014-09-03
公開日2015-01-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Fast native-SAD phasing for routine macromolecular structure determination
Nat.Methods, 12, 2015
6RLW
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BU of 6rlw by Molmil
Structure of the human 8-oxoguanine DNA Glycosylase hOGG1 in complex with inhibitor TH5487
分子名称: 4-(4-bromanyl-2-oxidanylidene-3~{H}-benzimidazol-1-yl)-~{N}-(4-iodophenyl)piperidine-1-carboxamide, N-glycosylase/DNA lyase
著者Masuyer, G, Stenmark, P.
登録日2019-05-03
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Targeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Nucleic Acids Res., 48, 2020
5NOC
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BU of 5noc by Molmil
Solution NMR Structure of the C-terminal domain of ParB (Spo0J)
分子名称: Stage 0 sporulation protein J
著者Higman, V.A, Fisher, G.L.M, Dillingham, M.S, Crump, M.P.
登録日2017-04-11
公開日2017-12-13
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere.
Elife, 6, 2017
5NVR
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BU of 5nvr by Molmil
Crystal structure of the Rif1 N-terminal domain (RIF1-NTD) from Saccharomyces cerevisiae
分子名称: Telomere length regulator protein RIF1
著者Bunker, R.D, Shi, T, Thoma, N.H.
登録日2017-05-04
公開日2017-06-14
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends.
Nat. Struct. Mol. Biol., 24, 2017
7JK4
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BU of 7jk4 by Molmil
Structure of Drosophila ORC bound to AT-rich DNA and Cdc6
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (34-MER), ...
著者Schmidt, J.M, Bleichert, F.
登録日2020-07-27
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JK2
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Structure of Drosophila ORC bound to poly(dA/dT) DNA and Cdc6 (conformation 1)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (33-MER), ...
著者Schmidt, J.M, Bleichert, F.
登録日2020-07-27
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JK3
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BU of 7jk3 by Molmil
Structure of Drosophila ORC bound to GC-rich DNA and Cdc6
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (33-MER), ...
著者Schmidt, J.M, Bleichert, F.
登録日2020-07-27
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JK5
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BU of 7jk5 by Molmil
Structure of Drosophila ORC bound to DNA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (32-MER), MAGNESIUM ION, ...
著者Schmidt, J.M, Bleichert, F.
登録日2020-07-27
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
2VZ4
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BU of 2vz4 by Molmil
The N-terminal domain of MerR-like protein TipAL bound to promoter DNA
分子名称: 5'-D(*CP*TP*CP*CP*TP*CP*AP*CP*GP*TP *CP*AP*CP*GP*TP*GP*AP*GP*GP*TP*G)-3', HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TIPA
著者Allan, M.G, Stetefeld, J, Schirmer, T.
登録日2008-07-30
公開日2009-11-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the Transcriptionally Inactive Merr Domain Tipan in Complex with DNA
To be Published
5ZLN
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BU of 5zln by Molmil
Crystal structure of mouse TLR9 in complex with two DNAs (CpG DNA and TCGCCA DNA)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-D(*AP*GP*GP*CP*GP*TP*TP*TP*TP*T)-3'), ...
著者Ishida, H, Ohto, U, Shimizu, T.
登録日2018-03-28
公開日2018-04-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for species-specific activation of mouse Toll-like receptor 9
FEBS Lett., 592, 2018
4M47
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BU of 4m47 by Molmil
structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non-hydrolyzable GTP
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA polymerase beta, MAGNESIUM ION, ...
著者Koag, M.C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-08-06
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
4NM1
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BU of 4nm1 by Molmil
Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-C at N-1 position and G-C at N position
分子名称: 5'-D(*CP*CP*GP*AP*CP*GP*(BGM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
著者Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-11-14
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.415 Å)
主引用文献Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
4NM2
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BU of 4nm2 by Molmil
Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-G at N-1 position and G-C at N position
分子名称: 5'-D(*CP*CP*GP*AP*CP*GP*(BGM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
著者Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-11-14
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.524 Å)
主引用文献Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
4NLK
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BU of 4nlk by Molmil
Structure of human DNA polymerase beta complexed with 8BrG in the template base-paired with incoming non-hydrolyzable CTP
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ...
著者Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-11-14
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.494 Å)
主引用文献Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
4NLN
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BU of 4nln by Molmil
Structure of human DNA polymerase beta complexed with nicked DNA containing a template 8BrG and incoming CTP
分子名称: 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
著者Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-11-14
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.261 Å)
主引用文献Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
4NLZ
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BU of 4nlz by Molmil
Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template 8BrG and incoming GTP
分子名称: 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*G)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
著者Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-11-14
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.683 Å)
主引用文献Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
3BTP
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BU of 3btp by Molmil
Crystal structure of Agrobacterium tumefaciens VirE2 in complex with its chaperone VirE1: a novel fold and implications for DNA binding
分子名称: AMMONIUM ION, DI(HYDROXYETHYL)ETHER, Protein virE1, ...
著者Dym, O, Albeck, S, Unger, T, Elbaum, M, Israel Structural Proteomics Center (ISPC)
登録日2007-12-30
公開日2008-08-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the Agrobacterium virulence complex VirE1-VirE2 reveals a flexible protein that can accommodate different partners.
Proc.Natl.Acad.Sci.Usa, 105, 2008

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件を2024-09-04に公開中

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