PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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5W91	Toxoplasma Gondii CDPK1 in complex with inhibitor LZH118 分子名称: 1-tert-butyl-N~3~-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine, CALCIUM ION, Calmodulin-domain protein kinase 1 著者 El Bakkouri, M, Lovato, D, Loppnau, P, Lin, Y.H, Rutaganaria, F, Lopez, M.S, Shokat, L, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Sibley, D, Hui, R, Walker, J.R, Structural Genomics Consortium (SGC) 登録日 2017-06-22 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Toxoplasma Gondii CDPK1 in complex with inhibitor LZH118 To be published
5WKK	1.55 A resolution structure of MERS 3CL protease in complex with inhibitor GC813 分子名称: (1R,2S)-2-[(N-{[2-(3-chlorophenyl)ethoxy]carbonyl}-L-leucyl)amino]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-[(N-{[2-(3-chlorophenyl)ethoxy]carbonyl}-L-leucyl)amino]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, MAGNESIUM ION, ... 著者 Lovell, S, Battaile, K.P, Mehzabeen, N, Kankanamalage, A.C.G, Kim, Y, Rathnayake, A.D, Chang, K.O, Groutas, W.C. 登録日 2017-07-25 公開日 2018-04-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element. Eur J Med Chem, 150, 2018
5XEV	Crystal Structure of a novel Xaa-Pro dipeptidase from Deinococcus radiodurans 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... 著者 Are, V.N, Kumar, A, Ghosh, B, Makde, R.D. 登録日 2017-04-06 公開日 2017-10-18 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of a novel prolidase from Deinococcus radiodurans identifies new subfamily of bacterial prolidases. Proteins, 85, 2017
5XPT	Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a tetragonal crystal 分子名称: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B 著者 Hara, K, Taharazako, S, Hashimoto, H. 登録日 2017-06-05 公開日 2017-09-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292, 2017
4Z9R	Crystal structure of PfaD from Shewanella oneidensis in complex with NAD+ determined by in-situ diffraction. 分子名称: FLAVIN MONONUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Omega-3 polyunsaturated fatty acid synthase subunit PfaD 著者 Baker, G.E, Race, P.R. 登録日 2015-04-11 公開日 2016-04-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of PfaD from Shewanella oneidensis in complex with NAD+ determined by in-situ diffraction. To Be Published
4ZA0	Structure of Human Enolase 2 in complex with Phosphonoacetohydroxamate 分子名称: Gamma-enolase, MAGNESIUM ION, PHOSPHONOACETOHYDROXAMIC ACID 著者 Leonard, P.G, Maxwell, D, Czako, B, Muller, F.L. 登録日 2015-04-13 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 SF2312 is a natural phosphonate inhibitor of enolase. Nat.Chem.Biol., 12, 2016
4ZCU	Structure of calcium-bound regulatory domain of the human ATP-Mg/Pi carrier in the P2 form 分子名称: CALCIUM ION, Calcium-binding mitochondrial carrier protein SCaMC-1, GLYCEROL, ... 著者 Harborne, S.P.D, Ruprecht, J.J, Kunji, E.R.S. 登録日 2015-04-16 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Calcium-induced conformational changes in the regulatory domain of the human mitochondrial ATP-Mg/Pi carrier. Biochim.Biophys.Acta, 1847, 2015
4ZE0	Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) Y140F mutant complexed with Voriconazole 分子名称: Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE, Voriconazole 著者 Sagatova, A, Keniya, M.V, Wilson, R, Tyndall, J.D.A, Monk, B.C. 登録日 2015-04-20 公開日 2016-03-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase. Sci Rep, 6, 2016
4ZDZ	Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) Y140F mutant complexed with fluconazole 分子名称: 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Sagatova, A, Keniya, M.V, Wilson, R.K, Tyndall, J.D.A, Monk, B.C. 登録日 2015-04-20 公開日 2016-03-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase. Sci Rep, 6, 2016
5XUT	Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (TCTA PAM) 分子名称: 1,2-ETHANEDIOL, DNA (29-MER), DNA (5'-D(*CP*GP*TP*CP*CP*TP*CP*TP*A)-3'), ... 著者 Yamano, T, Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2017-06-26 公開日 2017-08-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Mol. Cell, 67, 2017
4ZFK	Ergothioneine-biosynthetic Ntn hydrolase EgtC with glutamine 分子名称: 1,2-ETHANEDIOL, Amidohydrolase EgtC, GLUTAMINE 著者 Vit, A, Seebeck, F.P, Blankenfeldt, W. 登録日 2015-04-21 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC. Chembiochem, 16, 2015
4ZF7	Crystal structure of ferret interleukin-2 分子名称: DI(HYDROXYETHYL)ETHER, Interleukin 2, PENTAETHYLENE GLYCOL, ... 著者 Ren, B, Newman, J, McKinstry, W.J, Adams, T.E. 登録日 2015-04-21 公開日 2015-11-04 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (1.893 Å) 主引用文献 Structural and functional characterisation of ferret interleukin-2. Dev.Comp.Immunol., 55, 2015
5XQY	Structure of monomeric mutant of REI immunoglobulin light chain variable domain crystallized at pH 8 分子名称: Immunoglobulin kappa variable 1D-33 著者 Mine, S, Nakamura, T, Uegaki, K, Hamada, D. 登録日 2017-06-07 公開日 2017-08-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Heat-induced native dimerization prevents amyloid formation by variable domain from immunoglobulin light-chain REI FEBS J., 284, 2017
5X67	Human thymidylate synthase in complex with dUMP and nolatrexed 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-azanyl-6-methyl-5-pyridin-4-ylsulfanyl-3H-quinazolin-4-one, Thymidylate synthase 著者 Chen, D, Jansson, A, Larsson, A, Nordlund, P. 登録日 2017-02-21 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states. J. Biol. Chem., 292, 2017
4Z19	Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Yersinia pestis with acetylated active site cysteine 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3, GLYCEROL 著者 Nanson, J.D, Forwood, J.K. 登録日 2015-03-27 公開日 2015-05-20 最終更新日 2015-10-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis. Sci Rep, 5, 2015
4Z1M	Bovine F1-ATPase inhibited by three copies of the inhibitor protein IF1 crystallised in the presence of thiophosphate. 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ... 著者 Bason, J.V, Montgomery, M.G, Leslie, A.G.W, Walker, J.E. 登録日 2015-03-27 公開日 2015-05-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 How release of phosphate from mammalian F1-ATPase generates a rotary substep. Proc.Natl.Acad.Sci.USA, 112, 2015
4ZPL	Crystal Structure of Protocadherin Beta 1 EC1-3 分子名称: CALCIUM ION, Protein Pcdhb1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Goodman, K.M, Bahna, F, Shapiro, L. 登録日 2015-05-08 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Molecular Logic of Neuronal Self-Recognition through Protocadherin Domain Interactions. Cell, 163, 2015
5X8C	AMPPCP and TMP bound crystal structure of thymidylate kinase from thermus thermophilus HB8 分子名称: CHLORIDE ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... 著者 Chaudhary, S.K, Jeyakanthan, J, Sekar, K. 登録日 2017-03-02 公開日 2018-03-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structural and functional roles of dynamically correlated residues in thymidylate kinase. Acta Crystallogr D Struct Biol, 74, 2018
4ZRE	Crystal structure of SMG1 F278D mutant 分子名称: CHLORIDE ION, LIP1, secretory lipase (Family 3), ... 著者 Xu, J, Xu, H, Hou, S, Liu, J. 登録日 2015-05-12 公開日 2015-09-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of product-bound SMG1 lipase: active site gating implications. Febs J., 282, 2015
5XAZ	Crystal structure of full length native tylp, a tetr regulator from streptomyces fradiae 分子名称: Gamma-butyrolactone receptor protein 著者 Ray, S, Panjikar, S, Anand, R. 登録日 2017-03-15 公開日 2017-08-02 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Functional insights into the mode of DNA and ligand binding of the TetR family regulator TylP from Streptomyces fradiae J. Biol. Chem., 292, 2017
4Z5Y	The 1.56-angstrom crystal structure of copper(II)-bound PqqB from Pseudomonas Putida 分子名称: COPPER (II) ION, Coenzyme PQQ synthesis protein B, SODIUM ION, ... 著者 Tu, X, Wilmot, C.M. 登録日 2015-04-03 公開日 2016-04-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.561 Å) 主引用文献 Crystal structures reveal metal-binding plasticity at the active site of PqqB To Be Published
5XHO	Crystal structure of Frog M-ferritin E135K mutant 分子名称: CHLORIDE ION, Ferritin, middle subunit, ... 著者 Jagdev, M.K, Vasudevan, D. 登録日 2017-04-21 公開日 2017-08-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Surface charge dependent separation of modified and hybrid ferritin in native PAGE: Impact of lysine 104 Biochim. Biophys. Acta, 1865, 2017
4Z67	The 1.5-angstrom crystal structure of Mn(2+)-bound PqqB from Pseudomonas Putida 分子名称: Coenzyme PQQ synthesis protein B, D-MALATE, MANGANESE (II) ION, ... 著者 Tu, X, Wilmot, C.M. 登録日 2015-04-03 公開日 2016-04-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structures reveal metal-binding plasticity at the active site of PqqB To Be Published
4Z81	Crystal structure of AMA4 DI-DII-EGF1 from Toxoplasma gondii 分子名称: EGF family domain-containing protein, GLYCEROL 著者 Parker, M.L, Boulanger, M.J. 登録日 2015-04-08 公開日 2015-12-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair. Proc.Natl.Acad.Sci.USA, 113, 2016
4ZAU	AZD9291 complex with wild type EGFR 分子名称: Epidermal growth factor receptor, N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide 著者 Squire, C.J, Yosaatmadja, Y, Flanagan, J.U, McKeage, M. 登録日 2015-04-14 公開日 2015-11-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed. J.Struct.Biol., 192, 2015

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