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2TMN
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CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
分子名称: CALCIUM ION, N~2~-phosphono-L-leucinamide, Thermolysin, ...
著者Tronrud, D.E, Monzingo, A.F, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin.
Eur.J.Biochem., 157, 1986
6JJB
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BRD4 in complex with ZZM1
分子名称: 2-methoxy-N-(1-methyl-2-oxidanylidene-benzo[cd]indol-6-yl)benzenesulfonamide, Bromodomain-containing protein 4
著者Xu, J, Chen, Y, Jiang, F, Zhu, J.
登録日2019-02-25
公開日2020-01-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.508 Å)
主引用文献Discovery of Benzo[cd]indol-2(1H)-ones and Pyrrolo[4,3,2-de]quinolin-2(1H)-ones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain with Potential High Efficiency against Acute Gouty Arthritis.
J.Med.Chem., 62, 2019
6JJE
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BU of 6jje by Molmil
Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex (BrU)
分子名称: COBALT HEXAMMINE(III), DNA (5'-D(*GP*GP*CP*(BRU)P*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3'), POTASSIUM ION, ...
著者Zhang, Y.S, Wei, D.G.
登録日2019-02-25
公開日2020-02-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.378 Å)
主引用文献Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex (BrU)
To Be Published
2TPS
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THIAMIN PHOSPHATE SYNTHASE
分子名称: MAGNESIUM ION, PROTEIN (THIAMIN PHOSPHATE SYNTHASE), PYROPHOSPHATE 2-, ...
著者Chiu, H.-J, Reddick, J.J, Begley, T.P, Ealick, S.E.
登録日1999-03-09
公開日1999-03-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structure of thiamin phosphate synthase from Bacillus subtilis at 1.25 A resolution.
Biochemistry, 38, 1999
2UAG
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BU of 2uag by Molmil
UDP-N-ACETYLMURAMOYL-L-ALANINE:D-GLUTAMATE LIGASE
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (UDP-N-ACETYLMURAMOYL-L-ALANINE:D-GLUTAMATE LIGASE), ...
著者Bertrand, J, Fanchon, E, Dideberg, O.
登録日1999-02-23
公開日2000-02-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Determination of the MurD mechanism through crystallographic analysis of enzyme complexes.
J.Mol.Biol., 289, 1999
6JJF
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Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex
分子名称: COBALT HEXAMMINE(III), DNA (5'-D(*GP*GP*CP*TP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3'), POTASSIUM ION, ...
著者Zhang, Y.S, EI Omari, K, Duman, R, Wagner, A, Parkinson, G.N, Wei, D.G.
登録日2019-02-25
公開日2020-02-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020
1IN8
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BU of 1in8 by Molmil
THERMOTOGA MARITIMA RUVB T158V
分子名称: ADENOSINE-5'-DIPHOSPHATE, HOLLIDAY JUNCTION DNA HELICASE RUVB
著者Putnam, C.D, Clancy, S.B, Tsuruta, H, Wetmur, J.G, Tainer, J.A.
登録日2001-05-12
公開日2001-08-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and mechanism of the RuvB Holliday junction branch migration motor.
J.Mol.Biol., 311, 2001
6JJT
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Crystal structure of an enzyme from Penicillium herquei in condition1
分子名称: CITRIC ACID, DI(HYDROXYETHYL)ETHER, PhnH
著者Fen, Y, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2019-02-26
公開日2020-01-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Crystal structure and proposed mechanism of an enantioselective hydroalkoxylation enzyme from Penicillium herquei.
Biochem.Biophys.Res.Commun., 516, 2019
2RD3
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BU of 2rd3 by Molmil
Crystal structure of TenA homologue (HP1287) from Helicobacter pylori
分子名称: Transcriptional regulator
著者Barison, N, Cendron, L, Trento, A, Angelini, A, Zanotti, G.
登録日2007-09-21
公開日2008-09-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structural and functional characterization of HP1287 from Helicobacter pylori demonstrates it is a TenA homologue
To be Published
1IDF
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ISOCITRATE DEHYDROGENASE K230M MUTANT APO ENZYME
分子名称: ISOCITRATE DEHYDROGENASE
著者Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L.
登録日1995-01-18
公開日1996-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
8HHH
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The bacterial divisome protein complex FtsB-FtsL-FtsQ
分子名称: Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ
著者Nguyen, V.H.T, Chen, X.
登録日2022-11-16
公開日2023-04-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome.
Nat Commun, 14, 2023
8HHF
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The bacterial divisome protein complex FtsB-FtsL-FtsQ
分子名称: Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ
著者Nguyen, V.H.T, Chen, X.
登録日2022-11-16
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome.
Nat Commun, 14, 2023
2TMD
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BU of 2tmd by Molmil
CORRELATION OF X-RAY DEDUCED AND EXPERIMENTAL AMINO ACID SEQUENCES OF TRIMETHYLAMINE DEHYDROGENASE
分子名称: ADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ...
著者Mathews, F.S, Lim, L.W, White, S.
登録日1993-10-15
公開日1994-01-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Correlation of x-ray deduced and experimental amino acid sequences of trimethylamine dehydrogenase.
J.Biol.Chem., 267, 1992
8H9H
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BU of 8h9h by Molmil
Crystal structure of ZBTB7A in complex with GACCC-containing sequence
分子名称: DNA (5'-D(*TP*AP*AP*GP*GP*AP*CP*CP*CP*AP*GP*AP*T)-3'), DNA (5'-D(P*AP*AP*TP*CP*TP*GP*GP*GP*TP*CP*CP*TP*T)-3'), ZINC ION, ...
著者Yang, Y.
登録日2022-10-25
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献ZBTB7A regulates primed-to-naive transition of pluripotent stem cells via recognition of the PNT-associated sequence by zinc fingers 1-2 and recognition of gamma-globin -200 gene element by zinc fingers 1-4.
Febs J., 290, 2023
8H66
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BU of 8h66 by Molmil
Crystal structure of human GCN5 histone acetyltransferase domain bound with propionyl-CoA
分子名称: Histone acetyltransferase KAT2A, propionyl Coenzyme A
著者Li, N, Tao, Y.J, Guo, Y.R.
登録日2022-10-15
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications.
Res, 6, 2023
6JKP
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BU of 6jkp by Molmil
Crystal structure of sulfoacetaldehyde reductase from Bifidobacterium kashiwanohense in complex with NAD+
分子名称: Methanol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
著者Zhou, Y, Xu, T, Lin, L, Zhang, Y, Yuchi, Z.
登録日2019-03-01
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.008 Å)
主引用文献Identification and characterization of a new sulfoacetaldehyde reductase from the human gut bacteriumBifidobacterium kashiwanohense.
Biosci.Rep., 39, 2019
8HKJ
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BU of 8hkj by Molmil
Crystal structure of the CYP102A5 haem Domain isolated from Bacillus cereus
分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, PALMITIC ACID, PROTOPORPHYRIN IX CONTAINING FE
著者Stanfield, J.K, Onoda, H, Sugimoto, H, Shoji, O.
登録日2022-11-27
公開日2023-04-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Investigating the applicability of the CYP102A1-decoy-molecule system to other members of the CYP102A subfamily.
J.Inorg.Biochem., 245, 2023
2RLL
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BU of 2rll by Molmil
CCR5 Nt(7-15)
分子名称: 9-mer from C-C chemokine receptor type 5
著者Bewley, C.A, Lam, S.N.
登録日2007-07-21
公開日2007-09-25
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4
Science, 317, 2007
2RLW
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BU of 2rlw by Molmil
Three-Dimensional Structure of the two Peptides that Constitute the Two-Peptide Bacteriocin Plantaracin EF
分子名称: PlnF
著者Fimland, N, Rogne, P, Fimland, G, Nissen-Meyer, J, Kristiansen, P.
登録日2007-08-27
公開日2008-07-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of the two peptides that constitute the two-peptide bacteriocin plantaricin EF
Biochim.Biophys.Acta, 1784, 2008
6JJO
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Crystal structure of the DegP dodecamer with a modulator
分子名称: Periplasmic serine endoprotease DegP, TMB-CYRKL modulator
著者Cho, H, Choi, Y, Lee, H.H, Kim, S.
登録日2019-02-26
公開日2020-09-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.157 Å)
主引用文献Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020
8GXD
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BU of 8gxd by Molmil
L-LEUCINE DEHYDROGENASE FROM EXIGUOBACTERIUM SIBIRICUM
分子名称: CALCIUM ION, GLYCEROL, Glu/Leu/Phe/Val dehydrogenase
著者Mu, X, Nie, Y, Wu, T, Wang, Y, Zhang, N, Yin, D, Xu, Y.
登録日2022-09-19
公開日2023-04-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Reshaping Substrate-Binding Pocket of Leucine Dehydrogenase for Bidirectionally Accessing Structurally Diverse Substrates
Acs Catalysis, 13, 2023
2RMC
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BU of 2rmc by Molmil
Crystal structure of murine cyclophilin C complexed with immunosuppressive drug cyclosporin A
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C
著者Ke, H, Zhao, Y, Luo, F, Weissman, I, Friedman, J.
登録日1994-01-07
公開日1995-02-14
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal Structure of Murine Cyclophilin C Complexed with Immunosuppressive Drug Cyclosporin A
Proc.Natl.Acad.Sci.USA, 90, 1993
6Q19
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Inferred intermediate (I-6) of the human antibody lineage 652
分子名称: Fab heavy chain, Fab lambda chain
著者McCarthy, K.R, Harrison, S.C.
登録日2019-08-03
公開日2019-12-18
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6JKO
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Crystal structure of sulfoacetaldehyde reductase from Bifidobacterium kashiwanohense
分子名称: Methanol dehydrogenase, ZINC ION
著者Zhou, Y, Xu, T, Lin, L, Zhang, Y, Yuchi, Z.
登録日2019-03-01
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification and characterization of a new sulfoacetaldehyde reductase from the human gut bacteriumBifidobacterium kashiwanohense.
Biosci.Rep., 39, 2019
6Q1J
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Antibody H2227 from the human antibody lineage 652
分子名称: Fab heavy chain, Fab lambda light chain
著者McCarthy, K.R, Harrison, S.C, Raymond, D.D.
登録日2019-08-05
公開日2019-12-18
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019

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