4OHZ
 
 | | bound to ssRNA tetranucleotide GAAA, ADP, and Mg2+ | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... | | 著者 | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | | 登録日 | 2014-01-18 | | 公開日 | 2014-05-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
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6BMG
 | | Structure of Recombinant Dwarf Sperm Whale Myoglobin (Oxy) | | 分子名称: | ACETATE ION, CADMIUM ION, Myoglobin, ... | | 著者 | Samuel, P.P, Miller, M.D, Xu, W, Alvarado, S, Phillips Jr, G.N, Olson, J.S. | | 登録日 | 2017-11-14 | | 公開日 | 2017-11-29 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Structure of Recombinant Dwarf Sperm Whale Myoglobin (Oxy)
To Be Published
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4XAY
 | | Cycles of destabilization and repair underlie evolutionary transitions in enzymes | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-R8, ... | | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | | 登録日 | 2014-12-16 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat.Chem.Biol., 12, 2016
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1PCL
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3HEZ
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2A2G
 | | THE CRYSTAL STRUCTURES OF A2U-GLOBULIN AND ITS COMPLEX WITH A HYALINE DROPLET INDUCER. | | 分子名称: | D-LIMONENE 1,2-EPOXIDE, PROTEIN (ALPHA-2U-GLOBULIN) | | 著者 | Chaudhuri, B.N, Kleywegt, G.J, Jones, T.A. | | 登録日 | 1998-11-19 | | 公開日 | 1999-08-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The structures of alpha 2u-globulin and its complex with a hyaline droplet inducer.
Acta Crystallogr.,Sect.D, 55, 1999
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2A2U
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2Q66
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4PSR
 | | Crystal Structure of alpha-L-fucosidase from Fusarium graminearum in the open form in complex with L-fucose | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-fucosidase GH29, ... | | 著者 | Cao, H, Walton, J, Brumm, P, Phillips Jr, G.N. | | 登録日 | 2014-03-07 | | 公開日 | 2014-03-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Structure and Substrate Specificity of a Eukaryotic Fucosidase from Fusarium graminearum.
J.Biol.Chem., 289, 2014
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3HI4
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4CVA
 | | MPS1 kinase with 3-aminopyridin-2-one inhibitors | | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, DUAL SPECIFICITY PROTEIN KINASE TTK, ... | | 著者 | Fearon, D, Bavetsias, V, Bayliss, R, Schmitt, J, Westwood, I.M, vanMontfort, R.L.M, Jones, K. | | 登録日 | 2014-03-24 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Protein Kinase Selectivity of a 3-Aminopyridin-2- One Based Fragment Library, Identification of 3-Amino-5-(Pyridin-4-Yl)Pyridin-2(1H)-One as a Novel Scaffold for Mps1 Inhibition
To be Published
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6B1Q
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1SZ1
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6MUR
 | | Cryo-EM structure of Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system | | 分子名称: | RNA (27-MER), RNA (5'-R(P*GP*CP*AP*AP*AP*CP*CP*GP*CP*CP*UP*CP*UP*GP*CP*CP*CP*GP*C)-3'), Uncharacterized protein, ... | | 著者 | Jia, N, Wang, C, Eng, E.T, Patel, D.J. | | 登録日 | 2018-10-23 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
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1EBF
 | | HOMOSERINE DEHYDROGENASE FROM S. CEREVISIAE COMPLEX WITH NAD+ | | 分子名称: | HOMOSERINE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION | | 著者 | DeLaBarre, B, Thompson, P.R, Wright, G.D, Berghuis, A.M. | | 登録日 | 2000-01-24 | | 公開日 | 2000-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases.
Nat.Struct.Biol., 7, 2000
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4OI1
 | | Clp1 bound to ssRNA dinucleotide GC, ADP, AlF4-, and Mg2+(transition state, data set II) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... | | 著者 | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | | 登録日 | 2014-01-18 | | 公開日 | 2014-05-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
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4OI2
 | | C. Elegans Clp1 and ADP and Mg2+ (turnover state) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... | | 著者 | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | | 登録日 | 2014-01-18 | | 公開日 | 2014-05-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
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1Q53
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1L8B
 | | Cocrystal Structure of the Messenger RNA 5' Cap-binding Protein (eIF4E) bound to 7-methylGpppG | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | | 著者 | Niedzwiecka, A, Marcotrigiano, J, Stepinski, J, Jankowska-Anyszka, M, Wyslouch-Cieszynska, A, Dadlez, M, Gingras, A.-C, Mak, P, Darzynkiewicz, E, Sonenberg, N. | | 登録日 | 2002-03-19 | | 公開日 | 2002-06-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins.
J.Mol.Biol., 319, 2002
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4DU3
 | | RB69 DNA Polymerase Ternary Complex with dDTP Opposite dT with 3-Deaza-adenine at the N-1 Position of Template Strand | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... | | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | | 登録日 | 2012-02-21 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Probing minor groove hydrogen bonding interactions between RB69 DNA polymerase and DNA.
Biochemistry, 51, 2012
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1UV0
 | | Pancreatitis-associated protein 1 from human | | 分子名称: | PANCREATITIS-ASSOCIATED PROTEIN 1, ZINC ION | | 著者 | Abergel, C, Shepard, W, Christal, L. | | 登録日 | 2004-01-12 | | 公開日 | 2004-01-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystallization and preliminary crystallographic study of HIP/PAP, a human C-lectin overexpressed in primary liver cancers.
Acta Crystallogr.,Sect.D, 55, 1999
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1GKP
 | | D-Hydantoinase (Dihydropyrimidinase) from Thermus sp. in space group C2221 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HYDANTOINASE, SULFATE ION, ... | | 著者 | Abendroth, J, Niefind, K, Schomburg, D. | | 登録日 | 2001-08-20 | | 公開日 | 2002-06-27 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.295 Å) | | 主引用文献 | X-Ray Structure of a Dihydropyrimidinase from Thermus Sp. At 1.3 A Resolution
J.Mol.Biol., 320, 2002
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1GDH
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8F2P
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8EGU
 | | Branched chain ketoacid dehydrogenase kinase complexes | | 分子名称: | (2~{S})-3-methyl-2-[pentanoyl-[[4-[2-(2~{H}-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, ... | | 著者 | Liu, S. | | 登録日 | 2022-09-13 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.923 Å) | | 主引用文献 | Structural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitors.
J.Biol.Chem., 299, 2023
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