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2NDP
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BU of 2ndp by Molmil
Structure of DNA-binding HU protein from micoplasma Mycoplasma gallisepticum
分子名称: Histone-like DNA-binding superfamily protein
著者Altukhov, D.A, Talyzina, A.A, Agapova, Y.K, Vlaskina, A.V, Korzhenevskiy, D.A, Bocharov, E.V, Rakitina, T.V, Timofeev, V.I, Popov, V.O.
登録日2016-09-13
公開日2016-11-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Enhanced conformational flexibility of the histone-like (HU) protein from Mycoplasma gallisepticum.
J.Biomol.Struct.Dyn., 36, 2018
7TQN
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BU of 7tqn by Molmil
Structure of human TREX1
分子名称: Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TQO
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Structure of human TREX1
分子名称: Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TQP
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BU of 7tqp by Molmil
Structure of human TREX1
分子名称: SULFATE ION, Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
5WX8
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BU of 5wx8 by Molmil
Human herpesvirus 6A immediate early protein 2 C-terminal domain
分子名称: Immediate-early protein 2
著者Nishimura, M, Wang, J, Wakata, A, Sakamoto, K, Mori, Y.
登録日2017-01-06
公開日2017-08-02
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the DNA-Binding Domain of Human Herpesvirus 6A Immediate Early Protein 2.
J. Virol., 91, 2017
6Z6E
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BU of 6z6e by Molmil
Crystal structure of the HK97 bacteriophage small terminase
分子名称: IODIDE ION, Terminase small subunit
著者Fung, H.K.H, Chechik, M, Baumann, C.G, Antson, A.A.
登録日2020-05-28
公開日2021-06-09
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system.
Nucleic Acids Res., 50, 2022
3ON0
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BU of 3on0 by Molmil
Crystal structure of the pED208 TraM-sbmA complex
分子名称: Protein traM, sbmA
著者Wong, J.J.W, Lu, J, Edwards, R.A, Frost, L.S, Mark Glover, J.N.
登録日2010-08-27
公開日2011-05-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.874 Å)
主引用文献Structural basis of cooperative DNA recognition by the plasmid conjugation factor, TraM.
Nucleic Acids Res., 39, 2011
2LF7
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BU of 2lf7 by Molmil
Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to Q436
分子名称: Transcription factor ETV6
著者Coyne III, H, Green, S.M, Graves, B.J, Mcintosh, L.P.
登録日2011-06-28
公開日2012-05-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain.
J.Mol.Biol., 421, 2012
2ME0
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BU of 2me0 by Molmil
NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens solved in the presence of the DNA sequence CGACTAATTAGTCG
分子名称: Homeobox protein GBX-1
著者Proudfoot, A, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL)
登録日2013-09-20
公開日2013-10-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens solved in the presence of the DNA sequence CGACTAATTAGTCG
To be Published
3IL2
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BU of 3il2 by Molmil
Crystal structure of a Rex-family repressor R90D mutant/DNA complex from Thermus aquaticus
分子名称: Redox-sensing transcriptional repressor rex, Rex operator DNA
著者McLaughlin, K.J, Kielkopf, C.L.
登録日2009-08-06
公開日2010-06-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural basis for NADH/NAD+ redox sensing by a Rex family repressor.
Mol.Cell, 38, 2010
5FW1
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BU of 5fw1 by Molmil
Crystal structure of SpyCas9 variant VQR bound to sgRNA and TGAG PAM target DNA
分子名称: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ...
著者Anders, C, Bargsten, K, Jinek, M.
登録日2016-02-11
公開日2016-04-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Mol.Cell, 61, 2016
7B4G
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BU of 7b4g by Molmil
Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R282W mutant bound to DNA: R282W-MQ (II)
分子名称: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DI(HYDROXYETHYL)ETHER, ...
著者Degtjarik, O, Rozenberg, H, Shakked, Z.
登録日2020-12-02
公開日2021-12-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ).
Nat Commun, 12, 2021
7UJN
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BU of 7ujn by Molmil
Structure of Human SAMHD1 with Non-Hydrolysable dGTP Analog
分子名称: 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
著者Huynh, K.W, Ammirati, M, Han, S.
登録日2022-03-31
公開日2022-07-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation and ssDNA binding kinetics.
Nucleic Acids Res., 50, 2022
5FW3
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BU of 5fw3 by Molmil
Crystal structure of SpCas9 variant VRER bound to sgRNA and TGCG PAM target DNA
分子名称: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ...
著者Anders, C, Bargsten, K, Jinek, M.
登録日2016-02-11
公開日2016-06-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Mol.Cell, 61, 2016
5FW2
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BU of 5fw2 by Molmil
Crystal structure of SpCas9 variant EQR bound to sgRNA and TGAG PAM target DNA
分子名称: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ...
著者Anders, C, Bargsten, K, Jinek, M.
登録日2016-02-11
公開日2016-06-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.676 Å)
主引用文献Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Mol.Cell, 61, 2016
3IKT
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BU of 3ikt by Molmil
Crystal structure of a Rex-family repressor/DNA/NAD+ complex from Thermus aquaticus
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Redox-sensing transcriptional repressor rex, Rex operator DNA
著者McLaughlin, K.J, Kielkopf, C.L.
登録日2009-08-06
公開日2010-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural basis for NADH/NAD+ redox sensing by a Rex family repressor.
Mol.Cell, 38, 2010
4ZN1
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BU of 4zn1 by Molmil
Crystal Structure of MjSpt4:Spt5 complex conformation A
分子名称: Transcription elongation factor Spt4, Transcription elongation factor Spt5, ZINC ION
著者Guo, G.R, Zhou, H.H, Gao, Y.X, Zhu, Z.L, Niu, L.W, Teng, M.K.
登録日2015-05-04
公開日2016-03-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and biochemical insights into the DNA-binding mode of MjSpt4p:Spt5 complex at the exit tunnel of RNAPII
J.Struct.Biol., 192, 2015
2I9T
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BU of 2i9t by Molmil
Structure of NF-kB p65-p50 heterodimer bound to PRDII element of B-interferon promoter
分子名称: 5'-D(*AP*GP*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*CP*TP*G)-3', 5'-D(*CP*AP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*AP*CP*T)-3', Nuclear factor NF-kappa-B p105 subunit, ...
著者Escalante, C.R, Shen, L, Thanos, D, Aggarwal, A.K.
登録日2006-09-06
公開日2007-02-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter
Structure, 10, 2002
3HIF
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BU of 3hif by Molmil
The crystal structure of apo wild type CAP at 3.6 A resolution.
分子名称: Catabolite gene activator
著者Steitz, T.A, Sharma, H, Wang, J, Kong, J, Yu, S.
登録日2009-05-19
公開日2009-09-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.59 Å)
主引用文献Structure of apo-CAP reveals that large conformational changes are necessary for DNA binding.
Proc.Natl.Acad.Sci.USA, 106, 2009
7O7B
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BU of 7o7b by Molmil
Solution NMR Structure of the Neh1 Domain of Human Nuclear factor erythroid 2-related factor 2 (NRF2)
分子名称: Isoform 3 of Nuclear factor erythroid 2-related factor 2
著者Brueschweiler, S.
登録日2021-04-13
公開日2021-09-29
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A Step toward NRF2-DNA Interaction Inhibitors by Fragment-Based NMR Methods.
Chemmedchem, 16, 2021
8PVT
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BU of 8pvt by Molmil
Manganese-dependent transcriptional repressor DR2539 complexed with cadmium (SAD 7 keV)
分子名称: CADMIUM ION, Iron dependent repressor, putative
著者Mota, C, De Sanctis, D.
登録日2023-07-18
公開日2024-05-08
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Metal ion activation and DNA recognition by the Deinococcus radiodurans manganese sensor DR2539.
Febs J., 291, 2024
8PVZ
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BU of 8pvz by Molmil
Manganese-dependent transcriptional repressor DR2539 complexed with cadmium
分子名称: CADMIUM ION, Iron dependent repressor, putative
著者Mota, C, De Sanctis, D.
登録日2023-07-18
公開日2024-05-08
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Metal ion activation and DNA recognition by the Deinococcus radiodurans manganese sensor DR2539.
Febs J., 291, 2024
6Z6D
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BU of 6z6d by Molmil
Crystal structure of the HK97 bacteriophage large terminase
分子名称: BROMIDE ION, Terminase large subunit
著者Fung, H.K.H, Chechik, M, Baumann, C.G, Antson, A.A.
登録日2020-05-28
公開日2021-06-09
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system.
Nucleic Acids Res., 50, 2022
2D1H
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BU of 2d1h by Molmil
Crystal structure of ST1889 protein from thermoacidophilic archaeon Sulfolobus tokodaii
分子名称: 109aa long hypothetical transcriptional regulator
著者Shinkai, A, Sekine, S, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-08-22
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The putative DNA-binding protein Sto12a from the thermoacidophilic archaeon Sulfolobus tokodaii contains intrachain and interchain disulfide bonds.
J.Mol.Biol., 372, 2007
7UFI
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VchTnsC AAA+ ATPase with DNA, single heptamer
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*TP*CP*CP*AP*GP*TP*AP*CP*AP*GP*CP*GP*CP*GP*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*AP*GP*CP*CP*GP*CP*GP*CP*TP*GP*TP*AP*CP*TP*GP*GP*AP*G)-3'), ...
著者Fernandez, I.S, Sternberg, S.H.
登録日2022-03-22
公開日2022-06-08
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Selective TnsC recruitment enhances the fidelity of RNA-guided transposition.
Nature, 609, 2022

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