PDB: 2005 件ウェブページステータス検索Chemie searchBIRD

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1K83	Crystal Structure of Yeast RNA Polymerase II Complexed with the Inhibitor Alpha Amanitin 分子名称: ALPHA AMANITIN, DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, ... 著者 Bushnell, D.A, Cramer, P, Kornberg, R.D. 登録日 2001-10-22 公開日 2002-02-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Basis of Transcription: Alpha-Amanitin-RNA Polymerase II Cocrystal at 2.8 A Resolution. Proc.Natl.Acad.Sci.USA, 99, 2002
8BYQ	RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. 登録日 2022-12-14 公開日 2023-05-03 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
4V1O	Architecture of the RNA polymerase II-Mediator core transcription initiation complex 分子名称: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... 著者 Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. 登録日 2014-09-29 公開日 2015-02-04 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (9.7 Å) 主引用文献 Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
4V1N	Architecture of the RNA polymerase II-Mediator core transcription initiation complex 分子名称: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... 著者 Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. 登録日 2014-09-29 公開日 2015-02-04 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.8 Å) 主引用文献 Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
1Y1W	Complete RNA Polymerase II elongation complex 分子名称: 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*AP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ... 著者 Cramer, P, Kettenberger, H, Armache, K.-J. 登録日 2004-11-19 公開日 2005-01-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS Mol.Cell, 16, 2004
1Y1V	Refined RNA Polymerase II-TFIIS complex 分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... 著者 Kettenberger, H, Armache, K.-J, Cramer, P. 登録日 2004-11-19 公開日 2004-12-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS. Mol.Cell, 16, 2004
4X2B	K20A RNA dependent RNA polymerase mutant from Foot-and-Mouth disease Virus complexed with an RNA 分子名称: MAGNESIUM ION, RNA dependent RNA polymerase, RNA primer, ... 著者 Verdaguer, N, Ferrer-Orta, C. 登録日 2014-11-26 公開日 2015-05-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. J.Virol., 89, 2015
5IY8	Human holo-PIC in the initial transcribing state 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. 登録日 2016-03-24 公開日 2016-05-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (7.9 Å) 主引用文献 Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
5IY6	Human holo-PIC in the closed state 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. 登録日 2016-03-24 公開日 2016-05-18 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (7.2 Å) 主引用文献 Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
5IY9	Human holo-PIC in the initial transcribing state (no IIS) 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. 登録日 2016-03-24 公開日 2016-05-18 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
5IY7	Human holo-PIC in the open state 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. 登録日 2016-03-24 公開日 2016-05-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (8.6 Å) 主引用文献 Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
8BZ1	RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. 登録日 2022-12-14 公開日 2023-05-03 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
6NUR	SARS-Coronavirus NSP12 bound to NSP7 and NSP8 co-factors 分子名称: NSP12, NSP7, NSP8, ... 著者 Kirchdoerfer, R.N, Ward, A.B. 登録日 2019-02-01 公開日 2019-05-29 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors. Nat Commun, 10, 2019
2IJN	Isothiazoles as active-site inhibitors of HCV NS5B polymerase 分子名称: (2R,3R)-3-{[3,5-BIS(TRIFLUOROMETHYL)PHENYL]AMINO}-2-CYANO-3-THIOXOPROPANAMIDE, RNA polymerase NS5B 著者 Yan, S, Yao, N. 登録日 2006-09-29 公開日 2006-11-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Isothiazoles as active-site inhibitors of HCV NS5B polymerase Bioorg.Med.Chem.Lett., 17, 2007
5IYA	Human core-PIC in the closed state 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. 登録日 2016-03-24 公開日 2016-05-18 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (5.4 Å) 主引用文献 Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
5IYC	Human core-PIC in the initial transcribing state 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. 登録日 2016-03-24 公開日 2016-05-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
5IYB	Human core-PIC in the open state 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. 登録日 2016-03-24 公開日 2016-05-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
5IYD	Human core-PIC in the initial transcribing state (no IIS) 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. 登録日 2016-03-24 公開日 2016-05-18 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
7YCX	The structure of INTAC-PEC complex 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... 著者 Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. 登録日 2022-07-02 公開日 2023-03-15 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (4.18 Å) 主引用文献 Structural basis of INTAC-regulated transcription. Protein Cell, 14, 2023
4V1M	Architecture of the RNA polymerase II-Mediator core transcription initiation complex 分子名称: 5'-D(*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-D(*CP*CP*AP*GP*GP*AP)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP*TP*TP*CP *CP*BRUP*GP*GP*TP*C)-3', ... 著者 Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. 登録日 2014-09-29 公開日 2015-02-04 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
4X67	Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions. 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, L, Chong, J, Wang, D. 登録日 2014-12-07 公開日 2015-02-04 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions. Proc.Natl.Acad.Sci.USA, 112, 2015
4WZM	Mutant K18E of RNA dependent RNA polymerase from Foot-and-Mouth Disease Virus complexed with RNA 分子名称: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... 著者 Verdaguer, N, Ferrer-Orta, C, de la Higuera, N. 登録日 2014-11-20 公開日 2015-05-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. J.Virol., 89, 2015
8HE5	RNA polymerase II elongation complex bound with Rad26 and Elf1, stalled at SHL(-3.5) of the nucleosome 分子名称: DNA (198-MER), DNA repair protein, DNA-directed RNA polymerase subunit, ... 著者 Osumi, K, Kujirai, T, Ehara, H, Kinoshita, C, Saotome, M, Kagawa, W, Sekine, S, Takizawa, Y, Kurumizaka, H. 登録日 2022-11-07 公開日 2023-07-05 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (6.95 Å) 主引用文献 Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome. J.Mol.Biol., 435, 2023
8H0W	RNA polymerase II transcribing a chromatosome (type II) 分子名称: DNA (261-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Hirano, R, Ehara, H, Tomoya, K, Takizawa, Y, Sekine, S, Kurumizaka, H. 登録日 2022-09-30 公開日 2022-12-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1. Nat Commun, 13, 2022
8H0V	RNA polymerase II transcribing a chromatosome (type I) 分子名称: DNA (261-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Hirano, R, Ehara, H, Tomoya, K, Takizawa, Y, Sekine, S, Kurumizaka, H. 登録日 2022-09-30 公開日 2022-12-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1. Nat Commun, 13, 2022

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