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7M53
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B6 Fab fragment bound to the SARS-CoV/SARS-CoV-2 spike stem helix peptide
分子名称: B6 antigen-binding (Fab) fragment heavy chain, B6 antigen-binding (Fab) fragment light chain, GLYCEROL, ...
著者Sauer, M.M, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-03-22
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis for broad coronavirus neutralization.
Nat.Struct.Mol.Biol., 28, 2021
7M71
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SARS-CoV-2 Spike:5A6 Fab complex I focused refinement
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 5A6 Fab heavy chain, Antibody 5A6 Fab light chain, ...
著者Asarnow, D, Cheng, Y.
登録日2021-03-26
公開日2021-05-26
最終更新日2021-06-23
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Cell, 184, 2021
7M7B
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SARS-CoV-2 Spike:Fab 3D11 complex focused refinement
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 3D11 heavy chain, Antibody Fab 3D11 light chain, ...
著者Asarnow, D, Cheng, Y.
登録日2021-03-27
公開日2021-05-26
最終更新日2021-06-23
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Cell, 184, 2021
7MFU
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BU of 7mfu by Molmil
Crystal structure of synthetic nanobody (Sb14+Sb68) complexes with SARS-CoV-2 receptor binding domain
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Spike protein S1, ...
著者Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H.
登録日2021-04-11
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.
J.Biol.Chem., 297, 2021
7N8I
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BU of 7n8i by Molmil
SARS-CoV-2 S (B.1.429 / epsilon variant) + S2M11 + S2L20 (Local Refinement of the NTD/S2L20)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab Heavy Chain Variable Region, S2L20 Fab Light Chain Variable Region, ...
著者McCallum, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2021-06-14
公開日2021-07-14
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern.
Science, 373, 2021
7N8H
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BU of 7n8h by Molmil
SARS-CoV-2 S (B.1.429 / epsilon variant) + S2M11 + S2L20 Global Refinement
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-06-14
公開日2021-07-14
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern.
Science, 373, 2021
7N9A
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BU of 7n9a by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS RBD with NB21
分子名称: Nanobody Nb21, Spike protein S1
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes
To Be Published
7N9C
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BU of 7n9c by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB95
分子名称: Nanobody NB95, Spike glycoprotein
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7N9E
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BU of 7n9e by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB34
分子名称: Nb34 nanobody, Spike glycoprotein
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7N64
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BU of 7n64 by Molmil
SARS-CoV-2 Spike (2P) in complex with G32R7 Fab (RBD and NTD local reconstruction)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G32R7 Fab heavy chain, ...
著者Windsor, I.W, Jenni, S, Tong, P, Gautam, A.K, Wesemann, D.R, Harrison, S.C.
登録日2021-06-07
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike.
Biorxiv, 2021
7N9B
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BU of 7n9b by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB21
分子名称: NB21 Nanobody, Spike glycoprotein
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7N62
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BU of 7n62 by Molmil
SARS-CoV-2 Spike (2P) in complex with C12C9 Fab (NTD local reconstruction)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C12C9 Fab heavy chain, C12C9 Fab light chain, ...
著者Windsor, I.W, Jenni, S, Bajic, G, Tong, P, Gautam, A.K, Wesemann, D.R, Harrison, S.C.
登録日2021-06-07
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike.
Biorxiv, 2021
7N3I
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BU of 7n3i by Molmil
Crystal structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment C098
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C098 Fab heavy chain, C098 Fab light chain, ...
著者Flyak, A.I, Bjorkman, P.J, Barnes, C.O.
登録日2021-06-01
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7N9T
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BU of 7n9t by Molmil
CryoEM structure of SARS-CoV-2 Spike in complex with Nb17
分子名称: Nanobody Nb17, Spike glycoprotein
著者Huang, W, Taylor, D.
登録日2021-06-18
公開日2021-08-11
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7MY8
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BU of 7my8 by Molmil
Fusion Peptide of SARS-CoV-2 Spike Rearranges into a Wedge Inserted in Bilayered Micelles
分子名称: Spike protein S2
著者Koppisetti, R.K, Fulcher, Y.G, Van Doren, S.R.
登録日2021-05-20
公開日2021-08-18
最終更新日2021-09-08
実験手法SOLUTION NMR
主引用文献Fusion Peptide of SARS-CoV-2 Spike Rearranges into a Wedge Inserted in Bilayered Micelles.
J.Am.Chem.Soc., 143, 2021
7N4J
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BU of 7n4j by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2173.
分子名称: Spike protein S1, WRAIR-2173 antibody Fab heavy chain, WRAIR-2173 antibody Fab light chain, ...
著者Sankhala, R.S, Joyce, M.G.
登録日2021-06-04
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.207 Å)
主引用文献Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations.
Nat.Immunol., 22, 2021
7N4I
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BU of 7n4i by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2057.
分子名称: GLYCEROL, Spike protein S1, WRAIR-2057 Antibody Fab Heavy Chain, ...
著者Sankhala, R.S, Joyce, M.G.
登録日2021-06-04
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.284 Å)
主引用文献Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations.
Nat.Immunol., 22, 2021
7MZG
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BU of 7mzg by Molmil
SARS-CoV-2 receptor binding domain bound to Fab PDI 42
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, PDI 42 heavy chain, ...
著者Pymm, P, Chan, L.J, Dietrich, M.H, Tan, L.L, Tham, W.H.
登録日2021-05-24
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MZK
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BU of 7mzk by Molmil
SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 and Fab PDI 96
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ...
著者Pymm, P, Dietrich, M.H, Tan, L.L, Chan, L.J, Tham, W.H.
登録日2021-05-24
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MTD
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BU of 7mtd by Molmil
Structure of aged SARS-CoV-2 S2P spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Tsybovsky, Y, Olia, A.S, Kwong, P.D.
登録日2021-05-13
公開日2021-09-15
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.
J.Biol.Chem., 297, 2021
7MTC
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BU of 7mtc by Molmil
Structure of freshly purified SARS-CoV-2 S2P spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Tsybovsky, Y, Olia, A.S, Kwong, P.D.
登録日2021-05-13
公開日2021-09-15
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.
J.Biol.Chem., 297, 2021
7MTE
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BU of 7mte by Molmil
Structure of SARS-CoV-2 S2P spike at pH 7.4 refolded by low-pH treatment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Tsybovsky, Y, Olia, A.S, Kwong, P.D.
登録日2021-05-13
公開日2021-09-15
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.
J.Biol.Chem., 297, 2021
7NKT
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BU of 7nkt by Molmil
RBD domain of SARS-CoV2 in complex with neutralizing nanobody NM1226
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ...
著者Ostertag, E, Zocher, G, Stehle, T.
登録日2021-02-18
公開日2021-05-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献NeutrobodyPlex-monitoring SARS-CoV-2 neutralizing immune responses using nanobodies.
Embo Rep., 22, 2021
7MZH
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BU of 7mzh by Molmil
SARS-CoV-2 receptor binding domain bound to Fab WCSL 119
分子名称: Spike protein S1, WCSL 119 heavy chain, WCSL 119 light chain, ...
著者Pymm, P, Tan, L.L, Dietrich, M.H, Chan, L.J, Tham, W.H.
登録日2021-05-24
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MZJ
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BU of 7mzj by Molmil
SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 and Fab PDI 93
分子名称: GLYCEROL, PDI 93 heavy chain, PDI 93 light chain, ...
著者Pymm, P, Dietrich, M.H, Tan, L.L, Chan, L.J, Tham, W.H.
登録日2021-05-24
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021

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件を2024-07-24に公開中

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