3CFL
 
 | | Crystal structure of the complex formed between C-lobe of bovine lactoferrin and 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine at 2.25 A resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine, CARBONATE ION, ... | | 著者 | Mir, R, Vikram, G, Singh, N, Sharma, S, Kaur, P, Singh, T.P. | | 登録日 | 2008-03-04 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structure of the complex formed between C-lobe of bovine lactoferrin and 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine at 2.25 A resolution
To be Published
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3CI8
 | | Crystal structure of the complex of C-lobe of lactoferrin with vitamin B3 (niacin) at 2.4 A resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ... | | 著者 | Kushwaha, G.S, Vikram, G, Singh, N, Sharma, S, Kaur, P, Singh, T.P. | | 登録日 | 2008-03-11 | | 公開日 | 2008-03-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the complex of C-lobe of lactoferrin with vitamin B3 (niacin) at 2.4 A resolution
To be Published
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3CR9
 | | Crystal structure of the complex of Lactoferrin with 6-(Hydroxymethyl)oxane-2,3,4,5-tetrol at 3.49 A resolution | | 分子名称: | FE (III) ION, Lactotransferrin, alpha-D-glucopyranose | | 著者 | Mir, R, Kaur, A, Singh, A.K, Singh, N, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2008-04-05 | | 公開日 | 2008-04-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | | 主引用文献 | Crystal structure of the complex of Lactoferrin with 6-(Hydroxymethyl)oxane-2,3,4,5-tetrol at 3.49 A resolution
To be Published
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2CHP
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2CF7
 | | Asp74Ala mutant crystal structure for Dps-like peroxide resistance protein Dpr from Streptococcus suis. | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kauko, A, Pulliainen, A.T, Haataja, S, Finne, J, Papageorgiou, A.C. | | 登録日 | 2006-02-16 | | 公開日 | 2006-09-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Iron incorporation in Streptococcus suis Dps-like peroxide resistance protein Dpr requires mobility in the ferroxidase center and leads to the formation of a ferrihydrite-like core.
J. Mol. Biol., 364, 2006
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2BW1
 | | Iron-bound crystal structure of Dps-like peroxide resistance protein (Dpr) from Streptococcus suis. | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, DPS-LIKE PEROXIDE RESISTANCE PROTEIN, ... | | 著者 | Kauko, A, Pulliainen, A, Haataja, S, Finne, J, Papageorgiou, A.C. | | 登録日 | 2005-07-07 | | 公開日 | 2006-09-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Iron incorporation in Streptococcus suis Dps-like peroxide resistance protein Dpr requires mobility in the ferroxidase center and leads to the formation of a ferrihydrite-like core.
J. Mol. Biol., 364, 2006
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7QBP
 | | Crystal structure of R2-like ligand-binding oxidase from Saccharopolyspora Erythraea | | 分子名称: | FE (III) ION, MANGANESE (III) ION, PALMITIC ACID, ... | | 著者 | Srinivas, V, Diamanti, R, Lebrette, H, Hogbom, M. | | 登録日 | 2021-11-19 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Comparative structural analysis provides new insights into the function of R2-like ligand-binding oxidase.
Febs Lett., 596, 2022
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7QBK
 | | Crystal structure of a second homolog of R2-like ligand-binding oxidase in Sulfolobus acidocaldarius (SaR2loxII) | | 分子名称: | FE (III) ION, MANGANESE (III) ION, R2-like ligand-binding oxidase (homolog II) from Sulfolobus acidocaldarius | | 著者 | Lebrette, H, Diamanti, R, Srinivas, V, Hogbom, M. | | 登録日 | 2021-11-19 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Comparative structural analysis provides new insights into the function of R2-like ligand-binding oxidase.
Febs Lett., 596, 2022
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7VVS
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4A25
 | | X-ray structure Dps from Kineococcus radiotolerans in complex with Mn (II) ions. | | 分子名称: | CHLORIDE ION, FERRITIN DPS FAMILY PROTEIN, MANGANESE (II) ION | | 著者 | Ilari, A, Fiorillo, A, Ardini, M, Stefanini, S, Chiancone, E. | | 登録日 | 2011-09-22 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Kineococcus Radiotolerans Dps Forms a Heteronuclear Mn-Fe Ferroxidase Center that May Explain the Mn-Dependent Protection Against Oxidative Stress.
Biochim.Biophys.Acta, 1830, 2013
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6B0D
 | | An E. coli DPS protein from ferritin superfamily | | 分子名称: | DNA protection during starvation protein, FORMIC ACID, SODIUM ION | | 著者 | Rui, W, Ruslan, S, Ronan, K, Adam, J.S. | | 登録日 | 2017-09-14 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | SIMBAD: a sequence-independent molecular-replacement pipeline.
Acta Crystallogr D Struct Biol, 74, 2018
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5K52
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5HJH
 | | Dps4 from Nostoc punctiforme in complex with Fe ions | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FE (III) ION, Ferritin, ... | | 著者 | Howe, C, Moparthi, V.K, Persson, K, Stensjo, K. | | 登録日 | 2016-01-13 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Dps4 from Nostoc punctiforme in complex with Fe ions
To Be Published
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8HX1
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8HX0
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6LS0
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6LS3
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2WFO
 | | Crystal structure of Machupo virus envelope glycoprotein GP1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCOPROTEIN 1 | | 著者 | Bowden, T.A, Crispin, M, Graham, S.C, Harvey, D.J, Grimes, J.M, Jones, E.Y, Stuart, D.I. | | 登録日 | 2009-04-09 | | 公開日 | 2009-06-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Unusual Molecular Architecture of the Machupo Virus Attachment Glycoprotein.
J.Virol., 83, 2009
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3HJP
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8ZM1
 | | Structure of human pyruvate dehydrogenase kinase 2 complexed with compound 6 | | 分子名称: | (5~{R})-5-propan-2-ylindeno[1,2-b]pyridin-5-ol, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | | 著者 | Akai, S, Orita, T, Nomura, A, Adachi, T. | | 登録日 | 2024-05-22 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Design and synthesis of novel fluorene derivatives as inhibitors of pyruvate dehydrogenase kinase.
Bioorg.Med.Chem.Lett., 109, 2024
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8ZM2
 | | Structure of human pyruvate dehydrogenase kinase 2 complexed with compound 16 | | 分子名称: | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial, methyl (9~{R})-9-oxidanyl-9-(trifluoromethyl)fluorene-4-carboxylate | | 著者 | Akai, S, Orita, T, Nomura, A, Adachi, T. | | 登録日 | 2024-05-22 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Design and synthesis of novel fluorene derivatives as inhibitors of pyruvate dehydrogenase kinase.
Bioorg.Med.Chem.Lett., 109, 2024
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6KM9
 | | Crystal structure of SucA from Vibrio vulnificus | | 分子名称: | CALCIUM ION, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ... | | 著者 | Seo, P.W, Kim, J.S. | | 登録日 | 2019-07-31 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.724 Å) | | 主引用文献 | Understanding the molecular properties of the E1 subunit (SucA) of alpha-ketoglutarate dehydrogenase complex from Vibrio vulnificus for the enantioselective ligation of acetaldehydes into (R)-acetoin.
Catalysis Science And Technology, 2020
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6LIN
 | | Crystal structure of human PDK2 complexed with GM10030 | | 分子名称: | 4-[[[4-[3,5-bis(fluoranyl)-4-(4-oxidanyl-4-oxidanylidene-butoxy)phenyl]-5-[5-chloranyl-2,4-bis(oxidanyl)phenyl]-1,2-oxazol-3-yl]carbonylamino]methyl]benzoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Kang, J, Kim, J. | | 登録日 | 2019-12-12 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Structural basis for the inhibition of PDK2 by novel ATP- and lipoyl-binding site targeting compounds.
Biochem.Biophys.Res.Commun., 527, 2020
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4V25
 | | VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context- dependent cytostasis in cancer cells | | 分子名称: | MAGNESIUM ION, N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE, N-[4-(2-chloro-5-methylpyrimidin-4-yl)phenyl]-N-(4-{[(difluoroacetyl)amino]methyl}benzyl)-2,4-dihydroxybenzamide, ... | | 著者 | Moore, J.D, Staniszewska, A, Shaw, T, D'Alessandro, J, Davis, B, Surgenor, A, Baker, L, Matassova, N, Murray, J, Macias, A, Brough, P, Wood, M, Mahon, P.C. | | 登録日 | 2014-10-06 | | 公開日 | 2014-12-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells.
Oncotarget, 5, 2014
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4V26
 | | VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context- dependent cytostasis in cancer cells | | 分子名称: | MAGNESIUM ION, N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE, N-[4-(2-CHLORO-5-METHYLPYRIMIDIN-4-YL)PHENYL]-2,4-DIHYDROXY-N-(4-{[(TRIFLUOROACETYL)AMINO]METHYL}BENZYL)BENZAMIDE, ... | | 著者 | Moore, J.D, Staniszewska, A, Shaw, T, D'Alessandro, J, Davis, B, Surgenor, A, Baker, L, Matassova, N, Murray, J, Macias, A, Brough, P, Wood, M, Mahon, P.C. | | 登録日 | 2014-10-06 | | 公開日 | 2014-12-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells.
Oncotarget, 5, 2014
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