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5UHY
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A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection
分子名称: ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein
著者Hasan, S.S, Miller, A, Sapparapu, G, Fernandez, E, Klose, T, Long, F, Fokine, A, Porta, J.C, Jiang, W, Diamond, M.S, Crowe Jr, J.E, Kuhn, R.J, Rossmann, M.G.
登録日2017-01-12
公開日2017-03-29
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
5L4O
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Structure of an E.coli initiator tRNAfMet A1-U72 variant
分子名称: SODIUM ION, tRNA (76-MER)
著者Monestier, A, Schmitt, E, Mechulam, Y.
登録日2016-05-26
公開日2017-03-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献The structure of an E. coli tRNAf(Met) A1-U72 variant shows an unusual conformation of the A1-U72 base pair.
RNA, 23, 2017
2VMK
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Crystal Structure of E. coli RNase E Apoprotein - Catalytic Domain
分子名称: RIBONUCLEASE E, SULFATE ION, ZINC ION
著者Koslover, D.J, Callaghan, A.J, Marcaida, M.J, Martick, M, Scott, W.G, Luisi, B.F.
登録日2008-01-28
公開日2008-07-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The Crystal Structure of the Escherichia Coli Rnase E Apoprotein and a Mechanism for RNA Degradation.
Structure, 16, 2008
3KXP
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Crystal Structure of E-2-(Acetamidomethylene)succinate Hydrolase
分子名称: Alpha-(N-acetylaminomethylene)succinic acid hydrolase, CHLORIDE ION
著者McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E.
登録日2009-12-03
公開日2010-02-09
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structure determination and characterization of the vitamin B(6) degradative enzyme (E)-2-(acetamidomethylene)succinate hydrolase.
Biochemistry, 49, 2010
5U7H
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Ni-bound dihydroneopterin triphosphate pyrophosphohydrolase from E. coli
分子名称: Dihydroneopterin triphosphate diphosphatase, NICKEL (II) ION, SULFATE ION
著者Nguyen, E, Hill, S.E, Lieberman, R.L.
登録日2016-12-12
公開日2017-06-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Metal ion coordination in the E. coli Nudix hydrolase dihydroneopterin triphosphate pyrophosphatase: New clues into catalytic mechanism.
PLoS ONE, 12, 2017
5U7F
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Co-bound dihydroneopterin triphosphate pyrophosphohydrolase from E. coli
分子名称: COBALT (II) ION, Dihydroneopterin triphosphate diphosphatase, SULFATE ION
著者Nguyen, E, Hill, S.E, Lieberman, R.L.
登録日2016-12-12
公開日2017-06-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.789 Å)
主引用文献Metal ion coordination in the E. coli Nudix hydrolase dihydroneopterin triphosphate pyrophosphatase: New clues into catalytic mechanism.
PLoS ONE, 12, 2017
1SE7
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Solution structure of the E. coli bacteriophage P1 encoded HOT protein: a homologue of the theta subunit of E. coli DNA polymerase III
分子名称: HOMOLOGUE OF THE THETA SUBUNIT OF DNA POLYMERASE III
著者DeRose, E.F, Kirby, T.W, Mueller, G.A, Chikova, A.K, Schaaper, R.M, London, R.E.
登録日2004-02-16
公開日2004-12-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Phage Like It HOT: Solution Structure of the Bacteriophage P1-Encoded HOT Protein, a Homolog of the theta Subunit of E. coli DNA Polymerase III
Structure, 12, 2004
5U7E
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Apo dihydroneopterin triphosphate pyrophosphohydrolase from E. coli
分子名称: Dihydroneopterin triphosphate diphosphatase, GLYCEROL, SULFATE ION
著者Nguyen, E, Hill, S.E, Lieberman, R.L.
登録日2016-12-12
公開日2017-06-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.942 Å)
主引用文献Metal ion coordination in the E. coli Nudix hydrolase dihydroneopterin triphosphate pyrophosphatase: New clues into catalytic mechanism.
PLoS ONE, 12, 2017
2O72
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Crystal Structure Analysis of human E-cadherin (1-213)
分子名称: CALCIUM ION, Epithelial-cadherin
著者Parisini, E, Wang, J.-H.
登録日2006-12-09
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of Human E-cadherin Domains 1 and 2, and Comparison with other Cadherins in the Context of Adhesion Mechanism
J.Mol.Biol., 373, 2007
1LTB
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2.6 ANGSTROMS CRYSTAL STRUCTURE OF PARTIALLY-ACTIVATED E. COLI HEAT-LABILE ENTEROTOXIN (LT)
分子名称: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B
著者Merritt, E.A, Sixma, T.K, Hol, W.G.J.
登録日1993-09-15
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of partially-activated E. coli heat-labile enterotoxin (LT) at 2.6 A resolution.
FEBS Lett., 337, 1994
5W3Q
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L28F E.coli DHFR in complex with NADPH
分子名称: CALCIUM ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Oyen, D, Wright, P.E, Wilson, I.A.
登録日2017-06-08
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion.
J. Am. Chem. Soc., 139, 2017
4ZT1
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Crystal structure of human E-Cadherin (residues 3-213) in x-dimer conformation
分子名称: CALCIUM ION, Cadherin-1
著者Nardone, V, Lucarelli, A.P, Dalle Vedove, A, Parisini, E.
登録日2015-05-14
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal Structure of Human E-Cadherin-EC1EC2 in Complex with a Peptidomimetic Competitive Inhibitor of Cadherin Homophilic Interaction.
J.Med.Chem., 59, 2016
1ED3
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CRYSTAL STRUCTURE OF RAT MINOR HISTOCOMPATIBILITY ANTIGEN COMPLEX RT1-AA/MTF-E.
分子名称: BETA-2-MICROGLOBULIN, CLASS I MAJOR HISTOCOMPATIBILITY ANTIGEN RT1-AA, PEPTIDE MTF-E (13N3E)
著者Speir, J.A, Stevens, J, Joly, E, Butcher, G.W, Wilson, I.A.
登録日2000-01-26
公開日2001-02-28
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Two different, highly exposed, bulged structures for an unusually long peptide bound to rat MHC class I RT1-Aa.
Immunity, 14, 2001
4ZSW
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Pig Brain GABA-AT inactivated by (E)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic acid
分子名称: (1S)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-3-ene-1,3-dicarboxylic acid, 4-aminobutyrate aminotransferase, mitochondrial, ...
著者Wu, R, Lee, H, Le, H.V, Doud, E, Sanishvili, R, Compton, P, Kelleher, N.L, Silverman, R.B, Liu, D.
登録日2015-05-14
公開日2015-07-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid.
Acs Chem.Biol., 10, 2015
4ZTE
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Crystal structure of human E-Cadherin (residues 3-213) in complex with a peptidomimetic inhibitor
分子名称: CALCIUM ION, Cadherin-1, N-{[(2S,5S)-1-benzyl-5-(2-{[(2S,3S)-1-(tert-butylamino)-3-methyl-1-oxopentan-2-yl]amino}-2-oxoethyl)-3,6-dioxopiperazin-2-yl]methyl}-L-alpha-asparagine
著者Nardone, V, Lucarelli, A.P, Dalle Vedove, A, Parisini, E.
登録日2015-05-14
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal Structure of Human E-Cadherin-EC1EC2 in Complex with a Peptidomimetic Competitive Inhibitor of Cadherin Homophilic Interaction.
J.Med.Chem., 59, 2016
4HR7
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Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli
分子名称: 1,2-ETHANEDIOL, Biotin carboxyl carrier protein of acetyl-CoA carboxylase, Biotin carboxylase, ...
著者Broussard, T.C, Kobe, M.J, Pakhomova, S, Neau, D.B, Price, A.E, Champion, T.S, Waldrop, G.L.
登録日2012-10-26
公開日2013-03-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.495 Å)
主引用文献The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase.
Structure, 21, 2013
2GNN
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Crystal Structure of the Orf Virus NZ2 Variant of VEGF-E
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, ...
著者Prota, A.E, Pieren, M, Wagner, A, Kostrewa, D, Winkler, F.K, Ballmer-Hofer, K.
登録日2006-04-10
公開日2006-05-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the Orf virus NZ2 variant of vascular endothelial growth factor-E. Implications for receptor specificity.
J.Biol.Chem., 281, 2006
4C16
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E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic antagonist
分子名称: (1R,2R,3S)-3-methylcyclohexane-1,2-diol, (S)-CYCLOHEXYL LACTIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Preston, R.C, Jakob, R.P, Binder, F.P.C, Sager, C.P, Ernst, B, Maier, T.
登録日2013-08-09
公開日2014-08-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献E-Selectin Ligand Complexes Adopt an Extended High-Affinity Conformation.
J.Mol.Cell.Biol., 8, 2016
2XSC
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Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli
分子名称: SHIGA-LIKE TOXIN 1 SUBUNIT B, ZINC ION
著者Stein, P.E, Boodhoo, A, Tyrrell, G.J, Brunton, J.L, Oeffner, R.D, Bunkoczi, G, Read, R.J.
登録日2010-09-27
公開日2010-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.052 Å)
主引用文献Crystal Structure of the Cell-Binding B Oligomer of Verotoxin-1 from E. Coli.
Nature, 355, 1992
1EZZ
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CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE P268A MUTANT IN THE T-STATE
分子名称: ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ZINC ION
著者Jin, L, Stec, B, Kantrowitz, E.R.
登録日2000-05-12
公開日2000-11-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A cis-proline to alanine mutant of E. coli aspartate transcarbamoylase: kinetic studies and three-dimensional crystal structures.
Biochemistry, 39, 2000
1MBB
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OXIDOREDUCTASE
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, URIDINE DIPHOSPHO-N-ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE, URIDINE-DIPHOSPHATE-3(N-ACETYLGLUCOSAMINYL)BUTYRIC ACID
著者Benson, T.E, Lees, W.J, Walsh, C.T, Hogle, J.M.
登録日1995-11-07
公開日1996-10-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献(E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB).
Biochemistry, 35, 1996
4CSY
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E-selectin lectin, EGF-like and two SCR domains complexed with Sialyl Lewis X
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, E-SELECTIN, ...
著者Preston, R.C, Jakob, R.P, Binder, F.P.C, Sager, C.P, Ernst, B, Maier, T.
登録日2014-03-11
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献E-Selectin Ligand Complexes Adopt an Extended High-Affinity Conformation.
J.Mol.Cell.Biol., 8, 2016
4GEC
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Crystal Structure of E.coli MenH R124A Mutant
分子名称: 1,2-ETHANEDIOL, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, CHLORIDE ION, ...
著者Johnston, J.M, Baker, E.N, Guo, Z, Jiang, M.
登録日2012-08-01
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of E. coli Native MenH and Two Active Site Mutants.
Plos One, 8, 2013
4L8M
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Human p38 MAP kinase in complex with a Dibenzoxepinone
分子名称: Mitogen-activated protein kinase 14, N-[2-fluoro-5-({9-[2-(morpholin-4-yl)ethoxy]-11-oxo-6,11-dihydrodibenzo[b,e]oxepin-3-yl}amino)phenyl]benzamide, octyl beta-D-glucopyranoside
著者Richters, A, Mayer-Wrangowski, S.C, Gruetter, C, Rauh, D.
登録日2013-06-17
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Metabolically Stable Dibenzo[b,e]oxepin-11(6H)-ones as Highly Selective p38 MAP Kinase Inhibitors: Optimizing Anti-Cytokine Activity in Human Whole Blood.
J.Med.Chem., 56, 2013
4L1T
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Transthyretin in complex with (E)-3-(dimethylamino)-5-(4-hydroxy-3,5-dimethylstyryl)benzoic acid
分子名称: 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoic acid, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2013-06-03
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Fluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging-what we know and what we need to learn.
Biopolymers, 101, 2014

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