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6DQW
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Flavobacterium johnsoniae class Id ribonucleotide reductase alpha subuint
分子名称: Ribonucleoside-diphosphate reductase, alpha chain
著者Maggiolo, A.O, Boal, A.K.
登録日2018-06-11
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of Class Id Ribonucleotide Reductase Catalytic Subunits Reveal a Minimal Architecture for Deoxynucleotide Biosynthesis.
Biochemistry, 58, 2019
6MT9
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BU of 6mt9 by Molmil
X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP, ATP, and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Thomas, W.C, Brooks, F.P, Bacik, J.P, Ando, N.
登録日2018-10-19
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Convergent allostery in ribonucleotide reductase.
Nat Commun, 10, 2019
6MV9
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X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase, ...
著者Thomas, W.C, Brooks, F.P, Bacik, J.P, Ando, N.
登録日2018-10-24
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Convergent allostery in ribonucleotide reductase.
Nat Commun, 10, 2019
6MVE
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BU of 6mve by Molmil
Reduced X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP, ATP, and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Thomas, W.C, Brooks, F.P, Bacik, J.P, Ando, N.
登録日2018-10-25
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Convergent allostery in ribonucleotide reductase.
Nat Commun, 10, 2019
6MW3
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EM structure of Bacillus subtilis ribonucleotide reductase inhibited filament composed of NrdE alpha subunit and NrdF beta subunit with dATP
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Ribonucleoside-diphosphate reductase, Ribonucleoside-diphosphate reductase NrdF beta subunit
著者Thomas, W.C, Bacik, J.P, Kaelber, J.T, Ando, N.
登録日2018-10-29
公開日2019-06-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.65 Å)
主引用文献Convergent allostery in ribonucleotide reductase.
Nat Commun, 10, 2019
6MYX
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EM structure of Bacillus subtilis ribonucleotide reductase inhibited double-helical filament of NrdE alpha subunit with dATP
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Ribonucleoside-diphosphate reductase
著者Thomas, W.C, Bacik, J.P, Chen, J.Z, Ando, N.
登録日2018-11-02
公開日2019-06-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Convergent allostery in ribonucleotide reductase.
Nat Commun, 10, 2019
6L3R
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BU of 6l3r by Molmil
Crystal structure of Ribonucleotide reductase R1 subunit, RRM1 in complex with 4-bromo-N-((1S,2R)-2-(naphthalen-1-yl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)benzenesulfonamide
分子名称: 4-bromo-N-((1S,2R)-2-(naphthalen-1-yl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)benzenesulfonamide, ACETATE ION, MAGNESIUM ION, ...
著者Miyahara, S, Chong, K.T, Suzuki, T.
登録日2019-10-15
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献TAS1553, a novel small molecule ribonucleotide reductase (RNR) subunit interaction inhibitor, displays remarkable anti-tumor activity
To be published
6L7L
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BU of 6l7l by Molmil
Crystal structure of Ribonucleotide reductase R1 subunit, RRM1 in complex with 5-chloro-2-(N-((1S,2R)-2-(2,3-dihydro-1H-inden-4-yl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)sulfamoyl)benzamide
分子名称: 5-chloro-2-(N-((1S,2R)-2-(2,3-dihydro-1H-inden-4-yl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)sulfamoyl)benzamide, ACETATE ION, MAGNESIUM ION, ...
著者Miyahara, S, Chong, K.T, Suzuki, T.
登録日2019-11-01
公開日2020-11-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.171 Å)
主引用文献TAS1553, a novel small molecule ribonucleotide reductase (RNR) subunit interaction inhibitor, displays remarkable anti-tumor activity
To be published
6LKM
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BU of 6lkm by Molmil
Crystal structure of Ribonucleotide reductase R1 subunit, RRM1 in complex with 5-chloro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)-4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-sulfonamide
分子名称: 5-chloro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)-4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-sulfonamide, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large subunit, ...
著者Miyahara, S, Chong, K.T, Suzuki, T.
登録日2019-12-19
公開日2020-12-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献TAS1553, a novel small molecule ribonucleotide reductase (RNR) subunit interaction inhibitor, displays remarkable anti-tumor activity
To be published
6W4X
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BU of 6w4x by Molmil
Holocomplex of E. coli class Ia ribonucleotide reductase with GDP and TTP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MU-OXO-DIIRON, ...
著者Kang, G, Taguchi, A, Stubbe, J, Drennan, C.
登録日2020-03-11
公開日2020-04-08
最終更新日2020-05-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of a trapped radical transfer pathway within a ribonucleotide reductase holocomplex.
Science, 368, 2020
7AGJ
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BU of 7agj by Molmil
Ribonucleotide Reductase R1 protein from Aquifex aeolicus
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Rehling, D, Scaletti, E.R, Stenmark, P.
登録日2020-09-22
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus.
Biochemistry, 61, 2022
7B9Q
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BU of 7b9q by Molmil
The SERp optimized structure of Ribonucleotide reductase from Rhodobacter sphaeroides
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Vitamin B12-dependent ribonucleotide reductase
著者Loderer, C, Feiler, C, Wilk, P, Kabinger, F.
登録日2020-12-14
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase.
Biochemistry, 61, 2022
7B9P
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BU of 7b9p by Molmil
Structure of Ribonucleotide reductase from Rhodobacter sphaeroides
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Vitamin B12-dependent ribonucleotide reductase
著者Wilk, P, Feiler, C, Loderer, C, Kabinger, F.
登録日2020-12-14
公開日2022-01-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.646 Å)
主引用文献HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase.
Biochemistry, 61, 2022
7MDI
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BU of 7mdi by Molmil
Structure of the Neisseria gonorrhoeae ribonucleotide reductase in the inactive state
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Levitz, T.S, Drennan, C.L, Brignole, E.J.
登録日2021-04-05
公開日2022-01-05
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Effects of chameleon dispense-to-plunge speed on particle concentration, complex formation, and final resolution: A case study using the Neisseria gonorrhoeae ribonucleotide reductase inactive complex.
J.Struct.Biol., 214, 2021
7RW6
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BU of 7rw6 by Molmil
BORF2-APOBEC3Bctd Complex
分子名称: DNA dC->dU-editing enzyme APOBEC-3B, Maltose/maltodextrin-binding periplasmic protein,Ribonucleoside-diphosphate reductase large subunit, ZINC ION
著者Shaban, N.M, Yan, R, Shi, K, McLellan, J.S, Yu, Z, Harris, R.S.
登録日2021-08-19
公開日2022-04-27
最終更新日2022-05-04
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition.
Sci Adv, 8, 2022
7URG
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BU of 7urg by Molmil
cryo-EM structure of ribonucleotide reductase from Synechococcus phage S-CBP4 bound with TTP
分子名称: Ribonucleotide reductase, THYMIDINE-5'-TRIPHOSPHATE
著者Xu, D, Burnim, A.A, Ando, N.
登録日2022-04-21
公開日2022-09-07
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Comprehensive phylogenetic analysis of the ribonucleotide reductase family reveals an ancestral clade.
Elife, 11, 2022
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件を2024-06-12に公開中

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