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2VOT
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BU of 2vot by Molmil
Structural and biochemical evidence for a boat-like transition state in beta-mannosidases
分子名称: (5R,6R,7S,8R)-6,7,8-trihydroxy-5-(hydroxymethyl)-2-[(phenylamino)methyl]-5,6,7,8-tetrahydro-1H-imidazo[1,2-a]pyridin-4-ium, 1,2-ETHANEDIOL, BETA-MANNOSIDASE, ...
著者Tailford, L.N, Offen, W.A, Smith, N, Dumon, C, Moreland, C, Gratien, J, Heck, M.-P, Stick, R.V, Bleriot, Y, Vasella, A, Gilbert, H.J, Davies, G.J.
登録日2008-02-20
公開日2008-04-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
6QUB
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BU of 6qub by Molmil
Truncated beta-galactosidase III from Bifidobacterium bifidum in complex with galactose
分子名称: Beta-galactosidase, CALCIUM ION, beta-D-galactopyranose
著者Thirup, S.S, Nielsen, J.A, Andersen, J.L, Alsarraf, H, Blaise, M.
登録日2019-02-27
公開日2020-03-18
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Truncated beta-galactosidase III from Bifidobacterium bifidum
To Be Published
6QUC
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BU of 6quc by Molmil
Truncated beta-galactosidase III from Bifidobacterium bifidum
分子名称: Beta-galactosidase, CALCIUM ION, IMIDAZOLE
著者Thirup, S.S, Nielsen, J.A, Andersen, J.L, Alsarraf, H, Blaise, M.
登録日2019-02-27
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Truncated beta-galactosidase III from Bifidobacterium bifidum
To Be Published
6QUD
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BU of 6qud by Molmil
2-deoxy-galactose reaction intermediate of a Truncated beta-galactosidase III from Bifidobacterium bifidum
分子名称: 2-deoxy-alpha-D-galactopyranose, Beta-galactosidase, CALCIUM ION
著者Thirup, S.S, Nielsen, J.A, Andersen, J.L, Alsarraf, H, Blaise, M.
登録日2019-02-27
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Truncated beta-galactosidase III from Bifidobacterium bifidum
To Be Published
6S6Z
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BU of 6s6z by Molmil
Structure of beta-Galactosidase from Thermotoga maritima
分子名称: Beta-galactosidase, MAGNESIUM ION
著者Miguez-Amil, S, Jimenez-Ortega, E, Ramirez Escudero, M, Sanz-Aparicio, J, Fernandez-Leiro, R.
登録日2019-07-04
公開日2020-03-18
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献The cryo-EM Structure ofThermotoga maritimabeta-Galactosidase: Quaternary Structure Guides Protein Engineering.
Acs Chem.Biol., 15, 2020
6B6L
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BU of 6b6l by Molmil
The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Glycosyl hydrolase family 2, ...
著者Tan, K, Joachimiak, G, Nocek, B, Enddres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2017-10-02
公開日2017-10-11
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838
To Be Published
5T98
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BU of 5t98 by Molmil
Crystal structure of BuGH2Awt
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycoside Hydrolase
著者Pluvinage, B, Boraston, A.B.
登録日2016-09-09
公開日2017-09-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont.
Nat Commun, 9, 2018
5T9A
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BU of 5t9a by Molmil
Crystal structure of BuGH2Cwt
分子名称: 1,2-ETHANEDIOL, Glycoside Hydrolase, SULFATE ION
著者Pluvinage, B, Boraston, A.B, Abbott, W.D.
登録日2016-09-09
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont.
Nat Commun, 9, 2018
6BJW
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BU of 6bjw by Molmil
Eubacterium eligens Beta-glucuronidase
分子名称: Glycoside Hydrolase Family 2 candidate b-glucuronidase
著者Pellock, S.J, Walton, W.G, Redinbo, M.R.
登録日2017-11-07
公開日2018-07-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6SD0
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BU of 6sd0 by Molmil
Structure of beta-galactosidase from Thermotoga maritima.
分子名称: Beta-galactosidase, MAGNESIUM ION
著者Jimenez-Ortega, E, Ramirez-Escudero, M, Sanz-Aparicio, J.
登録日2019-07-26
公開日2020-01-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献The cryo-EM Structure ofThermotoga maritimabeta-Galactosidase: Quaternary Structure Guides Protein Engineering.
Acs Chem.Biol., 15, 2020
5T9G
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BU of 5t9g by Molmil
Crystal structure of BuGH2Cwt in complex with Galactoisofagomine
分子名称: 1,2-ETHANEDIOL, D-galacto-isofagomine, Glycoside Hydrolase
著者Pluvinage, B, Boraston, A.B.
登録日2016-09-09
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont.
Nat Commun, 9, 2018
5UJ6
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BU of 5uj6 by Molmil
Crystal Structure of Bacteroides Uniformis beta-glucuronidase
分子名称: CALCIUM ION, GLYCEROL, Glycosyl hydrolases family 2, ...
著者Walton, W.G, Redinbo, M.R.
登録日2017-01-17
公開日2017-06-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An Atlas of beta-Glucuronidases in the Human Intestinal Microbiome.
Structure, 25, 2017
6BO6
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BU of 6bo6 by Molmil
Eubacterium eligens beta-glucuronidase bound to UNC4917 glucuronic acid conjugate
分子名称: 4-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-2,7-bis(methylamino)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine, Glycoside Hydrolase Family 2 candidate b-glucuronidase
著者Pellock, S.J, Walton, W.G, Redinbo, M.R.
登録日2017-11-18
公開日2018-07-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6BJQ
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BU of 6bjq by Molmil
Eubacterium eligens beta-glucuronidase bound to glucuronic acid
分子名称: Glycoside Hydrolase Family 2 candidate b-glucuronidase, beta-D-glucopyranuronic acid
著者Pellock, S.J, Walton, W.G, Redinbo, M.R.
登録日2017-11-06
公開日2018-07-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
5T99
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BU of 5t99 by Molmil
Crystal structure of BuGH2Awt in complex with Galactoisofagomine
分子名称: 1,2-ETHANEDIOL, D-galacto-isofagomine, Glycoside Hydrolase
著者Pluvinage, B, Boraston, A.B.
登録日2016-09-09
公開日2017-09-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont.
Nat Commun, 9, 2018
6D1N
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BU of 6d1n by Molmil
Apo structure of Bacteroides uniformis Beta-glucuronidase 1
分子名称: Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, GLYCEROL
著者Walton, W.G, Pellock, S.J, Redinbo, M.R.
登録日2018-04-12
公開日2018-10-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
4CU7
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BU of 4cu7 by Molmil
Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA
分子名称: 1,2-ETHANEDIOL, BETA-GALACTOSIDASE, D-galacto-isofagomine, ...
著者Singh, A.K, Pluvinage, B, Higgins, M.A, Dalia, A.B, Flynn, M, Lloyd, A.R, Weiser, J.N, Stubbs, K.A, Boraston, A.B, King, S.J.
登録日2014-03-17
公開日2014-08-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus Pneumoniae Beta-Galactosidase, BgaA.
Plos Pathog., 10, 2014
4CKD
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BU of 4ckd by Molmil
Model of complex between the E.coli enzyme beta-galactosidase and four single chain Fv antibody domains scFv13R4.
分子名称: BETA-GALACTOSIDASE, SCFV13R4 ANTIBODY FV HEAVY CHAIN, SCFV13R4 ANTIBODY FV LIGHT CHAIN
著者Vinothkumar, K.R, McMullan, G, Henderson, R.
登録日2014-01-03
公開日2014-01-15
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Molecular Mechanism of Antibody-Mediated Activation of Beta-Galactosidase.
Structure, 22, 2014
4CVU
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BU of 4cvu by Molmil
Structure of Fungal beta-mannosidase from Glycoside Hydrolase Family 2 of Trichoderma harzianum
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-MANNOSIDASE, CADMIUM ION, ...
著者Muniz, J.R.C, Aparicio, R, Santos, J.C, Nascimento, A.S, Golubev, A.M, Polikarpov, I.
登録日2014-03-31
公開日2014-07-09
最終更新日2023-07-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into the structure and function of fungal beta-mannosidases from glycoside hydrolase family 2 based on multiple crystal structures of the Trichoderma harzianum enzyme.
FEBS J., 281, 2014
4CUC
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BU of 4cuc by Molmil
Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, BETA-GALACTOSIDASE, SULFATE ION, ...
著者Singh, A.K, Pluvinage, B, Higgins, M.A, Dalia, A.B, Flynn, M, Lloyd, A.R, Weiser, J.N, Stubbs, K.A, Boraston, A.B, King, S.J.
登録日2014-03-17
公開日2014-08-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus Pneumoniae Beta-Galactosidase, BgaA.
Plos Pathog., 10, 2014
4CU6
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BU of 4cu6 by Molmil
Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA
分子名称: 1,2-ETHANEDIOL, BETA-GALACTOSIDASE, SULFATE ION
著者Singh, A.K, Pluvinage, B, Higgins, M.A, Dalia, A.B, Flynn, M, Lloyd, A.R, Weiser, J.N, Stubbs, K.A, Boraston, A.B, King, S.J.
登録日2014-03-17
公開日2014-08-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus Pneumoniae Beta-Galactosidase, Bgaa.
Plos Pathog., 10, 2014
8GEN
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BU of 8gen by Molmil
E. eligens beta-glucuronidase bound to UNC10201652-glucuronide
分子名称: 8-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5-(morpholin-4-yl)-1,2,3,4-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3 -c]isoquinoline, Beta-glucuronidase
著者Simpson, J.B, Redinbo, M.R.
登録日2023-03-07
公開日2024-02-14
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics.
Cell Host Microbe, 32, 2024
8GEQ
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BU of 8geq by Molmil
E. eligens beta-glucuronidase bound to ceritinib-glucuronide
分子名称: 4-amino-5-chloro-2-{4-(1-beta-D-glucopyranuronosylpiperidin-4-yl)-5-methyl-2-[(propan-2-yl)oxy]anilino}pyrimidine, Beta-glucuronidase
著者Simpson, J.B, Kowalewski, M.K, Redinbo, M.R.
登録日2023-03-07
公開日2024-02-14
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics.
Cell Host Microbe, 32, 2024
8GES
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BU of 8ges by Molmil
R. hominis 2 beta-glucuronidase bound to UNC10201652-glucuronide
分子名称: 8-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5-(morpholin-4-yl)-1,2,3,4-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3 -c]isoquinoline, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Simpson, J.B, Redinbo, M.R.
登録日2023-03-07
公開日2024-02-14
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics.
Cell Host Microbe, 32, 2024
8GET
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BU of 8get by Molmil
R. hominis 2 beta-glucuronidase bound to norquetiapine-glucuronide
分子名称: 11-(4-beta-D-glucopyranuronosylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Simpson, J.B, Redinbo, M.R.
登録日2023-03-07
公開日2024-03-20
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics.
Cell Host Microbe, 32, 2024

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件を2024-09-11に公開中

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