7MJF
 
 | | Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site | | 分子名称: | (4R)-4-oxidanyl-2-oxidanylidene-heptanedioic acid, (4S)-4-hydroxy-2-oxoheptanedioic acid, 4-hydroxy-tetrahydrodipicolinate synthase | | 著者 | Gilkes, J, Frampton, R.A, Board, A.J, Sheen, C.R, Smith, G.R, Dobson, R.C.J. | | 登録日 | 2021-04-20 | | 公開日 | 2021-07-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
To Be Published
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2ATS
 | | Dihydrodipicolinate synthase co-crystallised with (S)-lysine | | 分子名称: | CHLORIDE ION, D-LYSINE, POTASSIUM ION, ... | | 著者 | Devenish, S.R.A, Dobson, R.C.J, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2005-08-26 | | 公開日 | 2006-09-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The co-crystallisation of (S)-lysine-bound dihydrodipicolinate synthase from E. coli indicates that domain movements are not responsible for (S)-lysine inhibition
To be published
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7MDS
 | | Crystal structure of AtDHDPS1 in complex with MBDTA-2 | | 分子名称: | 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, CHLORIDE ION, ... | | 著者 | Hall, C.J, Soares da Costa, T.P, Panjikar, S. | | 登録日 | 2021-04-06 | | 公開日 | 2021-08-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | | 主引用文献 | Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants.
Elife, 10, 2021
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5HWJ
 | | Crystal structure of keto-deoxy-D-galactarate dehydratase | | 分子名称: | FORMIC ACID, GLYCEROL, Probable 5-dehydro-4-deoxyglucarate dehydratase | | 著者 | Taberman, H, Parkkinen, T, Hakulinen, N, Rouvinen, J. | | 登録日 | 2016-01-29 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.648 Å) | | 主引用文献 | Structure and function of a decarboxylating Agrobacterium tumefaciens keto-deoxy-d-galactarate dehydratase.
Biochemistry, 53, 2014
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5F1V
 | | biomimetic design results in a potent allosteric inhibitor of dihydrodipicolinate synthase from Campylobacter jejuni | | 分子名称: | (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ... | | 著者 | Conly, C.J.T, Palmer, D.R.J, Sanders, D.A.R. | | 登録日 | 2015-11-30 | | 公開日 | 2016-02-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni.
J.Am.Chem.Soc., 138, 2016
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5HWN
 | | Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with pyruvate | | 分子名称: | FORMIC ACID, GLYCEROL, PYRUVIC ACID, ... | | 著者 | Taberman, H, Parkkinen, T, Hakulinen, N, Rouvinen, J. | | 登録日 | 2016-01-29 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | | 主引用文献 | Structure and function of a decarboxylating Agrobacterium tumefaciens keto-deoxy-d-galactarate dehydratase.
Biochemistry, 53, 2014
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5HWM
 | | Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with 2-oxoadipic acid | | 分子名称: | 2-OXOADIPIC ACID, FORMIC ACID, Probable 5-dehydro-4-deoxyglucarate dehydratase | | 著者 | Taberman, H, Parkkinen, T, Hakulinen, N, Rouvinen, J. | | 登録日 | 2016-01-29 | | 公開日 | 2016-03-23 | | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | | 主引用文献 | Structure and function of a decarboxylating Agrobacterium tumefaciens keto-deoxy-d-galactarate dehydratase.
Biochemistry, 53, 2014
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6VVI
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6VVH
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1YXC
 | | Structure of E. coli dihydrodipicolinate synthase to 1.9 A | | 分子名称: | CHLORIDE ION, POTASSIUM ION, dihydrodipicolinate synthase | | 著者 | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2005-02-20 | | 公開日 | 2005-08-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Acta Crystallogr.,Sect.D, 61, 2005
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1YXD
 | | Structure of E. coli dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine to 2.0 A | | 分子名称: | CHLORIDE ION, LYSINE, POTASSIUM ION, ... | | 著者 | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2005-02-20 | | 公開日 | 2005-08-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Acta Crystallogr.,Sect.D, 61, 2005
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8U91
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8U92
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8U90
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8U93
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8U8W
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8UR1
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4AHQ
 | | Crystal Structure of N-acetylneuraminic acid lyase mutant K165C from Staphylococcus aureus | | 分子名称: | N-ACETYLNEURAMINATE LYASE | | 著者 | Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A. | | 登録日 | 2012-02-06 | | 公開日 | 2013-01-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
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4AHP
 | | Crystal Structure of Wild Type N-acetylneuraminic acid lyase from Staphylococcus aureus | | 分子名称: | CHLORIDE ION, N-ACETYLNEURAMINATE LYASE | | 著者 | Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A. | | 登録日 | 2012-02-06 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
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6H2R
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6H7R
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4AHO
 | | Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165 | | 分子名称: | CHLORIDE ION, N-ACETYLNEURAMINATE LYASE | | 著者 | Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A. | | 登録日 | 2012-02-06 | | 公開日 | 2013-01-23 | | 最終更新日 | 2013-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
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6H7S
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6H4E
 | | Proteus mirabilis N-acetylneuraminate lyase | | 分子名称: | Putative N-acetylneuraminate lyase, SULFATE ION | | 著者 | North, R.A, Garcia-Bonete, M.J, Goyal, P, Katona, G, Dobson, R.C.J, Friemann, R. | | 登録日 | 2018-07-21 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.561 Å) | | 主引用文献 | The structure of Proteus mirabilis N-acetylneuraminate lyase reveals an intermolecular disulphide bond
To Be Published
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6GV2
 | | Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase Y103F,Y130F,A198F variant in complex with L-2-keto, 3-deoxy-galactonate | | 分子名称: | 1,2-ETHANEDIOL, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase, 3-DEOXY-D-ARABINO-HEXONIC ACID, ... | | 著者 | Crennell, S.J, Danson, M.J, Royer, S. | | 登録日 | 2018-06-20 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase Y132V,T157C variant
To Be Published
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