5F1V

biomimetic design results in a potent allosteric inhibitor of dihydrodipicolinate synthase from Campylobacter jejuni

Summary for 5F1V

Entry DOI	10.2210/pdb5f1v/pdb
Related	5F1U
Descriptor	4-hydroxy-tetrahydrodipicolinate synthase, (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, TRIETHYLENE GLYCOL, ... (6 entities in total)
Functional Keywords	schiff-base, aldolase, tim barrel, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological source	Campylobacter jejuni
Total number of polymer chains	4
Total formula weight	132969.05
Authors	Conly, C.J.T.,Palmer, D.R.J.,Sanders, D.A.R. (deposition date: 2015-11-30, release date: 2016-02-17, Last modification date: 2023-11-29)
Primary citation	Skovpen, Y.V.,Conly, C.J.,Sanders, D.A.,Palmer, D.R. Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni. J.Am.Chem.Soc., 138:2014-2020, 2016 Cited by PubMed: 26836694 DOI: 10.1021/jacs.5b12695 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation